메뉴 건너뛰기




Volumn 236, Issue 1, 2010, Pages 68-82

The power and the promise of restimulation-induced cell death in human immune diseases

Author keywords

Apoptosis; Autoimmunity; Signal transduction; T cells; T cell receptors

Indexed keywords

BIM PROTEIN; FAS ANTIGEN; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA;

EID: 77953740033     PISSN: 01052896     EISSN: 1600065X     Source Type: Journal    
DOI: 10.1111/j.1600-065X.2010.00917.x     Document Type: Review
Times cited : (83)

References (116)
  • 1
    • 0031573612 scopus 로고    scopus 로고
    • Effects of CD28 costimulation on long-term proliferation of CD4+ T cells in the absence of exogenous feeder cells
    • Levine BL, et al. Effects of CD28 costimulation on long-term proliferation of CD4+ T cells in the absence of exogenous feeder cells. J Immunol 1997 159 : 5921 5930.
    • (1997) J Immunol , vol.159 , pp. 5921-5930
    • Levine, B.L.1
  • 2
    • 0033007321 scopus 로고    scopus 로고
    • Mature T lymphocyte apoptosis - Immune regulation in a dynamic and unpredictable antigenic environment
    • Lenardo M, et al. Mature T lymphocyte apoptosis - immune regulation in a dynamic and unpredictable antigenic environment. Annu Rev Immunol 1999 17 : 221 253.
    • (1999) Annu Rev Immunol , vol.17 , pp. 221-253
    • Lenardo, M.1
  • 3
    • 74549162832 scopus 로고    scopus 로고
    • Prolonged interleukin-2Ralpha expression on virus-specific CD8(+) T cells favors terminal-effector differentiation in vivo
    • Kalia V, Sarkar S, Subramaniam S, Haining WN, Smith KA, Ahmed R. Prolonged interleukin-2Ralpha expression on virus-specific CD8(+) T cells favors terminal-effector differentiation in vivo. Immunity 2010 32 : 91 103.
    • (2010) Immunity , vol.32 , pp. 91-103
    • Kalia, V.1    Sarkar, S.2    Subramaniam, S.3    Haining, W.N.4    Smith, K.A.5    Ahmed, R.6
  • 4
    • 0023120729 scopus 로고
    • Cell growth cycle block of T cell hybridomas upon activation with antigen
    • Ashwell JD, Cunningham RE, Noguchi PD, Hernandez D. Cell growth cycle block of T cell hybridomas upon activation with antigen. J Exp Med 1987 165 : 173 194.
    • (1987) J Exp Med , vol.165 , pp. 173-194
    • Ashwell, J.D.1    Cunningham, R.E.2    Noguchi, P.D.3    Hernandez, D.4
  • 5
    • 0023197765 scopus 로고
    • T-cell tumor elimination as a result of T-cell receptor-mediated activation
    • Ashwell JD, Longo DL, Bridges SH. T-cell tumor elimination as a result of T-cell receptor-mediated activation. Science 1987 237 : 61 64.
    • (1987) Science , vol.237 , pp. 61-64
    • Ashwell, J.D.1    Longo, D.L.2    Bridges, S.H.3
  • 6
    • 0026017971 scopus 로고
    • Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis
    • Lenardo MJ. Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis. Nature 1991 353 : 858 861.
    • (1991) Nature , vol.353 , pp. 858-861
    • Lenardo, M.J.1
  • 7
  • 8
    • 33645784245 scopus 로고    scopus 로고
    • Genetic disorders of programmed cell death in the immune system
    • Bidere N, Su HC, Lenardo MJ. Genetic disorders of programmed cell death in the immune system. Annu Rev Immunol 2006 24 : 321 352.
    • (2006) Annu Rev Immunol , vol.24 , pp. 321-352
    • Bidere, N.1    Su, H.C.2    Lenardo, M.J.3
  • 9
    • 67649884532 scopus 로고    scopus 로고
    • CD95, BIM and T cell homeostasis
    • Bouillet P, O'Reilly LA. CD95, BIM and T cell homeostasis. Nat Rev Immunol 2009 9 : 514 519.
    • (2009) Nat Rev Immunol , vol.9 , pp. 514-519
    • Bouillet, P.1    O'Reilly, L.A.2
  • 10
    • 60149085396 scopus 로고    scopus 로고
    • The many roles of FAS receptor signaling in the immune system
    • Strasser A, Jost PJ, Nagata S. The many roles of FAS receptor signaling in the immune system. Immunity 2009 30 : 180 192.
    • (2009) Immunity , vol.30 , pp. 180-192
    • Strasser, A.1    Jost, P.J.2    Nagata, S.3
  • 11
    • 0027182225 scopus 로고
    • Propriocidal apoptosis of mature T lymphocytes occurs at S phase of the cell cycle
    • Boehme SA, Lenardo MJ. Propriocidal apoptosis of mature T lymphocytes occurs at S phase of the cell cycle. Eur J Immunol 1993 23 : 1552 1560.
    • (1993) Eur J Immunol , vol.23 , pp. 1552-1560
    • Boehme, S.A.1    Lenardo, M.J.2
  • 12
    • 0024368696 scopus 로고
    • Cyclosporin A inhibits activation-induced cell death in T-cell hybridomas and thymocytes
    • Shi YF, Sahai BM, Green DR. Cyclosporin A inhibits activation-induced cell death in T-cell hybridomas and thymocytes. Nature 1989 339 : 625 626.
    • (1989) Nature , vol.339 , pp. 625-626
    • Shi, Y.F.1    Sahai, B.M.2    Green, D.R.3
  • 13
    • 0031975910 scopus 로고    scopus 로고
    • T cell growth cytokines cause the superinduction of molecules mediating antigen-induced T lymphocyte death
    • Zheng L, Trageser CL, Willerford DM, Lenardo MJ. T cell growth cytokines cause the superinduction of molecules mediating antigen-induced T lymphocyte death. J Immunol 1998 160 : 763 769.
