메뉴 건너뛰기




Volumn 2, Issue 2, 2009, Pages 112-117

Cytoplasmic and nuclear accumulation of antisense oligomers incubated as streptavidin delivery nanoparticles

Author keywords

Antisense oligomer; mdr1; Nanoparticle; Nuclear migration; Streptavidin

Indexed keywords

MESSENGER RNA; NANOPARTICLE; OLIGOMER; RHODAMINE 123; STREPTAVIDIN;

EID: 77953769752     PISSN: 18744710     EISSN: None     Source Type: Journal    
DOI: 10.2174/1874471010902020112     Document Type: Article
Times cited : (1)

References (24)
  • 1
    • 33645700779 scopus 로고    scopus 로고
    • The influence of chemical structure of DNA and other oligomer radiopharmaceuticals on tumor delivery
    • Hnatowich, D.J.; Nakamura, K. The influence of chemical structure of DNA and other oligomer radiopharmaceuticals on tumor delivery. Curr. Opin. Mol. Ther., 2006, 8, 136-143.
    • (2006) Curr. Opin. Mol. Ther , vol.8 , pp. 136-143
    • Hnatowich, D.J.1    Nakamura, K.2
  • 2
    • 0033799686 scopus 로고    scopus 로고
    • Preparation and applications of peptideoligonucleotide conjugates
    • Tung, C.H.; Stein, S. Preparation and applications of peptideoligonucleotide conjugates. Bioconjug. Chem., 2000, 11, 605-618.
    • (2000) Bioconjug. Chem , vol.11 , pp. 605-618
    • Tung, C.H.1    Stein, S.2
  • 3
    • 0035207025 scopus 로고    scopus 로고
    • Pharmacokinetics and delivery of tat and tat-protein conjugates to tissues in vivo
    • Lee, H.J.; Partridge, W.M. Pharmacokinetics and delivery of tat and tat-protein conjugates to tissues in vivo. Bioconjug. Chem., 2001,12, 995-999.
    • (2001) Bioconjug. Chem , vol.12 , pp. 995-999
    • Lee, H.J.1    Partridge, W.M.2
  • 4
    • 0036301601 scopus 로고    scopus 로고
    • Imaging gene expression in the brain in vivo in a transgenic mouse model of Huntington's disease with an antisense radiopharmaceutical and drug-targeting technology
    • Lee, H.J.; Boado, R.J.; Braasch, D.A.; Corey, D.R.; Partridge, W.M. Imaging gene expression in the brain in vivo in a transgenic mouse model of Huntington's disease with an antisense radiopharmaceutical and drug-targeting technology. J. Nucl. Med., 2002, 43, 948-956.
    • (2002) J. Nucl. Med , vol.43 , pp. 948-956
    • Lee, H.J.1    Boado, R.J.2    Braasch, D.A.3    Corey, D.R.4    Partridge, W.M.5
  • 5
    • 34547230105 scopus 로고    scopus 로고
    • Addition of TAT, polyarginine and cholesterol carriers to mdr1 antisense DNA using streptavidin as linker [Abstract]
    • Nakamura, K.; Wang, Y.; Liu, X.; Kubo, A.; Hnatowich, D.J. Addition of TAT, polyarginine and cholesterol carriers to mdr1 antisense DNA using streptavidin as linker [Abstract]. J. Nucl. Med. (Suppl), 2006, 47, 512P.
    • (2006) J. Nucl. Med. , vol.47 , Issue.SUPPL. , pp. 512
    • Nakamura, K.1    Wang, Y.2    Liu, X.3    Kubo, A.4    Hnatowich, D.J.5
  • 6
    • 34547161843 scopus 로고    scopus 로고
    • Simplified preparation via streptavidin of antisense oligomers/carriers nanoparticles showing improved cellular delivery in culture
    • Wang, Y.; Nakamura, K.; Liu, X.; Kitamura, N.; Kubo, A.; Hnatowich, D.J. Simplified preparation via streptavidin of antisense oligomers/carriers nanoparticles showing improved cellular delivery in culture. Bioconjug. Chem., 2007, 18, 1338-1343.
