Analysis of the functional consequences of lethal mutations in mitochondrial translational elongation factors

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1802, Issue 7-8, 2010, Pages 692-698

  Akama, Kenta ^a   Christian, Brooke E ^b   Jones, Christie N ^b   Ueda, Takuya ^a   Takeuchi, Nono ^a   Spremulli, Linda L ^b  

^a UNIVERSITY OF TOKYO   (Japan)

^b University of North Carolina at Chapel Hill   (United States)

Author keywords

Disease; EF Ts; EF Tu; Elongation; Mitochondria; Translation

Indexed keywords

AMINO ACID TRANSFER RNA LIGASE; ARGININE; CARBON 14; ELONGATION FACTOR; GLUTAMINE; NUCLEOTIDE; PHENYLALANINE; POLYPEPTIDE; TRANSFER RNA;

ARTICLE; BRAIN DISEASE; ESCHERICHIA COLI; GENE MUTATION; LETHAL GENE; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN SYNTHESIS; RIBOSOME; RNA TRANSLATION; WILD TYPE;

AMINO ACID SUBSTITUTION; ANIMALS; CATTLE; ESCHERICHIA COLI PROTEINS; GENES, LETHAL; MITOCHONDRIA; MODELS, MOLECULAR; MUTANT PROTEINS; MUTATION; PEPTIDE ELONGATION FACTOR TU; PEPTIDE ELONGATION FACTORS; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; PROTEIN MULTIMERIZATION; RNA, TRANSFER, AMINO ACID-SPECIFIC; STRUCTURE-ACTIVITY RELATIONSHIP;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; MAMMALIA;

EID: 77953810140     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2010.04.003     Document Type: Article

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