    • (1998) J Immunol , vol.160 , pp. 763-769
    • Zheng, L.1    Trageser, C.L.2    Willerford, D.M.3    Lenardo, M.J.4
  • 14
    • 0029118133 scopus 로고
    • Normal clonal expansion but impaired Fas-mediated cell death and anergy induction in interleukin-2-deficient mice
    • Kneitz B, Herrmann T, Yonehara S, Schimpl A. Normal clonal expansion but impaired Fas-mediated cell death and anergy induction in interleukin-2-deficient mice. Eur J Immunol 1995 25 : 2572 2577.
    • (1995) Eur J Immunol , vol.25 , pp. 2572-2577
    • Kneitz, B.1    Herrmann, T.2    Yonehara, S.3    Schimpl, A.4
  • 15
    • 0029028363 scopus 로고
    • Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta
    • Suzuki H, et al. Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor beta. Science 1995 268 : 1472 1476.
    • (1995) Science , vol.268 , pp. 1472-1476
    • Suzuki, H.1
  • 16
    • 0028784289 scopus 로고
    • Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment
    • Willerford DM, Chen J, Ferry JA, Davidson L, Ma A, Alt FW. Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment. Immunity 1995 3 : 521 530.
    • (1995) Immunity , vol.3 , pp. 521-530
    • Willerford, D.M.1    Chen, J.2    Ferry, J.A.3    Davidson, L.4    Ma, A.5    Alt, F.W.6
  • 17
    • 70349678683 scopus 로고    scopus 로고
    • Restimulation-induced apoptosis of T cells is impaired in patients with X-linked lymphoproliferative disease caused by SAP deficiency
    • Snow AL, et al. Restimulation-induced apoptosis of T cells is impaired in patients with X-linked lymphoproliferative disease caused by SAP deficiency. J Clin Invest 2009 119 : 2976 2989.
    • (2009) J Clin Invest , vol.119 , pp. 2976-2989
    • Snow, A.L.1
  • 18
    • 0022996750 scopus 로고
    • IL-2 addiction: Withdrawal of growth factor activates a suicide program in dependent T cells
    • Duke RC, Cohen JJ. IL-2 addiction: withdrawal of growth factor activates a suicide program in dependent T cells. Lymphokine Res 1986 5 : 289 299.
    • (1986) Lymphokine Res , vol.5 , pp. 289-299
    • Duke, R.C.1    Cohen, J.J.2
  • 19
    • 0024445085 scopus 로고
    • Phorbol esters inhibit apoptosis in IL-2-dependent T lymphocytes
    • Rodriguez-Tarduchy G, Lopez-Rivas A. Phorbol esters inhibit apoptosis in IL-2-dependent T lymphocytes. Biochem Biophys Res Commun 1989 164 : 1069 1075.
    • (1989) Biochem Biophys Res Commun , vol.164 , pp. 1069-1075
    • Rodriguez-Tarduchy, G.1    Lopez-Rivas, A.2
  • 20
    • 0030586563 scopus 로고    scopus 로고
    • Implantation of IL-2-containing osmotic pump prolongs the survival of superantigen-reactive T cells expanded in mice injected with bacterial superantigen
    • Kuroda K, et al. Implantation of IL-2-containing osmotic pump prolongs the survival of superantigen-reactive T cells expanded in mice injected with bacterial superantigen. J Immunol 1996 157 : 1422 1431.
    • (1996) J Immunol , vol.157 , pp. 1422-1431
    • Kuroda, K.1
  • 21
    • 36248976097 scopus 로고    scopus 로고
    • CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells
    • Pandiyan P, Zheng L, Ishihara S, Reed J, Lenardo MJ. CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells. Nat Immunol 2007 8 : 1353 1362.
    • (2007) Nat Immunol , vol.8 , pp. 1353-1362
    • Pandiyan, P.1    Zheng, L.2    Ishihara, S.3    Reed, J.4    Lenardo, M.J.5
  • 22
    • 3943071150 scopus 로고    scopus 로고
    • Cytochrome C-mediated apoptosis
    • Jiang X, Wang X. Cytochrome C-mediated apoptosis. Annu Rev Biochem 2004 73 : 87 106.
    • (2004) Annu Rev Biochem , vol.73 , pp. 87-106
    • Jiang, X.1    Wang, X.2
  • 24
    • 0042834325 scopus 로고    scopus 로고
    • An IL-2-dependent switch between CD95 signaling pathways sensitizes primary human T cells toward CD95-mediated activation-induced cell death
    • Schmitz I, Krueger A, Baumann S, Schulze-Bergkamen H, Krammer PH, Kirchhoff S. An IL-2-dependent switch between CD95 signaling pathways sensitizes primary human T cells toward CD95-mediated activation-induced cell death. J Immunol 2003 171 : 2930 2936.
    • (2003) J Immunol , vol.171 , pp. 2930-2936
    • Schmitz, I.1    Krueger, A.2    Baumann, S.3    Schulze-Bergkamen, H.4    Krammer, P.H.5    Kirchhoff, S.6
  • 25
    • 68549089038 scopus 로고    scopus 로고
    • The role of BH3-only protein Bim extends beyond inhibiting Bcl-2-like prosurvival proteins
    • Merino D, et al. The role of BH3-only protein Bim extends beyond inhibiting Bcl-2-like prosurvival proteins. J Cell Biol 2009 186 : 355 362.
    • (2009) J Cell Biol , vol.186 , pp. 355-362
    • Merino, D.1
  • 26
    • 34547461299 scopus 로고    scopus 로고
    • NRAS mutation causes a human autoimmune lymphoproliferative syndrome
    • Oliveira JB, et al. NRAS mutation causes a human autoimmune lymphoproliferative syndrome. Proc Natl Acad Sci USA 2007 104 : 8953 8958.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 8953-8958
    • Oliveira, J.B.1
  • 27
    • 0015172562 scopus 로고
    • Infectious immunological tolerance
    • Gershon RK, Kondo K. Infectious immunological tolerance. Immunology 1971 21 : 903 914.
    • (1971) Immunology , vol.21 , pp. 903-914
    • Gershon, R.K.1    Kondo, K.2
  • 28
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 1995 155 : 1151 1164.
    • (1995) J Immunol , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 29
    • 0031821875 scopus 로고    scopus 로고
    • CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
    • Thornton AM, Shevach EM. CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J Exp Med 1998 188 : 287 296.