    • (2007) Bioconjug. Chem , vol.18 , pp. 1338-1343
    • Wang, Y.1    Nakamura, K.2    Liu, X.3    Kitamura, N.4    Kubo, A.5    Hnatowich, D.J.6
  • 7
    • 38349019841 scopus 로고    scopus 로고
    • Cell studies of a three-component antisense MORF/tat/Herceptin nanoparticle designed for improved tumor delivery
    • Liu, X.; Wang, Y.; Nakamura, K.; Kubo, A.; Hnatowich, D.J. Cell studies of a three-component antisense MORF/tat/Herceptin nanoparticle designed for improved tumor delivery. Cancer Gene Ther., 2008, 15, 126-132.
    • (2008) Cancer Gene Ther , vol.15 , pp. 126-132
    • Liu, X.1    Wang, Y.2    Nakamura, K.3    Kubo, A.4    Hnatowich, D.J.5
  • 8
    • 36049043872 scopus 로고    scopus 로고
    • Cell culture and xengrafted animal studies of radiolabeled antisense DNA/carrier constructs using streptavidin as linker
    • Nakamura, K.; Wang, Y.; Liu, X.; Kitamura, N.; Kubo, A.; Hnatowich, D.J. Cell culture and xengrafted animal studies of radiolabeled antisense DNA/carrier constructs using streptavidin as linker. J. Nucl. Med., 2007, 48, 1845-1852.
    • (2007) J. Nucl. Med , vol.48 , pp. 1845-1852
    • Nakamura, K.1    Wang, Y.2    Liu, X.3    Kitamura, N.4    Kubo, A.5    Hnatowich, D.J.6
  • 9
    • 77953777015 scopus 로고    scopus 로고
    • The biodistribution in tumored mice of 99mTc labeled antisense MORF/carrier streptavidin nanoparticles
    • Wang, Y.; Liu, X.; Nakamura, K.; Chen, L.; Rusckowski, M.; Hnatowich, D.J. The biodistribution in tumored mice of 99mTc labeled antisense MORF/carrier streptavidin nanoparticles. J. Nucl. Med., 2008, 49(Suppl.), 51-52.
    • (2008) J. Nucl. Med , vol.49 , Issue.SUPPL. , pp. 51-52
    • Wang, Y.1    Liu, X.2    Nakamura, K.3    Chen, L.4    Rusckowski, M.5    Hnatowich, D.J.6
  • 10
    • 77953779264 scopus 로고    scopus 로고
    • Successful radiotherapy of tumor cells using a three-component streptavidin delivery nanoparticle and 111In
    • (in press)
    • Liu, X.; Wang, Y.; Nakamura, K.; Chen, L.; Kawauchi, S.; Rusckowski, M.; Hnatowich, D.J. Successful radiotherapy of tumor cells using a three-component streptavidin delivery nanoparticle and 111In. J. Nucl. Med., (in press).
    • J. Nucl. Med
    • Liu, X.1    Wang, Y.2    Nakamura, K.3    Chen, L.4    Kawauchi, S.5    Rusckowski, M.6    Hnatowich, D.J.7
  • 12
    • 0042786952 scopus 로고    scopus 로고
    • Electrostatic binding with tat and other cationic peptides increases cell accumulation of 99mTc-antisense DNAs without entrapment
    • Zhang, Y.M.; Liu, C.B.; Liu, N.; Ferro, F.G.; He, J.; Rusckowski, M.; Hnatowich, D.J. Electrostatic binding with tat and other cationic peptides increases cell accumulation of 99mTc-antisense DNAs without entrapment. Mol. Imaging Biol., 2003, 5, 240-247.
    • (2003) Mol. Imaging Biol , vol.5 , pp. 240-247
    • Zhang, Y.M.1    Liu, C.B.2    Liu, N.3    Ferro, F.G.4    He, J.5    Rusckowski, M.6    Hnatowich, D.J.7
  • 14
    • 17844397735 scopus 로고    scopus 로고
    • Antisense targeting of pglycoprotein expression in tissue culture
    • Nakamura, K.; Kubo, A.; Hnatowich, D.J. Antisense targeting of pglycoprotein expression in tissue culture. J. Nucl. Med., 2005, 46, 509-13.
    • (2005) J. Nucl. Med , vol.46 , pp. 509-513
