Interaction of a new anticancer prodrug, gemcitabine-squalene, with a model membrane. Coupled DSC and XRD study.

Biochimica et Biophysica Acta - Biomembranes

Volumn 1798, Issue 8, 2010, Pages 1522-1532

  Pili, Barbara ^a   Bourgaux, Claudie ^a   Amenitsch, Heinz ^b,c   Keller, Gérard ^a   Lepêtre Mouelhi, Sinda ^a   Desmaële, Didier ^a   Couvreur, Patrick ^a   Ollivon, Michel ^a  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b SINCROTRONE TRIESTE   (Italy)

^c Institute of Biophysics and Nanosystems Research   (Austria)

Author keywords

Anticancer prodrug; Differential scanning calorimetry; Gemcitabine squalene; Inverse bicontinue cubic phase; Prodrug membrane interaction; Small and wide angle X ray scattering

Indexed keywords

DIPALMITOYLPHOSPHATIDYLCHOLINE; GEMCITABINE; SQUALENE;

ARTICLE; CONCENTRATION RESPONSE; CONFORMATIONAL TRANSITION; DIFFERENTIAL SCANNING CALORIMETRY; HEATING; LIPID BILAYER; LIPID MEMBRANE; MEMBRANE MODEL; MEMBRANE STRUCTURE; PRIORITY JOURNAL; X RAY DIFFRACTION;

EID: 77953810106     PISSN: 00052736     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamem.2010.04.011     Document Type: Article

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