    • (1998) J Exp Med , vol.188 , pp. 287-296
    • Thornton, A.M.1    Shevach, E.M.2
  • 31
    • 0014667395 scopus 로고
    • Thymus and reproduction: Sex-linked dysgenesia of the gonad after neonatal thymectomy in mice
    • Nishizuka Y, Sakakura T. Thymus and reproduction: sex-linked dysgenesia of the gonad after neonatal thymectomy in mice. Science 1969 166 : 753 755.
    • (1969) Science , vol.166 , pp. 753-755
    • Nishizuka, Y.1    Sakakura, T.2
  • 32
    • 0020451946 scopus 로고
    • Study on cellular events in post-thymectomy autoimmune oophoritis in mice. II. Requirements of Lyt-1 cells in normal female mice for the prevention of oophoritis
    • DOI 10.1084/jem.156.6.1577
    • Sakaguchi S, Takahashi T, Nishizuka Y. Study on cellular events in post-thymectomy autoimmune oophoritis in mice. II. Requirement of Lyt-1 cells in normal female mice for the prevention of oophoritis. J Exp Med 1982 156 : 1577 1586. (Pubitemid 13167406)
    • (1982) Journal of Experimental Medicine , vol.156 , Issue.6 , pp. 1577-1586
    • Sakaguchi, S.1    Takahashi, T.2    Nishizuka, Y.3
  • 33
    • 0020432846 scopus 로고
    • Study on cellular events in postthymectomy autoimmune oophoritis in mice. I. Requirement of Lyt-1 effector cells for oocytes damage after adoptive transfer
    • Sakaguchi S, Takahashi T, Nishizuka Y. Study on cellular events in postthymectomy autoimmune oophoritis in mice. I. Requirement of Lyt-1 effector cells for oocytes damage after adoptive transfer. J Exp Med 1982 156 : 1565 1576.
    • (1982) J Exp Med , vol.156 , pp. 1565-1576
    • Sakaguchi, S.1    Takahashi, T.2    Nishizuka, Y.3
  • 34
    • 35348876040 scopus 로고    scopus 로고
    • IPEX, FOXP3 and regulatory T-cells: A model for autoimmunity
    • Ochs HD, Gambineri E, Torgerson TR. IPEX, FOXP3 and regulatory T-cells: a model for autoimmunity. Immunol Res 2007 38 : 112 121.
    • (2007) Immunol Res , vol.38 , pp. 112-121
    • Ochs, H.D.1    Gambineri, E.2    Torgerson, T.R.3
  • 35
    • 0035163909 scopus 로고    scopus 로고
    • X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
    • Wildin RS, et al. X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. Nat Genet 2001 27 : 18 20.
    • (2001) Nat Genet , vol.27 , pp. 18-20
    • Wildin, R.S.1
  • 36
    • 13544271161 scopus 로고    scopus 로고
    • Cutting edge: Contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism
    • Gondek DC, Lu LF, Quezada SA, Sakaguchi S, Noelle RJ. Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism. J Immunol 2005 174 : 1783 1786.
    • (2005) J Immunol , vol.174 , pp. 1783-1786
    • Gondek, D.C.1    Lu, L.F.2    Quezada, S.A.3    Sakaguchi, S.4    Noelle, R.J.5
  • 37
    • 0034679560 scopus 로고    scopus 로고
    • Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
    • Takahashi T, et al. Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J Exp Med 2000 192 : 303 310.
    • (2000) J Exp Med , vol.192 , pp. 303-310
    • Takahashi, T.1
  • 38
    • 0031647622 scopus 로고    scopus 로고
    • Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state
    • Takahashi T, et al. Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int Immunol 1998 10 : 1969 1980.
    • (1998) Int Immunol , vol.10 , pp. 1969-1980
    • Takahashi, T.1
  • 39
    • 1642390941 scopus 로고    scopus 로고
    • Activation requirements for the induction of CD4+CD25+ T cell suppressor function
    • Thornton AM, Piccirillo CA, Shevach EM. Activation requirements for the induction of CD4+CD25+ T cell suppressor function. Eur J Immunol 2004 34 : 366 376.
    • (2004) Eur J Immunol , vol.34 , pp. 366-376
    • Thornton, A.M.1    Piccirillo, C.A.2    Shevach, E.M.3
  • 40
    • 14944386649 scopus 로고    scopus 로고
    • CD25+ CD4+ T cells compete with naive CD4+ T cells for IL-2 and exploit it for the induction of IL-10 production
    • Barthlott T, et al. CD25+ CD4+ T cells compete with naive CD4+ T cells for IL-2 and exploit it for the induction of IL-10 production. Int Immunol 2005 17 : 279 288.
    • (2005) Int Immunol , vol.17 , pp. 279-288
    • Barthlott, T.1
  • 41
    • 18844371714 scopus 로고    scopus 로고
    • Regulation of CD4+CD25+ regulatory T cell activity: It takes (IL-)two to tango
    • Scheffold A, Huhn J, Hofer T. Regulation of CD4+CD25+ regulatory T cell activity: it takes (IL-)two to tango. Eur J Immunol 2005 35 : 1336 1341.
    • (2005) Eur J Immunol , vol.35 , pp. 1336-1341
    • Scheffold, A.1    Huhn, J.2    Hofer, T.3
  • 42
    • 0036695190 scopus 로고    scopus 로고
    • IL-2 and autoimmune disease
    • Schimpl A, et al. IL-2 and autoimmune disease. Cytokine Growth Factor Rev 2002 13 : 369 378.
    • (2002) Cytokine Growth Factor Rev , vol.13 , pp. 369-378
    • Schimpl, A.1
  • 43
    • 41149124867 scopus 로고    scopus 로고
    • The control of CD4+CD25+Foxp3+ regulatory T cell survival
    • Pandiyan P, Lenardo MJ. The control of CD4+CD25+Foxp3+ regulatory T cell survival. Biol Direct 2008 3 : 6.
    • (2008) Biol Direct , vol.3 , pp. 6
    • Pandiyan, P.1    Lenardo, M.J.2
  • 44
    • 0033985780 scopus 로고    scopus 로고
    • Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific
    • Thornton AM, Shevach EM. Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific. J Immunol 2000 164 : 183 190.