    • Nakamura, K.1    Kubo, A.2    Hnatowich, D.J.3
  • 17
    • 34248582937 scopus 로고    scopus 로고
    • An improved synthesis of NHS-MAG3 for conjugation and radiolabeling of biomolecules with 99mTc at room temperature
    • Wang, Y.; Liu, X.; Hnatowich, D.J. An improved synthesis of NHS-MAG3 for conjugation and radiolabeling of biomolecules with 99mTc at room temperature. Nat. Protoc., 2007, 2, 972-978.
    • (2007) Nat. Protoc , vol.2 , pp. 972-978
    • Wang, Y.1    Liu, X.2    Hnatowich, D.J.3
  • 18
    • 0031849610 scopus 로고    scopus 로고
    • Novel chemically modified oligonucleotides provide potent inhibition of P-glycoprotein expression
    • Alahari, S.K.; Delong, R.; Fisher, M.H.; Dean, N.M.; Viliet, P.; Juliano, R.L. Novel chemically modified oligonucleotides provide potent inhibition of P-glycoprotein expression. J. Pharm. Exp. Therapeut., 1998, 286, 419-428.
    • (1998) J. Pharm. Exp. Therapeut , vol.286 , pp. 419-428
    • Alahari, S.K.1    Delong, R.2    Fisher, M.H.3    Dean, N.M.4    Viliet, P.5    Juliano, R.L.6
  • 20
    • 2942585676 scopus 로고    scopus 로고
    • Effective intracellular delivery of oligonucleotides in order to make sense of antisense
    • Shi, F.; Hoekstra, D. Effective intracellular delivery of oligonucleotides in order to make sense of antisense. J. Control Release, 2004,97, 189-209.
    • (2004) J. Control Release , vol.97 , pp. 189-209
    • Shi, F.1    Hoekstra, D.2
  • 22
    • 33645725781 scopus 로고    scopus 로고
    • Influence of two transfectors on delivery of 99mTc antisense DNA in tumor-bearing mice
    • Nakamura, K.; Wang, Y.; Liu, X.; Kubo, A.; Hnatowich, D.J. Influence of two transfectors on delivery of 99mTc antisense DNA in tumor-bearing mice. Mol. Imaging Biol., 2006, 8, 188-192.
    • (2006) Mol. Imaging Biol , vol.8 , pp. 188-192
    • Nakamura, K.1    Wang, Y.2    Liu, X.3    Kubo, A.4    Hnatowich, D.J.5
  • 23
    • 35848939831 scopus 로고    scopus 로고
    • Cationic transfectors increase accumulation in cultured tumor cells of radiolabeled antisense DNAs without entrapment
    • Nakamura, K.; Wang, Y.; Liu, X.; Kubo, A.; Hnatowich, D.J. Cationic transfectors increase accumulation in cultured tumor cells of radiolabeled antisense DNAs without entrapment. Cancer Biother. Radiopharm., 2007, 22, 629-635.
    • (2007) Cancer Biother. Radiopharm , vol.22 , pp. 629-635
    • Nakamura, K.1    Wang, Y.2    Liu, X.3    Kubo, A.4    Hnatowich, D.J.5
  • 24
    • 0031575767 scopus 로고    scopus 로고
    • Specific inhibition of influenza virus RNA polymerase and nucleoprotein genes expression by liposomally endocapsulated antisense phosphorothioate oligonucleotides: Penetration and localization of oligonucleotides in clone 76 cells
    • Hatta, T.; Takai, K.; Nakada, S.; Yokota, T.; Takaku, H. Specific inhibition of influenza virus RNA polymerase and nucleoprotein genes expression by liposomally endocapsulated antisense phosphorothioate oligonucleotides: penetration and localization of oligonucleotides in clone 76 cells. Biochim. Biophy. Res. Comm., 1997,232, 545-549.
    • (1997) Biochim. Biophy. Res. Comm , vol.232 , pp. 545-549
    • Hatta, T.1    Takai, K.2    Nakada, S.3    Yokota, T.4    Takaku, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.