메뉴 건너뛰기




Volumn 54, Issue 7, 2010, Pages 2775-2780

Pharmacokinetics of darunavir at 900 milligrams and ritonavir at 100 milligrams once daily when coadministered with efavirenz at 600 milligrams once daily in healthy volunteers

Author keywords

[No Author keywords available]

Indexed keywords

DARUNAVIR; EFAVIRENZ; RITONAVIR; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; BENZOXAZINE DERIVATIVE; SULFONAMIDE;

EID: 77953742463     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01564-09     Document Type: Article
Times cited : (11)

References (21)
  • 3
    • 62649093555 scopus 로고    scopus 로고
    • Pharmacokinetics, efficacy, and safety of darunavir/ritonavir 800/100 mg once-daily in treatment-naive and -experienced patients
    • Boffito, M., D. Miralles, and A. Hill. 2008. Pharmacokinetics, efficacy, and safety of darunavir/ritonavir 800/100 mg once-daily in treatment-naive and -experienced patients. HIV Clin. Trials 9:418-427.
    • (2008) HIV Clin. Trials , vol.9 , pp. 418-427
    • Boffito, M.1    Miralles, D.2    Hill, A.3
  • 5
    • 17144385842 scopus 로고    scopus 로고
    • Intracellular measurements of anti-HIV drugs indinavir, amprenavir, saquinavir, ritonavir, nelfinavir, lopinavir, atazanavir, efavirenz and nevirapine in peripheral blood mononuclear cells by liquid chromatography coupled to tandem mass spectrometry
    • Colombo, S., A. Beguin, A. Telenti, J. Biollaz, T. Buclin, B. Rochat, and L. A. Decosterd. 2005. Intracellular measurements of anti-HIV drugs indinavir, amprenavir, saquinavir, ritonavir, nelfinavir, lopinavir, atazanavir, efavirenz and nevirapine in peripheral blood mononuclear cells by liquid chromatography coupled to tandem mass spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 819:259-276.
    • (2005) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. , vol.819 , pp. 259-276
    • Colombo, S.1    Beguin, A.2    Telenti, A.3    Biollaz, J.4    Buclin, T.5    Rochat, B.6    Decosterd, L.A.7
  • 6
    • 35748933191 scopus 로고    scopus 로고
    • HPLC-MS method for the simultaneous quantification of the new HIV protease inhibitor darunavir, and 11 other antiretroviral agents in plasma of HIV-infected patients
    • D'Avolio, A., M. Siccardi, M. Sciandra, L. Baietto, S. Bonora, L. Trentini, and G. Di Perri. 2007. HPLC-MS method for the simultaneous quantification of the new HIV protease inhibitor darunavir, and 11 other antiretroviral agents in plasma of HIV-infected patients. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 859:234-240.
    • (2007) J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. , vol.859 , pp. 234-240
    • D'Avolio, A.1    Siccardi, M.2    Sciandra, M.3    Baietto, L.4    Bonora, S.5    Trentini, L.6    Di Perri, G.7
  • 7
    • 19544386471 scopus 로고    scopus 로고
    • TMC114, a novel human immunodeficiency virus type 1 protease inhibitor active against protease inhibitor-resistant viruses, including a broad range of clinical isolates
    • De Meyer, S., H. Azijn, D. Surleraux, D. Jochmans, A. Tahri, R. Pauwels, P. Wigerinck, and M. P. de Bethune. 2005. TMC114, a novel human immunodeficiency virus type 1 protease inhibitor active against protease inhibitor-resistant viruses, including a broad range of clinical isolates. Antimicrob. Agents Chemother. 49:2314-2321.
    • (2005) Antimicrob. Agents Chemother. , vol.49 , pp. 2314-2321
    • De Meyer, S.1    Azijn, H.2    Surleraux, D.3    Jochmans, D.4    Tahri, A.5    Pauwels, R.6    Wigerinck, P.7    De Bethune, M.P.8
  • 10
    • 6344240478 scopus 로고    scopus 로고
    • Induction of CYP3A4 by efavirenz in primary human hepatocytes: Comparison with rifampin and phenobarbital
    • Hariparsad, N., S. C. Nallani, R. S. Sane, D. J. Buckley, A. R. Buckley, and P. B. Desai. 2004. Induction of CYP3A4 by efavirenz in primary human hepatocytes: comparison with rifampin and phenobarbital. J. Clin. Pharmacol. 44:1273-1281.
    • (2004) J. Clin. Pharmacol. , vol.44 , pp. 1273-1281
    • Hariparsad, N.1    Nallani, S.C.2    Sane, R.S.3    Buckley, D.J.4    Buckley, A.R.5    Desai, P.B.6
  • 11
    • 12244262297 scopus 로고    scopus 로고
    • Pharmacokinetic-pharmacodynamic analysis of lopinavir-ritonavir in combination with efavirenz and two nucleoside reverse transcriptase inhibitors in extensively pretreated human immunodeficiency virus-infected patients
    • Hsu, A., J. Isaacson, S. Brun, B. Bernstein, W. Lam, R. Bertz, C. Foit, K. Rynkiewicz, B. Richards, M. King, R. Rode, D. J. Kempf, G. R. Granneman, and E. Sun. 2003. Pharmacokinetic-pharmacodynamic analysis of lopinavir-ritonavir in combination with efavirenz and two nucleoside reverse transcriptase inhibitors in extensively pretreated human immunodeficiency virus-infected patients. Antimicrob. Agents Chemother. 47:350-359.
    • (2003) Antimicrob. Agents Chemother. , vol.47 , pp. 350-359
