Antimicrobial central venous catheters in oncology: Efficacy of a rifampicin-miconazole-releasing catheter

Anticancer Research

Volumn 30, Issue 4, 2010, Pages 1353-1358

  Schierholz, Jörg Michael ^a   Nagelschmidt, Klaus ^b   Nagelschmidt, Manfred ^b   Lefering, Rolf ^c   Yücel, Nedim ^a   Beuth, Josef ^b  

^a University Hospital of Cologne ^*  (Germany)

^b UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^c UNIVERSITY OF WITTEN HERDECKE   (Germany)

Author keywords

Catheter colonization; Local infection; Long term activity; Oncology patients; Rifampicin miconazole releasing catheters

Indexed keywords

MICONAZOLE; RIFAMPICIN;

ADULT; AGED; ANTIMICROBIAL ACTIVITY; ARTICLE; CANCER PATIENT; CATHETER INFECTION; CENTRAL VENOUS CATHETER; CONTROLLED STUDY; FEMALE; HIGH RISK PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; MICROBIAL COLONIZATION; OBESITY; PRIORITY JOURNAL; SKIN INFECTION; SURGICAL PATIENT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIBIOTICS, ANTITUBERCULAR; ANTIFUNGAL AGENTS; BACTERIAL INFECTIONS; CATHETERIZATION, CENTRAL VENOUS; CATHETERS, INDWELLING; COATED MATERIALS, BIOCOMPATIBLE; EQUIPMENT CONTAMINATION; FEMALE; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; HUMANS; MALE; MICONAZOLE; MIDDLE AGED; MYCOSES; NEOPLASMS; RIFAMPIN; RISK FACTORS; YOUNG ADULT;

