Type 7 adenylyl cyclase-mediated hypothalamic-pituitary-adrenal axis responsiveness: Influence of ethanol and sex

Journal of Pharmacology and Experimental Therapeutics

Volumn 334, Issue 1, 2010, Pages 44-52

  Pronko, Sergey P ^a   Saba, Laura M ^a   Hoffman, Paula L ^a   Tabakoff, Boris ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; ADENYLATE CYCLASE 7; ALCOHOL; CORTICOSTERONE; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR RECEPTOR 1; MESSENGER RNA; UNCLASSIFIED DRUG;

ALCOHOL BLOOD LEVEL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; FEMALE; GENE EXPRESSION; GENOTYPE; HORMONE BLOOD LEVEL; HYPOPHYSIS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMMUNOBLOTTING; MALE; MICROARRAY ANALYSIS; MOUSE; NERVOUS TISSUE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEX DIFFERENCE;

ADENYLATE CYCLASE; ADRENOCORTICOTROPIC HORMONE; ANIMALS; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CORTICOSTERONE; ETHANOL; FEMALE; HUMANS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; IMMUNOBLOTTING; MALE; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; PITUITARY-ADRENAL SYSTEM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEX CHARACTERISTICS;

EID: 77953789738     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.110.166793     Document Type: Article

References (39)

