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Volumn 670, Issue 1-2, 2010, Pages 84-91
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Simultaneous determination of plasma epinephrine and norepinephrine using an integrated strategy of a fully automated protein precipitation technique, reductive ethylation labeling and UPLC-MS/MS
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Author keywords
Automation; Plasma epinephrine and norepinephrine; Protein precipitation; Quantification; Reductive ethylation; Ultra performance liquid chromatography tandem mass spectrometry
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Indexed keywords
96-WELL PLATE;
ACCURACY AND PRECISION;
AMINO GROUP;
CALIBRATION SAMPLES;
CLEAN UP;
COEFFICIENT OF VARIATION;
DETECTION SENSITIVITY;
HAMILTONS;
HIGH-THROUGHPUT;
HUMAN PLASMAS;
INTEGRATED STRATEGY;
LABELING REAGENT;
LC-MS/MS;
LIMITS OF DETECTION;
LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY;
LIQUID HANDLING;
PLASMA SAMPLES;
PROCESSING TIME;
PROTEIN PRECIPITATION;
QUANTIFICATION;
ROBOTIC WORKSTATION;
RUNTIMES;
SAMPLE PREPARATION;
SIMULTANEOUS DETERMINATIONS;
STABILIZING ADDITIVES;
SUPERNATANTS;
ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;
UPLC-MS/MS;
AUTOMATION;
CHROMATOGRAPHY;
CUSTOMER SATISFACTION;
DRUG PRODUCTS;
HIGH PRESSURE LIQUID CHROMATOGRAPHY;
LABELING;
LIQUIDS;
MASS SPECTROMETRY;
PLASMAS;
PROTEINS;
QUALITY ASSURANCE;
TOTAL QUALITY MANAGEMENT;
QUALITY CONTROL;
ADRENALIN;
AMINE;
NORADRENALIN;
ACCURACY;
ARTICLE;
AUTOMATION;
BLOOD ANALYSIS;
BLOOD SAMPLING;
CHEMICAL STRUCTURE;
CONCENTRATION (PARAMETERS);
CONTROLLED STUDY;
DERIVATIZATION;
HIGH THROUGHPUT SCREENING;
HUMAN;
MOUSE;
NONHUMAN;
PRECIPITATION;
PRIORITY JOURNAL;
QUADRUPOLE MASS SPECTROMETRY;
QUALITY CONTROL;
RAT;
ROBOTICS;
SENSITIVITY AND SPECIFICITY;
SUPERNATANT;
TANDEM MASS SPECTROMETRY;
ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;
ANIMALS;
CHEMICAL PRECIPITATION;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
EPINEPHRINE;
MICE;
MOLECULAR STRUCTURE;
NOREPINEPHRINE;
RATS;
TANDEM MASS SPECTROMETRY;
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EID: 77953810758
PISSN: 00032670
EISSN: 18734324
Source Type: Journal
DOI: 10.1016/j.aca.2010.04.051 Document Type: Article |
Times cited : (85)
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References (36)
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