Epitope mapping of ibalizumab, a humanized anti-CD4 monoclonal antibody with Anti-HIV-1 activity in infected patients

Journal of Virology

Volumn 84, Issue 14, 2010, Pages 6935-6942

  Song, Ruijiang ^a   Franco, David ^a   Kao, Chia Ying ^a   Yu, Faye ^a   Huang, Yaoxing ^a   Ho, David D ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CD4 ANTIGEN; CD40 LIGAND MONOCLONAL ANTIBODY; GLYCOPROTEIN GP 120; IBALIZUMAB; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ARTICLE; CONTROLLED STUDY; DRUG BINDING; DRUG MECHANISM; DRUG POTENCY; DRUG SAFETY; EPITOPE MAPPING; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOSUPPRESSIVE TREATMENT; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; ANTI-HIV AGENTS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD4; EPITOPE MAPPING; EPITOPES; HIV INFECTIONS; HIV-1; HUMANS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; PROTEIN CONFORMATION; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT; VIRUS INTERNALIZATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 77953748705     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00453-10     Document Type: Article

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