Supplementation with engineered Lactococcus lactis improves the folate status in deficient rats

Nutrition

Volumn 26, Issue 7-8, 2010, Pages 835-841

  LeBlanc, Jean Guy ^a   Sybesma, Wilbert ^b,c   Starrenburg, Marjo ^b,c   Sesma, Fernando ^a   de Vos, Willem M ^b   de Giori, Graciela Savoy ^a,d   Hugenholtz, Jeroen ^b,c  

^a CENTRO DE REFERENCIA PARA LACTOBACILOS CERELA CONICET   (Argentina)

^b TOP INSTITUTE FOOD AND NUTRITION   (Netherlands)

^c NIZO FOOD RESEARCH   (Netherlands)

^d UNIVERSIDAD NACIONAL DE TUCUMÁN   (Argentina)

Author keywords

Folate; Genetically modified microorganisms; Lactic acid bacteria

Indexed keywords

PROBIOTIC AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL STRAIN; BACTERIUM CULTURE; BIOAVAILABILITY; BIOENGINEERING; BLOOD SAMPLING; CONTROLLED STUDY; DEPLETION; FOLIC ACID DEFICIENCY; GENE EXPRESSION; LACTIC ACID BACTERIUM; LACTOCOCCUS LACTIS; MALE; MEGALOBLASTIC ANEMIA; NONHUMAN; PRIORITY JOURNAL; RAT; SUPPLEMENTATION;

ANEMIA, MEGALOBLASTIC; ANIMALS; BIOLOGICAL AVAILABILITY; DIETARY SUPPLEMENTS; FOLIC ACID; FOLIC ACID DEFICIENCY; GENES, BACTERIAL; GENETIC ENGINEERING; LACTOCOCCUS LACTIS; MALE; PROBIOTICS; RATS; RATS, WISTAR;

ANIMALIA; BACTERIA (MICROORGANISMS); LACTOCOCCUS LACTIS; RATTUS; RODENTIA;

EID: 77953807874     PISSN: 08999007     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nut.2009.06.023     Document Type: Article

References (41)

1. Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. Lancet 1991, 338:131-137. MRC Vitamin Study Research Group.
2. Boushey C.J., Beresford S.A., Omenn G.S., Motulsky A.G. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes. JAMA 1995, 274:1049-1057.
3. Czeizel A.E., Dudas I. Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. N Engl J Med 1992, 327:1832-1835.
4. Danesh J., Lewington S. Plasma homocysteine and coronary heart disease: systematic review of published epidemiological studies. J Cardiovasc Risk 1998, 5:229-232.
5. Herbert V. Biochemical and hematologic lesions in folic acid deficiency. Am J Clin Nutr 1967, 20:562-572.
6. Hines J.D., Halsted C.H., Griggs R.C., Harris J.W. Megaloblastic anemia secondary to folate deficiency associated with hypothyroidism. Ann Intern Med 1968, 68:792-805.
7. Ma J., Stampfer M.J., Giovannucci E., Artigas C., Hunter D.J., Fuchs C., et al. Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer. Cancer Res 1997, 57:1098-1102.
8. Konings E.J., Roomans H.H., Dorant E., Goldbohm R.A., Saris W.H., van den Brandt P.A. Folate intake of the Dutch population according to newly established liquid chromatography data for foods. Am J Clin Nutr 2001, 73:765-776.
9. O'Brien M.M., Kiely M., Harrington K.E., Robson P.J., Strain J.J., Flynn A. The North/South Ireland Food Consumption Survey: vitamin intakes in 18-64-year-old adults. Public Health Nutr 2001, 4:1069-1079.
10. Morris M.C., Tangney C.C. Is dietary intake of folate too low?. Lancet 2007, 369:166-167.
11. Scott J.M. Folate and vitamin B12. Proc Nutr Soc 1999, 58:441-448.
12. Haberg S.E., London S.J., Stigum H., Nafstad P., Nystad W. Folic acid supplements in pregnancy and early childhood respiratory health. Arch Dis Child. 2009, 94:180-184.
13. Sauberlich H.E., Kretsch M.J., Skala J.H., Johnson H.L., Taylor P.C. Folate requirement and metabolism in nonpregnant women. Am J Clin Nutr 1987, 46:1016-1028.
14. McNulty H., Pentieva K. Folate bioavailability. Proc Nutr Soc 2004, 63:529-536.
15. Wang T.T., Reisenauer A.M., Halsted C.H. Comparison of folate conjugase activities in human, pig, rat and monkey intestine. J Nutr 1985, 115:814-819.
16. Gregory J.F. The bioavailability of folate. Folates in health and disease 1995, 195-235. Marcel Dekker, New York. L.B. Bailey (Ed.).
17. Melse-Boonstra A., West C.E., Katan M.B., Kok F.J., Verhoef P. Bioavailability of heptaglutamyl relative to monoglutamyl folic acid in healthy adults. Am J Clin Nutr 2004, 79:424-429.
18. Lin M.Y., Young C.M. Folate levels in cultures of lactic acid bacteria. Int Dairy J 2000, 10:409-413.
19. Sybesma W., Starrenburg M., Tijsseling L., Hoefnagel M.H., Hugenholtz J. Effects of cultivation conditions on folate production by lactic acid bacteria. Appl Environ Microbiol 2003, 69:4542-4548.
20. Sybesma W., Starrenburg M., Kleerebezem M., Mierau I., de Vos W.M., Hugenholtz J. Increased production of folate by metabolic engineering of Lactococcus lactis. Appl Environ Microbiol 2003, 69:3069-3076.
21. Wegkamp A., van Oorschot W., de Vos W.M., Smid E.J. Characterization of the role of para-aminobenzoic acid biosynthesis in folate production by Lactococcus lactis. Appl Environ Microbiol 2007, 73:2673-2681.
22. Wegkamp A., Starrenburg M., de Vos W.M., Hugenholtz J., Sybesma W. Transformation of folate-consuming Lactobacillus gasseri into a folate producer. Appl Environ Microbiol 2004, 70:3146-3148.
23. Sybesma W., Van Den Born E., Starrenburg M., Mierau I., Kleerebezem M., De Vos W.M., Hugenholtz J. Controlled modulation of folate polyglutamyl tail length by metabolic engineering of Lactococcus lactis. Appl Environ Microbiol 2003, 69:7101-7107.
24. Terzaghi B.E., Sandine W.E. Improved medium for lactic streptococci and their bacteriophages. Appl Microbiol 1975, 29:807-813.
25. Horne D.W., Patterson D. Lactobacillus casei microbiological assay of folic acid derivatives in 96-well microtiter plates. Clin Chem 1988, 34:2357-2359.
26. Clifford A.J., Wilson D.S., Bills N.D. Repletion of folate-depleted rats with an amino acid-based diet supplemented with folic acid. J Nutr 1989, 119:1956-1961.
27. Herbert V., Bertino J.R. Folic acid. The vitamins 1967, 243-276. Academic Press, New York. P. Gryorgy (Ed.).
28. Cuskelly G.J., McNulty H., Scott J.M. Effect of increasing dietary folate on red-cell folate: implications for prevention of neural tube defects. Lancet 1996, 347:657-659.
29. Clifford A.J., Jones A.D., Bills N.D. Bioavailability of folates in selected foods incorporated into amino acid-based diets fed to rats. J Nutr 1990, 120:1640-1647.
30. Walzem R.L., Clifford A.J. Folate deficiency in rats fed diets containing free amino acids or intact proteins. J Nutr 1988, 118:1089-1096.
31. Brouwer I.A., van Dusseldorp M., West C.E., Meyboom S., Thomas C.M., Duran M., et al. Dietary folate from vegetables and citrus fruit decreases plasma homocysteine concentrations in humans in a dietary controlled trial. J Nutr 1999, 129:1135-1139.
32. Klijn N., Weerkamp A.H., de Vos W.M. Genetic marking of Lactococcus lactis shows its survival in the human gastrointestinal tract. Appl Environ Microbiol 1995, 61:2771-2774.
33. Drouault S., Corthier G., Ehrlich S.D., Renault P. Survival, physiology, and lysis of Lactococcus lactis in the digestive tract. Appl Environ Microbiol 1999, 65:4881-4886.
34. LeBlanc J.G., Burgess C., Sesma F., de Giori G.S., van Sinderen D. Lactococcus lactis is capable of improving the riboflavin status in deficient rats. Br J Nutr 2005, 94:262-267.
35. LeBlanc J.G., Burgess C., Sesma F., Savoy de Giori G., van Sinderen D. Ingestion of milk fermented by genetically modified Lactococcus lactis improves the riboflavin status of deficient rats. J Dairy Sci 2005, 88:3435-3442.
36. LeBlanc J.G., Rutten G., Bruinenberg P., Sesma F., de Giori G.S., Smid E.J. A novel dairy product fermented with Propionibacterium freudenreichii improves the riboflavin status of deficient rats. Nutrition 2006, 22:645-651.
37. Crittenden R.G., Martinez N.R., Playne M.J. Synthesis and utilisation of folate by yoghurt starter cultures and probiotic bacteria. Int J Food Microbiol 2003, 80:217-222.
38. Holasova M., Fiedlerova V., Roubal P., Pechacova M. Biosynthesis of folates by lactic acid bacteria and propionibacteria in fermented milk. Czech J Food Sci 2004, 22:175-181.
39. Pompei A., Cordisco L., Amaretti A., Zanoni S., Matteuzzi D., Rossi M. Folate production by bifidobacteria as a potential probiotic property. Appl Environ Microbiol 2007, 73:179-185.
40. Hugenholtz J., Hunik J., Santos H., Smid E. Nutraceutical production by propionibacteria. Lait 2002, 82:103-112.
41. Pompei A., Cordisco L., Amaretti A., Zanoni S., Raimondi S., Matteuzzi D., Rossi M. Administration of folate-producing bifidobacteria enhances folate status in Wistar rats. J Nutr 2007, 137:2742-2746.