    • (2000) J Immunol , vol.164 , pp. 183-190
    • Thornton, A.M.1    Shevach, E.M.2
  • 45
    • 0035675798 scopus 로고    scopus 로고
    • IPEX is a unique X-linked syndrome characterized by immune dysfunction, polyendocrinopathy, enteropathy, and a variety of autoimmune phenomena
    • Bennett CL, Ochs HD. IPEX is a unique X-linked syndrome characterized by immune dysfunction, polyendocrinopathy, enteropathy, and a variety of autoimmune phenomena. Curr Opin Pediatr 2001 13 : 533 538.
    • (2001) Curr Opin Pediatr , vol.13 , pp. 533-538
    • Bennett, C.L.1    Ochs, H.D.2
  • 46
    • 0033607506 scopus 로고    scopus 로고
    • Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
    • Bouillet P, et al. Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science 1999 286 : 1735 1738.
    • (1999) Science , vol.286 , pp. 1735-1738
    • Bouillet, P.1
  • 47
    • 0036069819 scopus 로고    scopus 로고
    • Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim
    • Hildeman DA, et al. Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim. Immunity 2002 16 : 759 767.
    • (2002) Immunity , vol.16 , pp. 759-767
    • Hildeman, D.A.1
  • 48
    • 34248340997 scopus 로고    scopus 로고
    • Deficiency of Bim in dendritic cells contributes to overactivation of lymphocytes and autoimmunity
    • Chen M, Huang L, Wang J. Deficiency of Bim in dendritic cells contributes to overactivation of lymphocytes and autoimmunity. Blood 2007 109 : 4360 4367.
    • (2007) Blood , vol.109 , pp. 4360-4367
    • Chen, M.1    Huang, L.2    Wang, J.3
  • 49
    • 0037037543 scopus 로고    scopus 로고
    • Peripheral deletion of autoreactive CD8 T cells by cross presentation of self-antigen occurs by a Bcl-2-inhibitable pathway mediated by Bim
    • Davey GM, et al. Peripheral deletion of autoreactive CD8 T cells by cross presentation of self-antigen occurs by a Bcl-2-inhibitable pathway mediated by Bim. J Exp Med 2002 196 : 947 955.
    • (2002) J Exp Med , vol.196 , pp. 947-955
    • Davey, G.M.1
  • 50
    • 0141959215 scopus 로고    scopus 로고
    • Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells
    • Enders A, Bouillet P, Puthalakath H, Xu Y, Tarlinton DM, Strasser A. Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells. J Exp Med 2003 198 : 1119 1126.
    • (2003) J Exp Med , vol.198 , pp. 1119-1126
    • Enders, A.1    Bouillet, P.2    Puthalakath, H.3    Xu, Y.4    Tarlinton, D.M.5    Strasser, A.6
  • 51
    • 33748641378 scopus 로고    scopus 로고
    • Role of Bim in regulating CD8+ T-cell responses during chronic viral infection
    • Grayson JM, Weant AE, Holbrook BC, Hildeman D. Role of Bim in regulating CD8+ T-cell responses during chronic viral infection. J Virol 2006 80 : 8627 8638.
    • (2006) J Virol , vol.80 , pp. 8627-8638
    • Grayson, J.M.1    Weant, A.E.2    Holbrook, B.C.3    Hildeman, D.4
  • 52
    • 0344198588 scopus 로고    scopus 로고
    • Shutdown of an acute T cell immune response to viral infection is mediated by the proapoptotic Bcl-2 homology 3-only protein Bim
    • Pellegrini M, Belz G, Bouillet P, Strasser A. Shutdown of an acute T cell immune response to viral infection is mediated by the proapoptotic Bcl-2 homology 3-only protein Bim. Proc Natl Acad Sci USA 2003 100 : 14175 14180.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 14175-14180
    • Pellegrini, M.1    Belz, G.2    Bouillet, P.3    Strasser, A.4
  • 53
    • 33845913794 scopus 로고    scopus 로고
    • Puma cooperates with Bim, the rate-limiting BH3-only protein in cell death during lymphocyte development, in apoptosis induction
    • Erlacher M, et al. Puma cooperates with Bim, the rate-limiting BH3-only protein in cell death during lymphocyte development, in apoptosis induction. J Exp Med 2006 203 : 2939 2951.
    • (2006) J Exp Med , vol.203 , pp. 2939-2951
    • Erlacher, M.1
  • 54
    • 42949179577 scopus 로고    scopus 로고
    • BH3-only protein Puma contributes to death of antigen-specific T cells during shutdown of an immune response to acute viral infection
    • Fischer SF, Belz GT, Strasser A. BH3-only protein Puma contributes to death of antigen-specific T cells during shutdown of an immune response to acute viral infection. Proc Natl Acad Sci USA 2008 105 : 3035 3040.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 3035-3040
    • Fischer, S.F.1    Belz, G.T.2    Strasser, A.3
  • 55
    • 0038482050 scopus 로고    scopus 로고
    • Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim
    • Ley R, Balmanno K, Hadfield K, Weston C, Cook SJ. Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim. J Biol Chem 2003 278 : 18811 18816.
    • (2003) J Biol Chem , vol.278 , pp. 18811-18816
    • Ley, R.1    Balmanno, K.2    Hadfield, K.3    Weston, C.4    Cook, S.J.5
  • 56
    • 33845965024 scopus 로고    scopus 로고
    • Cytokines direct the regulation of Bim mRNA stability by heat-shock cognate protein 70
    • Matsui H, Asou H, Inaba T. Cytokines direct the regulation of Bim mRNA stability by heat-shock cognate protein 70. Mol Cell 2007 25 : 99 112.
    • (2007) Mol Cell , vol.25 , pp. 99-112
    • Matsui, H.1    Asou, H.2    Inaba, T.3
  • 58
    • 0028223847 scopus 로고
    • Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand
    • Takahashi T, et al. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 1994 76 : 969 976.
    • (1994) Cell , vol.76 , pp. 969-976
    • Takahashi, T.1
  • 59
    • 0026568919 scopus 로고
    • Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
    • Watanabe-Fukunaga R, Brannan CI, Copeland NG, Jenkins NA, Nagata S. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 1992 356 : 314 317.
