Development of a quantitative and conformation-sensitive ATR-FTIR biosensor for Alzheimer's disease: The effect of deuteration on the detection of the Aβ peptide

Spectroscopy

Volumn 24, Issue 1-2, 2010, Pages 61-66

  Kleiren, Emilie ^a   Ruysschaert, Jean Marie ^a   Goormaghtigh, Erik ^a   Raussens, Vincent ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

Alzheimer's disease; Amyloid peptide; ATR FTIR spectroscopy; Biosensor; Diagnosis

Indexed keywords

ALZHEIMER'S DISEASE; ATR FTIR; ATR-FT-IR SPECTROSCOPY; ATTENUATED TOTAL REFLECTION FOURIER TRANSFORM INFRARED; COGNITIVE DECLINE; DEUTERATED WATER; DEUTERATIONS; DIAGNOSTIC TOOLS; FUNCTIONALIZED; GERMANIUM CRYSTALS; NEUROTOXIC SPECIES; PHYSIOLOGICAL FLUIDS;

BIOSENSORS; CHEMICAL DETECTION; CONFORMATIONS; DEUTERIUM; FOURIER TRANSFORM INFRARED SPECTROSCOPY; FOURIER TRANSFORMS; GERMANIUM; GLYCOPROTEINS; OLIGOMERS; PEPTIDES; WAVELET TRANSFORMS;

DIAGNOSIS;

AMYLOID BETA PROTEIN; BIOLOGICAL MARKER; GERMANIUM; OLIGOMER;

ALZHEIMER DISEASE; ANTIBODY SPECIFICITY; BIOSENSOR; COGNITIVE DEFECT; CONFERENCE PAPER; CORRELATION ANALYSIS; CRYSTAL STRUCTURE; DIAGNOSTIC TEST; EARLY DIAGNOSIS; INFRARED SPECTROSCOPY; PROTEIN AGGREGATION; PROTEIN CONFORMATION; QUANTITATIVE ANALYSIS; RELIABILITY;

EID: 77953765254     PISSN: 07124813     EISSN: None     Source Type: Journal    
DOI: 10.3233/SPE-2010-0405     Document Type: Conference Paper

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