Increased mortality and morbidity in mild primary hyperparathyroid patients. the Parathyroid Epidemiology and Audit Research Study (PEARS)

Clinical Endocrinology

Volumn 73, Issue 1, 2010, Pages 30-34

  Yu, Ning ^a   Donnan, Peter T ^a   Flynn, Robert W V ^b   Murphy, Michael J ^a   Smith, David ^a   Rudman, Andrew ^a   Leese, Graham P ^c  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b Medical Sciences   (United Kingdom)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CARDIOVASCULAR DISEASE; CAUSE OF DEATH; CEREBROVASCULAR DISEASE; COMORBIDITY; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE SEVERITY; FEMALE; FRACTURE; GLAUCOMA; GROUPS BY AGE; HUMAN; HYPERTENSION; KIDNEY FAILURE; MAJOR CLINICAL STUDY; MALE; MENTAL DISEASE; MORBIDITY; MORTALITY; NEOPLASM; NEPHROLITHIASIS; PARKINSON DISEASE; PRIMARY HYPERPARATHYROIDISM; PRIORITY JOURNAL; RISK FACTOR; SEX DIFFERENCE; BLOOD; CARDIOVASCULAR DISEASES; CEREBROVASCULAR DISORDERS; FRACTURES, BONE; HYPERPARATHYROIDISM, PRIMARY; MIDDLE AGED; RETROSPECTIVE STUDY; UNITED KINGDOM;

CALCIUM;

ADULT; AGED; CALCIUM; CARDIOVASCULAR DISEASES; CEREBROVASCULAR DISORDERS; COMORBIDITY; FEMALE; FRACTURES, BONE; HUMANS; HYPERPARATHYROIDISM, PRIMARY; MALE; MIDDLE AGED; MORBIDITY; RETROSPECTIVE STUDIES; SCOTLAND;

EID: 77953771798     PISSN: 03000664     EISSN: 13652265     Source Type: Journal    
DOI: 10.1111/j.1365-2265.2009.03766.x     Document Type: Article

References (32)