    • Hsu, A.1    Isaacson, J.2    Brun, S.3    Bernstein, B.4    Lam, W.5    Bertz, R.6    Foit, C.7    Rynkiewicz, K.8    Richards, B.9    King, M.10    Rode, R.11    Kempf, D.J.12    Granneman, G.R.13    Sun, E.14
  • 12
    • 7244221529 scopus 로고    scopus 로고
    • Pharmacokinetics of indinavir at 800, 600, and 400 milligrams administered with ritonavir at 100 milligrams and efavirenz in ethnic Chinese patients infected with human immunodeficiency virus
    • Lee, L. S., A. Panchalingam, M. C. Yap, and N. I. Paton. 2004. Pharmacokinetics of indinavir at 800, 600, and 400 milligrams administered with ritonavir at 100 milligrams and efavirenz in ethnic Chinese patients infected with human immunodeficiency virus. Antimicrob. Agents Chemother. 48:4476-4478.
    • (2004) Antimicrob. Agents Chemother. , vol.48 , pp. 4476-4478
    • Lee, L.S.1    Panchalingam, A.2    Yap, M.C.3    Paton, N.I.4
  • 13
    • 77950657842 scopus 로고    scopus 로고
    • Darunavir/ritonavir and efavirenz exert differential effects on MRP1 transporter expression and function in healthy volunteers
    • Lee, L. S., G. H. Soon, P. Shen, E. L. Yong, C. Flexner, and P. Pham. 2010. Darunavir/ritonavir and efavirenz exert differential effects on MRP1 transporter expression and function in healthy volunteers. Antivir. Ther. 15:275-279.
    • (2010) Antivir. Ther. , vol.15 , pp. 275-279
    • Lee, L.S.1    Soon, G.H.2    Shen, P.3    Yong, E.L.4    Flexner, C.5    Pham, P.6
  • 14
    • 0035808574 scopus 로고    scopus 로고
    • Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1-infected patients
    • DOI 10.1097/00002030-200101050-00011
    • Marzolini, C., A. Telenti, L. A. Decosterd, G. Greub, J. Biollaz, and T. Buclin. 2001. Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1-infected patients. AIDS 15:71-75. (Pubitemid 32055781)
    • (2001) AIDS , vol.15 , Issue.1 , pp. 71-75
    • Marzolini, C.1    Telenti, A.2    Decosterd, L.A.3    Greub, G.4    Biollaz, J.5    Buclin, T.6
  • 15
    • 64649102226 scopus 로고    scopus 로고
    • Darunavir: A review of its use in the management of HIV infection in adults
    • McKeage, K., C. M. Perry, and S. J. Keam. 2009. Darunavir: a review of its use in the management of HIV infection in adults. Drugs 69:477-503.
    • (2009) Drugs , vol.69 , pp. 477-503
    • McKeage, K.1    Perry, C.M.2    Keam, S.J.3
  • 17
    • 55849125465 scopus 로고    scopus 로고
    • Darunavir inhibitory quotient predicts the 48-week virological response to darunavir-based salvage therapy in human immunodeficiency virus-infected protease inhibitor-experienced patients
    • Molto, J., J. R. Santos, N. Perez-Alvarez, S. Cedeno, C. Miranda, S. Khoo, L. Else, J. M. Llibre, M. Valle, and B. Clotet. 2008. Darunavir inhibitory quotient predicts the 48-week virological response to darunavir-based salvage therapy in human immunodeficiency virus-infected protease inhibitor-experienced patients. Antimicrob. Agents Chemother. 52:3928-3932.
    • (2008) Antimicrob. Agents Chemother. , vol.52 , pp. 3928-3932
    • Molto, J.1    Santos, J.R.2    Perez-Alvarez, N.3    Cedeno, S.4    Miranda, C.5    Khoo, S.6    Else, L.7    Llibre, J.M.8    Valle, M.9    Clotet, B.10
  • 20
    • 34547628485 scopus 로고    scopus 로고
    • Fast and simultaneous determination of darunavir and eleven other antiretroviral drugs for therapeutic drug monitoring: Method development and validation for the determination of all currently approved HIV protease inhibitors and non-nucleoside reverse transcriptase inhibitors in human plasma by liquid chromatography coupled with electrospray ionization tandem mass spectrometry
    • ter Heine, R., C. G. Alderden-Los, H. Rosing, M. J. Hillebrand, E. C. van Gorp, A. D. Huitema, and J. H. Beijnen. 2007. Fast and simultaneous determination of darunavir and eleven other antiretroviral drugs for therapeutic drug monitoring: method development and validation for the determination of all currently approved HIV protease inhibitors and non-nucleoside reverse transcriptase inhibitors in human plasma by liquid chromatography coupled with electrospray ionization tandem mass spectrometry. Rapid Commun. Mass Spectrom. 21:2505-2514.
    • (2007) Rapid Commun. Mass Spectrom. , vol.21 , pp. 2505-2514
    • Ter Heine, R.1    Alderden-Los, C.G.2    Rosing, H.3    Hillebrand, M.J.4    Van Gorp, E.C.5    Huitema, A.D.6    Beijnen, J.H.7
  • 21
    • 67049173094 scopus 로고    scopus 로고
    • Model-based approach to characterize efavirenz autoinduction and concurrent enzyme induction with carbamazepine
    • Zhu, M., S. Kaul, P. Nandy, D. M. Grasela, and M. Pfister. 2009. Model-based approach to characterize efavirenz autoinduction and concurrent enzyme induction with carbamazepine. Antimicrob. Agents Chemother. 53:2346-2353.
    • (2009) Antimicrob. Agents Chemother. , vol.53 , pp. 2346-2353
    • Zhu, M.1    Kaul, S.2    Nandy, P.3    Grasela, D.M.4    Pfister, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.