    • (1992) Nature , vol.356 , pp. 314-317
    • Watanabe-Fukunaga, R.1    Brannan, C.I.2    Copeland, N.G.3    Jenkins, N.A.4    Nagata, S.5
  • 60
    • 0028206753 scopus 로고
    • A specific intercellular pathway of apoptotic cell death is defective in the mature peripheral T cells of autoimmune lpr and gld mice
    • Gillette-Ferguson I, Sidman CL. A specific intercellular pathway of apoptotic cell death is defective in the mature peripheral T cells of autoimmune lpr and gld mice. Eur J Immunol 1994 24 : 1181 1185.
    • (1994) Eur J Immunol , vol.24 , pp. 1181-1185
    • Gillette-Ferguson, I.1    Sidman, C.L.2
  • 61
    • 0027314703 scopus 로고
    • Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide
    • Russell JH, Rush B, Weaver C, Wang R. Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide. Proc Natl Acad Sci USA 1993 90 : 4409 4413.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 4409-4413
    • Russell, J.H.1    Rush, B.2    Weaver, C.3    Wang, R.4
  • 62
    • 0028909197 scopus 로고
    • Fas ligand mediates activation-induced cell death in human T lymphocytes
    • Alderson MR, et al. Fas ligand mediates activation-induced cell death in human T lymphocytes. J Exp Med 1995 181 : 71 77.
    • (1995) J Exp Med , vol.181 , pp. 71-77
    • Alderson, M.R.1
  • 63
    • 0028983657 scopus 로고
    • Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas
    • Brunner T, et al. Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature 1995 373 : 441 444.
    • (1995) Nature , vol.373 , pp. 441-444
    • Brunner, T.1
  • 65
    • 0028893078 scopus 로고
    • Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation
    • Ju ST, et al. Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation. Nature 1995 373 : 444 448.
    • (1995) Nature , vol.373 , pp. 444-448
    • Ju, S.T.1
  • 66
    • 0031572509 scopus 로고    scopus 로고
    • Maintenance of clonotype specificity in CD95/Apo-1/Fas-mediated apoptosis of mature T lymphocytes
    • Hornung F, Zheng L, Lenardo MJ. Maintenance of clonotype specificity in CD95/Apo-1/Fas-mediated apoptosis of mature T lymphocytes. J Immunol 1997 159 : 3816 3822.
    • (1997) J Immunol , vol.159 , pp. 3816-3822
    • Hornung, F.1    Zheng, L.2    Lenardo, M.J.3
  • 67
    • 0026758658 scopus 로고
    • A novel lymphoproliferative/autoimmune syndrome resembling murine lpr/gld disease
    • Sneller MC, et al. A novel lymphoproliferative/autoimmune syndrome resembling murine lpr/gld disease. J Clin Invest 1992 90 : 334 341.
    • (1992) J Clin Invest , vol.90 , pp. 334-341
    • Sneller, M.C.1
  • 68
    • 0029025441 scopus 로고
    • Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome
    • Fisher GH, et al. Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome. Cell 1995 81 : 935 946.
    • (1995) Cell , vol.81 , pp. 935-946
    • Fisher, G.H.1
  • 69
    • 0029006893 scopus 로고
    • Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity
    • Rieux-Laucat F, et al. Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity. Science 1995 268 : 1347 1349.
    • (1995) Science , vol.268 , pp. 1347-1349
    • Rieux-Laucat, F.1
  • 70
    • 4644240701 scopus 로고    scopus 로고
    • Autoimmune lymphoproliferative syndrome with somatic Fas mutations
    • Holzelova E, et al. Autoimmune lymphoproliferative syndrome with somatic Fas mutations. N Engl J Med 2004 351 : 1409 1418.
    • (2004) N Engl J Med , vol.351 , pp. 1409-1418
    • Holzelova, E.1
  • 71
    • 0033538475 scopus 로고    scopus 로고
    • Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II
    • Wang J, et al. Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II. Cell 1999 98 : 47 58.
    • (1999) Cell , vol.98 , pp. 47-58
    • Wang, J.1
  • 72
    • 0029737324 scopus 로고    scopus 로고
    • Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease
    • Wu J, Wilson J, He J, Xiang L, Schur PH, Mountz JD. Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease. J Clin Invest 1996 98 : 1107 1113.
    • (1996) J Clin Invest , vol.98 , pp. 1107-1113
    • Wu, J.1    Wilson, J.2    He, J.3    Xiang, L.4    Schur, P.H.5    Mountz, J.D.6
  • 73
    • 70349229827 scopus 로고    scopus 로고
    • Abundant c-Fas-associated death domain-like interleukin-1-converting enzyme inhibitory protein expression determines resistance of T helper 17 cells to activation-induced cell death
    • Yu Y, et al. Abundant c-Fas-associated death domain-like interleukin-1-converting enzyme inhibitory protein expression determines resistance of T helper 17 cells to activation-induced cell death. Blood 2009 114 : 1026 1028.
    • (2009) Blood , vol.114 , pp. 1026-1028
    • Yu, Y.1
  • 74
    • 47949108785 scopus 로고    scopus 로고
    • Th17 cells undergo Fas-mediated activation-induced cell death independent of IFN-gamma
    • Zhang Y, Xu G, Zhang L, Roberts AI, Shi Y. Th17 cells undergo Fas-mediated activation-induced cell death independent of IFN-gamma. J Immunol 2008 181 : 190 196.
    • (2008) J Immunol , vol.181 , pp. 190-196
    • Zhang, Y.1    Xu, G.2    Zhang, L.3    Roberts, A.I.4    Shi, Y.5
  • 75
    • 0029817246 scopus 로고    scopus 로고
    • T-lymphocyte downregulation after acute viral infection is not dependent on CD95 (Fas) receptor-ligand interactions
    • Lohman BL, Razvi ES, Welsh RM. T-lymphocyte downregulation after acute viral infection is not dependent on CD95 (Fas) receptor-ligand interactions. J Virol 1996 70 : 8199 8203.