EID: 77953776080     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Velasco E, Thuler LC, Martins CA, Dias LM and Gonçalves VM: Nosocomial infections in an oncology intensive care unit. Am J Infect Control 25: 458-462, 1997.
2. Spanik S, Kukuckova E, Pichna P, Grausova S, Krupova I, Rusnakova V, Kralovicova K, Krchnakova A, Mrazova M, Lacka J, Koren P, Stopkova K, Nogova J, Demitrovicova A, Helpianska L and Krcmery V Jr: Analysis of 553 episodes of monomicrobial bacteraemia in cancer patients: any association between risk factors and outcome to particular pathogen? Support Care Cancer 5: 330-333, 1997.
3. Bishop L, Dougherty L, Bodenham A, Mansi J, Crowe P, Kibbler C, Shannon M and Treleaven J: Guidelines on the insertion and management of central venous access devices in adults. Int J Lab Hematol 29: 261-278, 2007.
4. Maki DG, Kluger DM and Crnich CJ: The risk of bloodstream infection in adults with different intravascular devices: a systematic review of 200 published prospective studies. Mayo Clin Proc 81: 1159-1171, 2006.
5. Vlasveld LT, Rodenhuis S, Rutgers EJ, Dubbelman AC, Hilton AM, Batchelor D and Rankin EM: Catheter-related complications in 52 patients treated with continuous infusion of low-dose recombinant interleukin-2 via an implanted central venous catheter. Eur J Surg Oncol 20: 122-129, 1994.
6. Rotstein C, Bow EJ, Laverdiere M, Ioannou S, Carr D and Moghaddam N: Randomized placebo-controlled trial of fluconazole prophylaxis for neutropenic cancer patients: benefit based on purpose and intensity of cytotoxic therapy. The Canadian Fluconazole Prophylaxis Study Group. Clin Infect Dis 28: 331-340, 1999.
7. Lemmers NW, Gels ME, Sleijfer DT, Plukker JT, van der Graaf WT, de Langen ZJ, Droste JH, Koops HS and Hoekstra HJ: Complications of venous access ports in 132 patients with disseminated testicular cancer treated with polychemotherapy. J Clin Oncol 14: 2916-2922, 1996.
8. Yücel N, Lefering R, Maegele M, Max M, Rossaint R, Koch A, Schwarz R, Korenkov M, Beuth J, Bach A, Schierholz J, Pulverer G and Neugebauer EA: Reduced colonization and infection with miconazole-rifampicin modified central venous catheters: a randomized controlled clinical study. J Antimicrob Chemother 54: 1109-1115, 2004.
9. Schierholz JM, Fleck C, Beuth J and Pulverer G: The antimicrobial efficacy of a new central venous catheter with long-term broad-spectrum activity. J Antimicrob Chemother 46: 45-50, 2000. (Pubitemid 30466194)
10. Maki DG, Weise CE and Sarafin HW: A semiquantitative culture method for identifying intravenous catheter-related infection. N Engl J Med 296: 1305-1309, 1977. (Pubitemid 8103695)
11. Sherertz RJ, Carruth WA, Hampton AA, Byron MP and Solomon DD: Efficacy of antibiotic-coated catheters in preventing subcutaneous Staphylococcus aureus infection in rabbits. J Inf Dis 167: 98-106, 1993.
12. Marra AR, Opilla M, Edmond MB and Kirby DF: Epidemiology of bloodstream infections in patients receiving long-term total parenteral nutrition. J Clin Gastroenterol 41: 19-28, 2007.
13. Maki DG: Pathogenesis, prevention, and management of infections due to intravascular devices used for infusion therapy. In: Infections Associated with Indwelling Medical Devices. Bisno AL and Waldvogel FA (eds.). Washington: American Society of Microbiology, pp. 161-177, 1989.
14. Pittet D and Wenzel RP: Nosocomial bloodstream infections in the critically III. JAMA 272: 1819-1820, 1994.
15. Jarvis WR, Edwards JR, Culver DH, Hughes JM, Horan T, Emori TG, Banerjee S, Toison J, Henderson T and Gaynes RP: Nosocomial infection rates in adult and pediatric intensive care units in the United States. National Nosocomial Infections SurveUlance System. Am J Med 16: 185S-191S, 1991.
16. Schierholz J, Lefering R, Neugebauer E, Beuth J, König DP and Pulverer G: Central venous catheters and bloodstream infection. JAMA 283: 477-478, 2000.
17. Jones BM, Geary I, Lee ME and Duerden BI: Comparison of the in vitro activities of fenticonazole, other imidazoles, metronidazole, and tetracycline against organisms associated with bacterial vaginosis and skin infections. Antimicrob Agents Chemother 33: 970-972, 1989.
18. van Rooden CJ, Schippers EF, Barge RM, Rosendaal FR, Guiot HF, van der Meer FJ, Meinders AE and Huisman MV: Infectious complications of central venous catheters increase the risk of catheter-related thrombosis in hematology patients: a prospective study. J Clin Oncol 23: 2655-2660, 2005.
19. Steinhilber D, Jaschonek K, Knospe J, Morof O and Roth HJ: Effects of novel antifungal azole derivatives on the 5-lipoxygenase and cyclooxygenase pathway. Arzneimittelforschung 40: 1260-1263, 1990.
20. Falagas ME, Fragoulis K, Bliziotis IA and Chatzinikolaou I: Rifampicin-impregnated central venous catheters: a meta-analysis of randomized controlled trials. J Antimicrob Chemother 59: 359-369, 2007.
21. Raad I, Darouiche R, Dupuis J, Abi-Said D, Gabrielli A, Hachem R, Wall M, Harris R, Jones J, Buzaid A, Robertson C, Shenaq S, Curling P, Burke T and Ericsson C: Central venous catheters coated with minocycline and rifampin for the prevention of catheter-related colonization and bloodstream infections. A randomized, double-blind trial. The Texas Medical Center Catheter Study Group. Ann Intern Med 127: 267-274, 1997.
22. Darouiche RO, Raad II, Heard SO, Thornby JI, Wenker OC, Gabrielli A, Berg J, Khardori N, Hanna H, Hachem R, Harris RL and Mayhall G: A comparison of two antimicrobial-impregnated central venous catheters. Catheter Study Group. N Engl J Med 340: 1-8, 1999.
23. Chatzinikolaou I, Finkel K, Hanna H, Boktour M, Foringer J, Ho T and Raad I: Antibiotic-coated hemodialysis catheters for the prevention of vascular catheter-related infections: a prospective, randomized study. Am J Med 115: 352-357, 2003.
24. León C, Ruiz-Santana S, Rello J, de la Torre MV, Vallès J, Alvarez-Lerma F, Sierra R, Saavedra P and Alvarez-Salgado F: Cabana Study Group: Benefits of minocycline and rifampin-impregnated central venous catheters. A prospective, randomized, double-blind, controlled, multicenter trial. Intensive Care Med 30: 1891-1899, 2004.
25. Darouiche RO, Berger DH, Khardori N, Robertson CS, Wall MJ Jr, Metzler MH, Shah S, Mansouri MD, Cerra-Stewart C, Versalovic J, Reardon MJ and Raad II: Comparison of antimicrobial impregnation with tunneling of long-term central venous catheters: a randomized controlled trial. Ann Surg 242: 193-200, 2005.
26. Fraenkel D, Rickard C, Thomas P, Faoagali J, George N and Ware R: A prospective, randomized trial of rifampicin-minocycline-coated and silver-platinum-carbon-impregnated central venous catheters. Crit Care Med 34: 668-675, 2006.
27. Lorente L, Lecuona M, Ramos MJ, Jimenenz A, Mora ML and Sierra A: The use of rifampicin-miconazole-impregnated catheters reduces the incidence of femoral and jugular catheter-related bacteremia. Clin Infect Dis 47: 1171-1175, 2008.