1. Hedback, G., Oden, A., Hedback, G. et al. (1998) Death risk factor analysis in primary hyperparathyroidism. European Journal of Clinical Investigation, 28, 1011 1018. (Pubitemid 29050136)
2. Hedback, G., Oden, A. Tisell, L.E. (1991) The influence of surgery on the risk of death in patients with primary hyperparathyroidism. World Journal of Surgery, 15, 399 405 discussion 406-407.
3. Hedback, G., Tisell, L.E., Bengtsson, B.A. et al. (1990) Premature death in patients operated on for primary hyperparathyroidism. World Journal of Surgery, 14, 829 835 discussion 836.
4. Lundgren, E., Lind, L., Palmer, M. et al. (2001) Increased cardiovascular mortality and normalized serum calcium in patients with mild hypercalcemia followed up for 25 years. Surgery, 130, 978 985.
5. Nilsson, I.L., Yin, L., Lundgren, E. et al. (2002) Clinical presentation of primary hyperparathyroidism in Europe - nationwide cohort analysis on mortality from nonmalignant causes. Journal of Bone and Mineral Research, 17 (Suppl. 2 N68 N74.
6. Nilsson, I.L., Zedenius, J., Yin, L. et al. (2007) The association between primary hyperparathyroidism and malignancy: nationwide cohort analysis on cancer incidence after parathyroidectomy. Endocrine-Related Cancer, 14, 135 140.
7. Ogard, C.G., Engholm, G., Almdal, T.P. et al. (2004) Increased mortality in patients hospitalized with primary hyperparathyroidism during the period 1977-1993 in Denmark. World Journal of Surgery, 28, 108 111.
8. Palmer, M., Adami, H.O., Bergstrom, R. et al. (1987) Mortality after surgery for primary hyperparathyroidism: a follow-up of 441 patients operated on from 1956 to 1979. Surgery, 102, 1 7.
9. Palmer, M., Adami, H.O., Bergstrom, R. et al. (1987) Survival and renal function in untreated hypercalcaemia. Population-based cohort study with 14 years of follow-up. Lancet, 1, 59 62.
10. Ronni-Sivula, H. (1985) Causes of death in patients previously operated on for primary hyperparathyroidism. Annales Chirurgiae et Gynaecologiae, 74, 13 18. (Pubitemid 15101310)
11. Walgenbach, S., Hommel, G. Junginger, T. (2000) Outcome after surgery for primary hyperparathyroidism: ten-year prospective follow-up study. World Journal of Surgery, 24, 564 569 discussion 569-570.
12. Silverberg, S.J. Bilezikian, J.P. (1996) Evaluation and management of primary hyperparathyroidism. Journal of Clinical Endocrinology and Metabolism, 81, 2036 2040.
13. Wermers, R.A., Khosla, S., Atkinson, E.J. et al. (1998) Survival after the diagnosis of hyperparathyroidism: a population-based study. American Journal of Medicine, 104, 115 122.
14. Soreide, J.A., van Heerden, J.A., Grant, C.S. et al. (1997) Survival after surgical treatment for primary hyperparathyroidism. Surgery, 122, 1117 1123.
15. Bilezikian, J.P., Khan, A.A. Potts Jr., J.T. (2009) Guidelines for the management of asymptomatic primary hyperparathyroidism: statement from the third international workshop. Journal of Clinical Endocrinology and Metabolism, 94, 335 339.
16. Eastell, R., Arnold, A., Brandi, M.L. et al. (2009) Diagnosis of asymptomatic primary hyperparathyroidism: proceedings of the third international workshop. Journal of Clinical Endocrinology and Metabolism, 94, 340 350.
17. Khan, A., Grey, A. Shoback, D. (2009) Medical management of asymptomatic primary hyperparathyroidism: proceedings of the third international workshop. Journal of Clinical Endocrinology and Metabolism, 94, 373 381.
18. Khan, A.A., Bilezikian, J.P. Potts Jr., J.T. (2009) The diagnosis and management of asymptomatic primary hyperparathyroidism revisited. Journal of Clinical Endocrinology and Metabolism, 94, 333 334.
19. Silverberg, S.J., Lewiecki, E.M., Mosekilde, L. et al. (2009) Presentation of asymptomatic primary hyperparathyroidism: proceedings of the third international workshop. Journal of Clinical Endocrinology and Metabolism, 94, 351 365.
20. Udelsman, R., Pasieka, J.L., Sturgeon, C. et al. (2009) Surgery for asymptomatic primary hyperparathyroidism: proceedings of the third international workshop. Journal of Clinical Endocrinology and Metabolism, 94, 366 372.
21. HIC. Health Informatics Centre, University of Dundee. http://www.dundee.ac.uk/hic/.
22. Flynn, R.W., Macdonald, T.M., Jung, R.T. et al. (2006) Mortality and vascular outcomes in patients treated for thyroid dysfunction. Journal of Clinical Endocrinology and Metabolism, 91, 2159 2164.
23. Flynn, R.W., MacDonald, T.M., Morris, A.D. et al. (2004) The thyroid epidemiology, audit, and research study: thyroid dysfunction in the general population. Journal of Clinical Endocrinology and Metabolism, 89, 3879 3884.
24. Leese, G.P., Flynn, R.V., Jung, R.T. et al. (2008) Increasing prevalence and incidence of thyroid disease in Tayside, Scotland: the Thyroid Epidemiology Audit and Research Study (TEARS). Clinical Endocrinology (Oxf), 68, 311 316.
25. Yu, N., Donnan, P., Murphy, M.J. et al. (2009) Epidemiology of primary hyperparathyroidism in Tayside, Scotland, UK. Clinical Endocrinology Oxf 71, 485 493.
26. Wilson, P. (2004) Legal issues of data anonymisation in research. BMJ, 328, 1300 1301.
27. International Classification of Diseases 1977) Manual of the International Classification of Diseases, Injuries and Causes of Death, 9th edn. World Health Organization
28. Goldblatt, P., Moser, K., Fox, J. et al. (1990) Longitudinal Study. Mortality and Social Organisation. HMSO
29. Morris, J.A. Gardner, M.J. (1988) Calculating confidence intervals for relative risks (odds ratios) and standardised ratios and rates. British Medical Journal (Clinical Research Ed.), 296, 1313 1316.
30. Ljunghall, S., Jakobsson, S., Joborn, C. et al. (1991) Longitudinal studies of mild primary hyperparathyroidism. Journal of Bone and Mineral Research, 6 (Suppl. 2 S111 S116 discussion S121-S124.
31. Norenstedt, S., Ekbom, A., Brandt, L. et al. (2009) Postoperative mortality in parathyroid surgery in Sweden during five decades: improved outcome despite older patients. European Journal of Endocrinology, 160, 295 299.
32. Norman, J.G. Politz, D.E. (2007) Safety of immediate discharge after parathyroidectomy: a prospective study of 3,000 consecutive patients. Endocrine Practice, 13, 105 113.