    • (1996) J Virol , vol.70 , pp. 8199-8203
    • Lohman, B.L.1    Razvi, E.S.2    Welsh, R.M.3
  • 76
    • 0029796812 scopus 로고    scopus 로고
    • Homeostatic regulation of CD8+ T cells after antigen challenge in the absence of Fas (CD95)
    • Zimmermann C, Rawiel M, Blaser C, Kaufmann M, Pircher H. Homeostatic regulation of CD8+ T cells after antigen challenge in the absence of Fas (CD95). Eur J Immunol 1996 26 : 2903 2910.
    • (1996) Eur J Immunol , vol.26 , pp. 2903-2910
    • Zimmermann, C.1    Rawiel, M.2    Blaser, C.3    Kaufmann, M.4    Pircher, H.5
  • 78
    • 14544288632 scopus 로고    scopus 로고
    • CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death
    • Janssen EM, et al. CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death. Nature 2005 434 : 88 93.
    • (2005) Nature , vol.434 , pp. 88-93
    • Janssen, E.M.1
  • 79
    • 39649120372 scopus 로고    scopus 로고
    • Perforin-dependent apoptosis functionally compensates Fas deficiency in activation-induced cell death of human T lymphocytes
    • Mateo V, et al. Perforin-dependent apoptosis functionally compensates Fas deficiency in activation-induced cell death of human T lymphocytes. Blood 2007 110 : 4285 4292.
    • (2007) Blood , vol.110 , pp. 4285-4292
    • Mateo, V.1
  • 80
    • 33747144028 scopus 로고    scopus 로고
    • Granzyme B is critical for T cell receptor-induced cell death of type 2 helper T cells
    • Devadas S, et al. Granzyme B is critical for T cell receptor-induced cell death of type 2 helper T cells. Immunity 2006 25 : 237 247.
    • (2006) Immunity , vol.25 , pp. 237-247
    • Devadas, S.1
  • 81
    • 43049112084 scopus 로고    scopus 로고
    • Bim-mediated deletion of antigen-specific CD8 T cells in patients unable to control HBV infection
    • Lopes AR, et al. Bim-mediated deletion of antigen-specific CD8 T cells in patients unable to control HBV infection. J Clin Invest 2008 118 : 1835 1845.
    • (2008) J Clin Invest , vol.118 , pp. 1835-1845
    • Lopes, A.R.1
  • 82
    • 34248577055 scopus 로고    scopus 로고
    • Elimination of antigen-presenting cells and autoreactive T cells by Fas contributes to prevention of autoimmunity
    • Stranges PB, et al. Elimination of antigen-presenting cells and autoreactive T cells by Fas contributes to prevention of autoimmunity. Immunity 2007 26 : 629 641.
    • (2007) Immunity , vol.26 , pp. 629-641
    • Stranges, P.B.1
  • 83
    • 57449117459 scopus 로고    scopus 로고
    • Prevention of autoimmunity and control of recall response to exogenous antigen by Fas death receptor ligand expression on T cells
    • Mabrouk I, et al. Prevention of autoimmunity and control of recall response to exogenous antigen by Fas death receptor ligand expression on T cells. Immunity 2008 29 : 922 933.
    • (2008) Immunity , vol.29 , pp. 922-933
    • Mabrouk, I.1
  • 84
    • 53349167095 scopus 로고    scopus 로고
    • Fas receptor expression in germinal-center B cells is essential for T and B lymphocyte homeostasis
    • Hao Z, et al. Fas receptor expression in germinal-center B cells is essential for T and B lymphocyte homeostasis. Immunity 2008 29 : 615 627.
    • (2008) Immunity , vol.29 , pp. 615-627
    • Hao, Z.1
  • 85
    • 0035412359 scopus 로고    scopus 로고
    • The development of lymphomas in families with autoimmune lymphoproliferative syndrome with germline Fas mutations and defective lymphocyte apoptosis
    • Straus SE, et al. The development of lymphomas in families with autoimmune lymphoproliferative syndrome with germline Fas mutations and defective lymphocyte apoptosis. Blood 2001 98 : 194 200.
    • (2001) Blood , vol.98 , pp. 194-200
    • Straus, S.E.1
  • 86
    • 37049019709 scopus 로고    scopus 로고
    • Caspase-cleaved HPK1 induces CD95L-independent activation-induced cell death in T and B lymphocytes
    • Brenner D, et al. Caspase-cleaved HPK1 induces CD95L-independent activation-induced cell death in T and B lymphocytes. Blood 2007 110 : 3968 3977.
    • (2007) Blood , vol.110 , pp. 3968-3977
    • Brenner, D.1
  • 87
    • 1542327683 scopus 로고    scopus 로고
    • Regulation of expression of Bcl-2 protein family member Bim by T cell receptor triggering
    • Sandalova E, Wei CH, Masucci MG, Levitsky V. Regulation of expression of Bcl-2 protein family member Bim by T cell receptor triggering. Proc Natl Acad Sci USA 2004 101 : 3011 3016.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 3011-3016
    • Sandalova, E.1    Wei, C.H.2    Masucci, M.G.3    Levitsky, V.4
  • 88
    • 38949119408 scopus 로고    scopus 로고
    • Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity
    • Hughes PD, Belz GT, Fortner KA, Budd RC, Strasser A, Bouillet P. Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity. Immunity 2008 28 : 197 205.
    • (2008) Immunity , vol.28 , pp. 197-205
    • Hughes, P.D.1    Belz, G.T.2    Fortner, K.A.3    Budd, R.C.4    Strasser, A.5    Bouillet, P.6
  • 89
    • 38949209522 scopus 로고    scopus 로고
    • Combined deficiency of proapoptotic regulators Bim and Fas results in the early onset of systemic autoimmunity
    • Hutcheson J, et al. Combined deficiency of proapoptotic regulators Bim and Fas results in the early onset of systemic autoimmunity. Immunity 2008 28 : 206 217.
    • (2008) Immunity , vol.28 , pp. 206-217
    • Hutcheson, J.1
  • 90
    • 38949210228 scopus 로고    scopus 로고
    • Apoptosis regulators Bim and Fas function concurrently to control autoimmunity and CD8(+) T cell contraction
    • Weant AE, Michalek RD, Khan IU, Holbrook BC, Willingham MC, Grayson JM. Apoptosis regulators Bim and Fas function concurrently to control autoimmunity and CD8(+) T cell contraction. Immunity 2008 28 : 218 230.
