Potential synergy between two renal toxicants: DTPA and uranium;Synergie potentielle entre deux toxiques rénaux: Le DTPA et l'uranium

Radioprotection

Volumn 41, Issue 4, 2006, Pages 413-420

  Muller, D ^a,b   Houpert, P ^a   Henge Napoli, M H ^a,c   Metivier H ^a   Paquet, F ^a  

^a INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE IRSN   (France)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c CEA DEN Valrhô Dir CVAR   (France)

Author keywords

DTPA; in vitro; kidney; toxicity; Uranium

Indexed keywords

DTPA; IN-VITRO; IS ADMINISTRATION; KIDNEY; LETHAL CONCENTRATION; POTENTIAL SYNERGIES; PROXIMAL TUBULES; URANIUM CONCENTRATION;

CELL CULTURE; CYTOTOXICITY; PLUTONIUM; SODIUM; TOXICITY;

URANIUM;

EID: 77953765743     PISSN: 00338451     EISSN: 1769700X     Source Type: Journal    
DOI: 10.1051/radiopro:2006012     Document Type: Article

References (13)

1. Bhattacharyya M.H., Breitenstein B.D., Métivier H., Stradling G.N., Volf V. (1995) Traitement de la contamination interne accidentelle des travailleurs. Rapport IPSN, Fontenay-aux-Roses.
2. Choi J.S., Kim K.R., Ahm D.W., Park Y.S. (1999) Cadmium inhibits albumin endocytosis in opossum kidney epithelial cells, Toxicol. Appl. Pharm. 161, 146-152.
3. Decorti G., Malusà N., Furlan G., Candussio L., Klugmann F.B. (1999) Endocytosis of gentamicin in a proximal tubular renal cell line, Life Sci. 65, 1115-1124.
4. Diamond G.L., Morrow P.E., Panner B.J., Gelein R.M., Baggs R.B. (1989) Reversible uranyl fluride nephrotoxicity in the Long Evans rat. Fund. Appl. Toxicol. 13, 65-78.
5. Doolan P.D., Schwartz S.L., Hayes J.R., Mullen J.C., Cummings N.B. (1967) An evaluation of the nephrotoxicity of ethylenediaminetetraacetate and diethylenetriaminepentaacetate in the rat, Tox. Appl. Pharmacol. 10, 481-500.
6. Dvorak P. (1970) Metabolism and toxicity of therapeutic agents. 8. Excretion of sodium, potassium, magnesium and zinc, Strahlentherapie 139, 611-618.
7. Endo T., Kimura O., Sakata M. (1996) Comparative studies of cadmium and mercury accumulation by LLC-PK1 cells: effects of pH on uptake and efflux, Toxicol. Lett. 87, 77-83.
8. Fritsch P., Herbreteau D., Moutairou K., Lantenois G., Richard-Le Naour H., Grillon G., Hoffschir D., Poncy J.L., Laurent A., Masse R. (1994) Comparative toxicity of 3,4,3-LIHOPO and DTPA in baboons: preliminary results, Radiat. Prot. Dosim. 53, 315-318.
9. Havlicek F. (1967) Metabolism and toxicity of therapeutic chelating agents. 3. Effect of EDTA and DTPA on the excretion of endogenous zinc, Strahlentherapie 134, 296-305.
10. Mirto H., Hengé-Napoli M.H., Gibert R., Ansoborlo E., Fournier M., Cambar J. (1999) Intracellular behaviour of uranium (VI) on renal epithelial cell in culture (LLC-PK1): influence of uranium speciation, Toxicol. Lett. 104, 249-256.
11. Morgan R.M., Smith H. (1974) Histological changes in kidney, liver and duodenum of the mouse following the acute and subacute administration of diethylenetriaminepentaacetic acid, Toxicology 2, 153-163.
12. Takano M., Ohishi Y., Okuda M., Yasuhara M., Hori R. (1994) Transport of gentamincin and fluidphase endocytis markers in the LLC-PK1 kidney epithelial cell line, J. Pharmacol. Exp. Ther. 268, 669-673.
13. Wood R., Sharp C., Gourmelon P., Le Guen B., Stradling G.N., Taylor D.M., Hengé-Napoli M.H. (2000) Decorporation treatment - Medical overview, Radiat. Prot. Dosim. 87, 51-57.