Prevention of renal interstitial fibrosis via histone deacetylase inhibition in rats with unilateral ureteral obstruction

Transplant Immunology

Volumn 23, Issue 1-2, 2010, Pages 18-23

  Kinugasa, Fumitaka ^a   Noto, Takahisa ^a   Matsuoka, Hideaki ^b   Urano, Yasuharu ^a   Sudo, Yuji ^a   Takakura, Shoji ^a   Mutoh, Seitaro ^a  

^a ASTELLAS PHARMA INC   (Japan)

^b ASTELLAS PHARMA GLOBAL DEVELOPMENT   (United States)

Author keywords

Histone deacetylase inhibitor; Renal interstitial fibrosis; Unilateral ureteral obstruction

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 1ALPHA1; FR 276457; HISTONE DEACETYLASE INHIBITOR; HYDROXYPROLINE; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; UNCLASSIFIED DRUG; FR276457; HYDROXAMIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE COURSE; DISEASE MODEL; DRUG EFFECT; ENZYME INHIBITION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VITRO STUDY; KIDNEY FIBROSIS; KIDNEY INJURY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; URETER OBSTRUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; FIBROSIS; KIDNEY; KIDNEY TRANSPLANTATION; METABOLISM; NEPHRITIS, INTERSTITIAL; PATHOLOGY; SPRAGUE DAWLEY RAT; TUMOR CELL LINE; URETERAL OBSTRUCTION;

ANIMALS; CELL LINE, TUMOR; CHEMOKINE CCL2; DISEASE MODELS, ANIMAL; FIBROSIS; HISTONE DEACETYLASE INHIBITORS; HYDROXAMIC ACIDS; KIDNEY; KIDNEY TRANSPLANTATION; MALE; NEPHRITIS, INTERSTITIAL; RATS; RATS, SPRAGUE-DAWLEY; URETERAL OBSTRUCTION;

EID: 77953806859     PISSN: 09663274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.trim.2010.02.003     Document Type: Article

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