    • (2008) Immunity , vol.28 , pp. 218-230
    • Weant, A.E.1    Michalek, R.D.2    Khan, I.U.3    Holbrook, B.C.4    Willingham, M.C.5    Grayson, J.M.6
  • 92
    • 0029609086 scopus 로고
    • Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis
    • Strasser A, Harris AW, Huang DC, Krammer PH, Cory S. Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis. EMBO J 1995 14 : 6136 6147.
    • (1995) EMBO J , vol.14 , pp. 6136-6147
    • Strasser, A.1    Harris, A.W.2    Huang, D.C.3    Krammer, P.H.4    Cory, S.5
  • 93
    • 0029891157 scopus 로고    scopus 로고
    • Qualitative and quantitative contributions of the T cell receptor zeta chain to mature T cell apoptosis
    • Combadiere B, Freedman M, Chen L, Shores EW, Love P, Lenardo MJ. Qualitative and quantitative contributions of the T cell receptor zeta chain to mature T cell apoptosis. J Exp Med 1996 183 : 2109 2117.
    • (1996) J Exp Med , vol.183 , pp. 2109-2117
    • Combadiere, B.1    Freedman, M.2    Chen, L.3    Shores, E.W.4    Love, P.5    Lenardo, M.J.6
  • 94
    • 0031786581 scopus 로고    scopus 로고
    • Activation-induced apoptosis of mature T cells is dependent upon the level of surface TCR but not on the presence of the CD3 zeta ITAM
    • She J, Matsui K, Terhorst C, Ju ST. Activation-induced apoptosis of mature T cells is dependent upon the level of surface TCR but not on the presence of the CD3 zeta ITAM. Int Immunol 1998 10 : 1733 1740.
    • (1998) Int Immunol , vol.10 , pp. 1733-1740
    • She, J.1    Matsui, K.2    Terhorst, C.3    Ju, S.T.4
  • 95
    • 0029148745 scopus 로고
    • Analysis of the CD4 coreceptor and activation-induced costimulatory molecules in antigen-mediated mature T lymphocyte death
    • Boehme SA, Zheng L, Lenardo MJ. Analysis of the CD4 coreceptor and activation-induced costimulatory molecules in antigen-mediated mature T lymphocyte death. J Immunol 1995 155 : 1703 1712.
    • (1995) J Immunol , vol.155 , pp. 1703-1712
    • Boehme, S.A.1    Zheng, L.2    Lenardo, M.J.3
  • 96
    • 0016772968 scopus 로고
    • X-linked recessive progressive combined variable immunodeficiency (Duncan's disease)
    • Purtilo DT, Cassel CK, Yang JP, Harper R. X-linked recessive progressive combined variable immunodeficiency (Duncan's disease). Lancet 1975 1 : 935 940.
    • (1975) Lancet , vol.1 , pp. 935-940
    • Purtilo, D.T.1    Cassel, C.K.2    Yang, J.P.3    Harper, R.4
  • 97
    • 0029161779 scopus 로고
    • X-linked lymphoproliferative disease: Twenty-five years after the discovery
    • Seemayer TA, et al. X-linked lymphoproliferative disease: twenty-five years after the discovery. Pediatr Res 1995 38 : 471 478.
    • (1995) Pediatr Res , vol.38 , pp. 471-478
    • Seemayer, T.A.1
  • 98
    • 34247892632 scopus 로고    scopus 로고
    • Regulation of cellular and humoral immune responses by the SLAM and SAP families of molecules
    • Ma CS, Nichols KE, Tangye SG. Regulation of cellular and humoral immune responses by the SLAM and SAP families of molecules. Annu Rev Immunol 2007 25 : 337 379.
    • (2007) Annu Rev Immunol , vol.25 , pp. 337-379
    • Ma, C.S.1    Nichols, K.E.2    Tangye, S.G.3
  • 99
    • 0032190081 scopus 로고    scopus 로고
    • The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM
    • Sayos J, et al. The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM. Nature 1998 395 : 462 469.
    • (1998) Nature , vol.395 , pp. 462-469
    • Sayos, J.1
  • 101
    • 0035817326 scopus 로고    scopus 로고
    • NTB-A [correction of GNTB-A], a novel SH2D1A-associated surface molecule contributing to the inability of natural killer cells to kill Epstein-Barr virus-infected B cells in X-linked lymphoproliferative disease
    • Bottino C, et al. NTB-A [correction of GNTB-A], a novel SH2D1A-associated surface molecule contributing to the inability of natural killer cells to kill Epstein-Barr virus-infected B cells in X-linked lymphoproliferative disease. J Exp Med 2001 194 : 235 246.
    • (2001) J Exp Med , vol.194 , pp. 235-246
    • Bottino, C.1
  • 102
    • 0037338890 scopus 로고    scopus 로고
    • TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways
    • Stefanova I, Hemmer B, Vergelli M, Martin R, Biddison WE, Germain RN. TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways. Nat Immunol 2003 4 : 248 254.
    • (2003) Nat Immunol , vol.4 , pp. 248-254
    • Stefanova, I.1    Hemmer, B.2    Vergelli, M.3    Martin, R.4    Biddison, W.E.5    Germain, R.N.6
  • 103
    • 33745032268 scopus 로고    scopus 로고
    • SAP regulates T cell-mediated help for humoral immunity by a mechanism distinct from cytokine regulation
    • Cannons JL, et al. SAP regulates T cell-mediated help for humoral immunity by a mechanism distinct from cytokine regulation. J Exp Med 2006 203 : 1551 1565.
    • (2006) J Exp Med , vol.203 , pp. 1551-1565
    • Cannons, J.L.1
  • 104
    • 0035496101 scopus 로고    scopus 로고
    • Epstein-Barr virus: Exploiting the immune system
    • Thorley-Lawson DA. Epstein-Barr virus: exploiting the immune system. Nat Rev Immunol 2001 1 : 75 82.
