Deletion of 5q as a rare abnormality in chronic lymphocytic leukemia

Cancer Genetics and Cytogenetics

Volumn 200, Issue 2, 2010, Pages 175-179

  Karakosta, Maria ^a   Tsakiridou, Anastasia ^b   Korantzis, Ioannis ^c   Manola, Kalliopi N ^a  

^a INSTITUTE OF NANOSCIENCE AND NANOTECHNOLOGY   (Greece)

^b UNIVERSITY GENERAL HOSPITAL OF PATRAS   (Greece)

^c PAPAGEORGIOU GENERAL HOSPITAL   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; BONE MARROW BIOPSY; CANCER PATIENT; CASE REPORT; CELL INFILTRATION; CHROMOSOME 5Q; CHROMOSOME ANALYSIS; CHROMOSOME DELETION; CHROMOSOME DELETION 5Q; CHRONIC LYMPHATIC LEUKEMIA; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENETIC ASSOCIATION; HUMAN; HUMAN TISSUE; KARYOTYPING; MALE; PRIORITY JOURNAL; PROGNOSIS;

AGED; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 5; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MALE; MIDDLE AGED;

EID: 77953747161     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cancergencyto.2010.04.002     Document Type: Article

References (11)

1. Auer L.R., Riaz S., Cotter F.E. The 13q and 11q B-cell chronic lymphocytic leukaemia-associated regions derive from a common ancestral region in the zebrafish. Br J Haematol 2007, 137:443-453.
2. Put N., Konings P., Rack K., Jamar M., Van Roy N., Libouton J.M., et al. Improved detection of chromosomal abnormalities in chronic lymphocytic leukemia by conventional cytogenetics using CpG oligonucleotide and interleukin-2 stimulation: a Belgian multicentric study. Genes Chromosomes Cancer 2009, 48:843-853. Belgian Cytogenetic Group for Hemato-Oncology (BCGHO).
3. Buhmann R., Kurzeder C., Rehklau J., Westhaus D., Bursch S., Hiddemann W., et al. CD40L stimulation enhances the ability of conventional metaphase cytogenetics to detect chromosome aberrations in B-cell chronic lymphocytic leukaemia cells. Br J Haematol 2002, 118:968-975.
4. Van den Berghe H., Michaux L. 5q-, twenty-five years later: a synopsis. Cancer Genet Cytogenet 1997, 94:1-7.
5. National Cancer Institute. Cancer Genome Anatomy Project. Available at: Accessed September 29, 2009. http://cgap.nci.nih.gov/Chromosomes/CytList.
6. Barbieri D., Michaux J.L., Bosly A., van Hove W., Noens L., Drochmans A., et al. Cytogenetic evaluation of bone marrow involvement in non-Hodgkin's lymphomas. A survey of 94 cases. Haematologica 1984, 69:285-296.
7. Antosz H., Kitlińska J., Kwiatkowska-Drabik B., Koczkodaj D., Wach M., Antosz M., et al. Rb1 gene expression in B-cell lymphocytic leukaemia cases with deletion in the 13q14 region. Cytobios 1997, 92:111-121.
8. Finn W.G., Kay N.E., Kroft S.H., Church S., Peterson L.C. Secondary abnormalities of chromosome 6q in B-cell chronic lymphocytic leukemia: a sequential study of karyotypic instability in 51 patients. Am J Hematol 1998, 59:223-229.
9. Eisenmann K.M., Dykema K.J., Matheson S.F., Kent N.F., DeWard A.D., West R.A., et al. 5q-myelodysplastic syndromes: chromosome 5q genes direct a tumor-suppression network sensing actin dynamics. Oncogene 2009, 1(28):3429-3441.
10. Huh Y.O., Abruzzo L.V., Rassidakis G.Z., Parry-Jones N., Schlette E., Brito-Bapabulle V., et al. The t(14;19)(q32;q13)-positive small B-cell leukaemia: a clinicopathologic and cytogenetic study of seven cases. Br J Haematol 2007, 136:220-228.
11. Nilsson M., Mertens F., Höglund M., Mandahl N., Panagopoulos I. Truncation and fusion of HMGA2 in lipomas with rearrangements of 5q32→q33 and 12q14→q15. Cytogenet Genome Res 2006, 112:60-66.