1. Affymetrix (2001) Statistical Algorithms Reference Guide, Affymetrix, Inc., Santa Clara, CA.
2. Aguilera G, Harwood JP, Wilson JX, Morell J, Brown JH, and Catt KJ (1983) Mechanisms of action of corticotropin-releasing factor and other regulators of corticotropin release in rat pituitary cells. J Biol Chem 258:8039-8045. (Pubitemid 13075271)
3. Aguilera G, Wynn PC, Harwood JP, Hauger RL, Millan MA, Grewe C, and Catt KJ (1986) Receptor-mediated actions of corticotropin-releasing factor in pituitary gland and nervous system. Neuroendocrinology 43:79-88. (Pubitemid 16122194)
4. Antoni FA, Palkovits M, Simpson J, Smith SM, Leitch AL, Rosie R, Fink G, and Paterson JM (1998) Ca2+/calcineurin-inhibited adenylyl cyclase, highly abundant in forebrain regions, is important for learning and memory. J Neurosci 18:9650-9661.
5. Antoni FA, Sosunov AA, Haunso A, Paterson JM, and Simpson J (2003) Short-term plasticity of cyclic adenosine 3,5-monophosphate signaling in anterior pituitary corticotrope cells: the role of adenylyl cyclase isotypes. Mol Endocrinol 17:692-703.
6. Benjamini Y and Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc Ser B 57:289-300.
7. Carter RN, Paterson JM, Tworowska U, Stenvers DJ, Mullins JJ, Seckl JR, and Holmes MC (2009) Hypothalamic-pituitary-adrenal axis abnormalities in response to deletion of 11-HSD1 is strain-dependent. J Neuroendocrinol 21:879-887.
8. Cumbay MG and Watts VJ (2004) Novel regulatory properties of human type 9 adenylate cyclase. J Pharmacol Exp Ther 310:108-115.
9. De Souza EB (1995) Corticotropin-releasing factor receptors: physiology, pharmacology, biochemistry and role in central nervous system and immune disorders. Psychoneuroendocrinology 20:789-819.
10. Grigoriadis DE, Heroux JA, and De Souza EB (1993) Characterization and regulation of corticotropin-releasing factor receptors in the central nervous, endocrine and immune systems. Ciba Found Symp 172:85-101, discussion 101-107.
11. Hellevuo K, Welborn R, Menninger JA, and Tabakoff B (1997) Human adenylyl cyclase type 7 contains polymorphic repeats in the 3′ untranslated region: investigations of association with alcoholism. Am J Med Genet 74:95-98.
12. Hines LM, Hoffman PL, Bhave S, Saba L, Kaiser A, Snell L, Goncharov I, LeGault L, Dongier M, Grant B, et al. (2006) A sex-specific role of type VII adenylyl cyclase in depression. J Neurosci 26:12609-12619.
13. Irizarry RA, Hobbs B, Collin F, Beazer-Barclay YD, Antonellis KJ, Scherf U, and Speed TP (2003) Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4:249-264.
14. Lee S, Selvage D, Hansen K, and Rivier C (2004) Site of action of acute alcohol administration in stimulating the rat hypothalamic-pituitary-adrenal axis: comparison between the effect of systemic and intracerebroventricular injection of this drug on pituitary and hypothalamic responses. Endocrinology 145:4470-4479.
15. Levene H (1960) Robust tests for the equality of variance, in Contributions to Probability and Statistics (Olkin I ed) pp 278-292, Stanford University Press, Palo Alto, CA.
16. Li Z, Kang SS, Lee S, and Rivier C (2005) Effect of ethanol on the regulation of corticotropin-releasing factor (CRF) gene expression. Mol Cell Neurosci 29:345-354.
17. Livak KJ and Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25:402-408.
18. Lolait SJ, Stewart LQ, Jessop DS, Young WS 3rd, and O'Carroll AM (2007) The hypothalamic-pituitary-adrenal axis response to stress in mice lacking functional vasopressin V1b receptors. Endocrinology 148:849-856.
19. MacEwan DJ, Kim GD, and Milligan G (1996) Agonist regulation of adenylate cyclase activity in neuroblastoma x glioma hybrid NG108-15 cells transfected to co-express adenylate cyclase type II and the β2-adrenoceptor. Evidence that adenylate cyclase is the limiting component for receptor-mediated stimulation of adenylate cyclase activity. Biochem J 318:1033-1039. (Pubitemid 126740280)
20. Mitchell A and O'Keane V (1998) Steroids and depression. BMJ 316:244-245.
21. Mons N, Decorte L, Jaffard R, and Cooper DM (1998) Ca2+-sensitive adenylyl cyclases, key integrators of cellular signalling. Life Sci 62:1647-1652.
22. Nedelman JR, Gibiansky E, and Lau DT (1995) Applying Bailer's method for AUC confidence intervals to sparse sampling. Pharm Res 12:124-128.
23. Nelson EJ, Hellevuo K, Yoshimura M, and Tabakoff B (2003) Ethanol-induced phosphorylation and potentiation of the activity of type 7 adenylyl cyclase. Involvement of protein kinase Cδ. J Biol Chem 278:4552-4560.
24. Ogilvie K, Lee S, and Rivier C (1997) Effect of three different modes of alcohol administration on the activity of the rat hypothalamic-pituitary-adrenal axis. Alcohol Clin Exp Res 21:467-476. (Pubitemid 27217191)
25. Pfohl B, Sherman B, Schlechte J, and Winokur G (1985) Differences in plasma ACTH and cortisol between depressed patients and normal controls. Biol Psychiatry 20:1055-1072.
26. Rabbani M, Nelson EJ, Hoffman PL, and Tabakoff B (1999) Role of protein kinase C in ethanol-induced activation of adenylyl cyclase. Alcohol Clin Exp Res 23:77-86. (Pubitemid 29068469)
27. Reed B, Varon J, Chait BT, and Kreek MJ (2009) Carbon dioxide-induced anesthesia results in a rapid increase in plasma levels of vasopressin. Endocrinology 150:2934-2939.
28. Rivier C (1996) Alcohol stimulates ACTH secretion in the rat: mechanisms of action and interactions with other stimuli. Alcohol Clin Exp Res 20:240-254.
29. Rivier C, Bruhn T, and Vale W (1984) Effect of ethanol on the hypothalamicpituitary-adrenal axis in the rat: role of corticotropin-releasing factor (CRF). J Pharmacol Exp Ther 229:127-131. (Pubitemid 14082921)
30. Saba L, Bhave SV, Grahame N, Bice P, Lapadat R, Belknap J, Hoffman PL, and Tabakoff B (2006) Candidate genes and their regulatory elements: alcohol preference and tolerance. Mamm Genome 17:669-688.
31. Sobel DO (1985) Role of cyclic AMP in corticotropin releasing factor mediated ACTH release. Peptides 6:591-595.
32. Tabakoff B, Jafee RC, and Ritzmann RF (1978) Corticosterone concentrations in mice during ethanol drinking and withdrawal. J Pharm Pharmacol 30:371-374. (Pubitemid 8350931)
33. Tabakoff B, Nelson E, Yoshimura M, Hellevuo K, and Hoffman PL (2001) Phosphorylation cascades control the actions of ethanol on cell cAMP signalling. J Biomed Sci 8:44-51.
34. Tabakoff B, Saba L, Kechris K, Hu W, Bhave SV, Finn DA, Grahame NJ, and Hoffman PL (2008) The genomic determinants of alcohol preference in mice. Mamm Genome 19:352-365.
35. Thiagarajan AB, Mefford IN, and Eskay RL (1988) Acute effect of intragastric ethanol administration on plasma levels of stress hormones. Adv Alcohol Subst Abuse 7:227-230. (Pubitemid 19083407)
36. Vreeburg SA, Hoogendijk WJ, van Pelt J, Derijk RH, Verhagen JC, van Dyck R, Smit JH, Zitman FG, and Penninx BW (2009) Major depressive disorder and hypothalamic-pituitary-adrenal axis activity: results from a large cohort study. Arch Gen Psychiatry 66:617-626.
37. Wynn PC, Harwood JP, Catt KJ, and Aguilera G (1985) Regulation of corticotropinreleasing factor (CRF) receptors in the rat pituitary gland: effects of adrenalectomy on CRF receptors and corticotroph responses. Endocrinology 116:1653-1659.
38. Yoshimura M and Tabakoff B (1995) Selective effects of ethanol on the generation of cAMP by particular members of the adenylyl cyclase family. Alcohol Clin Exp Res 19:1435-1440.
39. Yoshimura M, Wu PH, Hoffman PL, and Tabakoff B (2000) Overexpression of type 7 adenylyl cyclase in the mouse brain enhances acute and chronic actions of morphine. Mol Pharmacol 58:1011-1016.