    • (2001) Nat Rev Immunol , vol.1 , pp. 75-82
    • Thorley-Lawson, D.A.1
  • 105
    • 53649107278 scopus 로고    scopus 로고
    • SAP-controlled T-B cell interactions underlie germinal centre formation
    • Qi H, Cannons JL, Klauschen F, Schwartzberg PL, Germain RN. SAP-controlled T-B cell interactions underlie germinal centre formation. Nature 2008 455 : 764 769.
    • (2008) Nature , vol.455 , pp. 764-769
    • Qi, H.1    Cannons, J.L.2    Klauschen, F.3    Schwartzberg, P.L.4    Germain, R.N.5
  • 106
    • 61849157792 scopus 로고    scopus 로고
    • X-linked lymphoproliferative disease (XLP): A model of impaired anti-viral, anti-tumor and humoral immune responses
    • Bassiri H, Janice Yeo WC, Rothman J, Koretzky GA, Nichols KE. X-linked lymphoproliferative disease (XLP): a model of impaired anti-viral, anti-tumor and humoral immune responses. Immunol Res 2008 42 : 145 159.
    • (2008) Immunol Res , vol.42 , pp. 145-159
    • Bassiri, H.1    Janice Yeo, W.C.2    Rothman, J.3    Koretzky, G.A.4    Nichols, K.E.5
  • 107
    • 33750385770 scopus 로고    scopus 로고
    • Hypogammaglobulinemia and exacerbated CD8 T-cell-mediated immunopathology in SAP-deficient mice with chronic LCMV infection mimics human XLP disease
    • Crotty S, McCausland MM, Aubert RD, Wherry EJ, Ahmed R. Hypogammaglobulinemia and exacerbated CD8 T-cell-mediated immunopathology in SAP-deficient mice with chronic LCMV infection mimics human XLP disease. Blood 2006 108 : 3085 3093.
    • (2006) Blood , vol.108 , pp. 3085-3093
    • Crotty, S.1    McCausland, M.M.2    Aubert, R.D.3    Wherry, E.J.4    Ahmed, R.5
  • 108
    • 0035912823 scopus 로고    scopus 로고
    • Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP
    • Czar MJ, et al. Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP. Proc Natl Acad Sci USA 2001 98 : 7449 7454.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 7449-7454
    • Czar, M.J.1
  • 109
    • 0141535212 scopus 로고    scopus 로고
    • Mice deficient in the X-linked lymphoproliferative disease gene sap exhibit increased susceptibility to murine gammaherpesvirus-68 and hypo-gammaglobulinemia
    • Yin L, et al. Mice deficient in the X-linked lymphoproliferative disease gene sap exhibit increased susceptibility to murine gammaherpesvirus-68 and hypo-gammaglobulinemia. J Med Virol 2003 71 : 446 455.
    • (2003) J Med Virol , vol.71 , pp. 446-455
    • Yin, L.1
  • 110
    • 34147192525 scopus 로고    scopus 로고
    • Increased proliferation of CD8+ T cells in SAP-deficient mice is associated with impaired activation-induced cell death
    • Chen G, Tai AK, Lin M, Chang F, Terhorst C, Huber BT. Increased proliferation of CD8+ T cells in SAP-deficient mice is associated with impaired activation-induced cell death. Eur J Immunol 2007 37 : 663 674.
    • (2007) Eur J Immunol , vol.37 , pp. 663-674
    • Chen, G.1    Tai, A.K.2    Lin, M.3    Chang, F.4    Terhorst, C.5    Huber, B.T.6
  • 111
    • 77950960418 scopus 로고    scopus 로고
    • Deficiency of the proapoptotic SAP function in X-linked lymphoproliferative disease aggravates Epstein-Barr virus (EBV) induced mononucleosis and promotes lymphoma development
    • Nagy N, Klein E. Deficiency of the proapoptotic SAP function in X-linked lymphoproliferative disease aggravates Epstein-Barr virus (EBV) induced mononucleosis and promotes lymphoma development. Immunol Lett 2010 130 : 13 18.
    • (2010) Immunol Lett , vol.130 , pp. 13-18
    • Nagy, N.1    Klein, E.2
  • 112
    • 67749096266 scopus 로고    scopus 로고
    • The proapoptotic function of SAP provides a clue to the clinical picture of X-linked lymphoproliferative disease
    • Nagy N, Matskova L, Kis LL, Hellman U, Klein G, Klein E. The proapoptotic function of SAP provides a clue to the clinical picture of X-linked lymphoproliferative disease. Proc Natl Acad Sci USA 2009 106 : 11966 11971.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 11966-11971
    • Nagy, N.1    Matskova, L.2    Kis, L.L.3    Hellman, U.4    Klein, G.5    Klein, E.6
  • 113
    • 0028215537 scopus 로고
    • T cell deletion in high antigen dose therapy of autoimmune encephalomyelitis
    • Critchfield JM, et al. T cell deletion in high antigen dose therapy of autoimmune encephalomyelitis. Science 1994 263 : 1139 1143.
    • (1994) Science , vol.263 , pp. 1139-1143
    • Critchfield, J.M.1
  • 114
    • 0002384347 scopus 로고
    • Induction of immunological paralysis in two zones of dosage
    • Mitchison NA. Induction of immunological paralysis in two zones of dosage. Proc R Soc Lond B Biol Sci 1964 161 : 275 292.
    • (1964) Proc R Soc Lond B Biol Sci , vol.161 , pp. 275-292
    • Mitchison, N.A.1
  • 115
    • 56149117346 scopus 로고    scopus 로고
    • Rapid deletional peripheral CD8 T cell tolerance induced by allogeneic bone marrow: Role of donor class II MHC and B cells
    • Fehr T, et al. Rapid deletional peripheral CD8 T cell tolerance induced by allogeneic bone marrow: role of donor class II MHC and B cells. J Immunol 2008 181 : 4371 4380.
    • (2008) J Immunol , vol.181 , pp. 4371-4380
    • Fehr, T.1
  • 116
    • 66549100257 scopus 로고    scopus 로고
    • The molecular signature of CD8+ T cells undergoing deletional tolerance
    • Parish IA, et al. The molecular signature of CD8+ T cells undergoing deletional tolerance. Blood 2009 113 : 4575 4585.
    • (2009) Blood , vol.113 , pp. 4575-4585
    • Parish, I.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.