Role of excitatory amino acid input in rostral ventrolateral medulla neurons in rats with obesity-induced hypertension

Acta Neurologica Belgica

Volumn 110, Issue 1, 2010, Pages 57-64

  Suhaimi, Farah Wahida ^a   Yusoff, Nurul Hasnida Mohammad ^a   Dewa, Aidiahmad ^a   Yusof, Ahmad Pauzi M D ^b  

^a SCHOOL OF PHARMACEUTICAL SCIENCES   (Malaysia)

^b Masterskill University   (Malaysia)

Author keywords

Blood pressure; Excitatory amino acid; Hypertension; Obesity; Rostral ventrolateral medulla

Indexed keywords

EXCITATORY AMINO ACID; GLUTAMIC ACID; KYNURENIC ACID; AMINO ACID RECEPTOR BLOCKING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; HYPERTENSION; INJECTION; LIPID DIET; LOW FAT DIET; MALE; MEAN ARTERIAL PRESSURE; MEDULLA OBLONGATA; NERVE CELL; NONHUMAN; OBESITY; RAT; ROSTRAL VENTROLATERAL MEDULLA; ANALYSIS OF VARIANCE; ANIMAL; BLOOD PRESSURE; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECT; EATING; INJURY; METABOLISM; METHODOLOGY; MICROINJECTION; NERVE TRACT; PATHOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ADIPOSITY; ANALYSIS OF VARIANCE; ANIMALS; BLOOD PRESSURE; BODY WEIGHT; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EATING; EXCITATORY AMINO ACID ANTAGONISTS; EXCITATORY AMINO ACIDS; HYPERTENSION; KYNURENIC ACID; MALE; MEDULLA OBLONGATA; MICROINJECTIONS; NEURAL PATHWAYS; NEURONS; OBESITY; RATS; RATS, SPRAGUE-DAWLEY;

EID: 77953726920     PISSN: 03009009     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Araujo GC, Lopes OU, Campos RR. Importance of glycinergic and glutamatergic synapses within the rostral ventrolateral medulla for blood pressure regulation in conscious rats. Hypertension. 1999;34(2):752-755.
2. Bachelard H, Gardiner SM, Bennett T. Cardiovascular responses elicited by chemical stimulation of the rostral ventrolateral medulla in conscious, unrestrained rats. Journal of Autonomic Nervous System 1990;31:185-190.
3. Badoer E. Hypothalamic paraventricular nucleus and cardiovascular regulation. Clinical and Experimental Pharmacology and Physiology. 2001;28:95-99.
4. Brooks VL, Freeman KL, Clow KA. Excitatory amino acids in rostral ventrolateral medulla support blood pressure during water deprivation in rats. Am J Physiol Heart Circ Physiol. 2004;286: H1642-H1648.
5. Boustany CM, Brown DR, Randall DC, Cassis LA. AT1-receptor antagonism reverses the blood pressure elevation associated with diet-induced obesity. Am J Physiol Regul Integr Comp Physiol. 2005;289: R181-R186.
6. Carroll JF, Zenebe WJ, Strange TB. Cardiovascular Function in a rat model of diet-induced obesity. American Heart Association, Inc. 2006;48(1):65-72.
7. Dobrian AD, Davies MJ, Prewitt RL, Lauterio TJ. Development of hypertension in a rat model of dietinduced obesity. Hypertension. 2000;35(4):1009-1015.
8. Dobrian AD, Davies MJ, Schriver SD, Lauterio TJ, Prewitt RL. Oxidative stress in a rat model of obesity-induced hypertension. Hypertension. 2001;37 [part 2]: 554-560.
9. Hall JE. The kidney, hypertension, and obesity. Hypertension 2003;41:625.
10. Horiuchi J, Killinger S, Dampney R A L. Contribution to sympathetic vasomotor tone of tonic glutamatergic inputs to neurons in the RVLM. American Journal of Physiology Regul Integr Comp Physiol. 2004;287: R1335-R1343.
11. Hu L, Zhu DN, Yu Z, Wang JQ, Sun ZJ, Yao T. Expression of angiotensin II type 1 (AT1) receptor in the rostral ventrolateral medulla in rats. Journal of Applied Physiology. 2002;92:2153-2161.
12. Ito S, Komatsu K, Tsukamoto K, Sved AF. Excitatory amino acids in the Rostral Ventrolateral Medulla support blood pressure in Spontaneously Hyper - tensive Rats. Hypertension. 2000;35:413.
13. Ito S, Komatsu K, Tsukamoto K, Sved AF. Tonic Excitatory Input to the Rostral Ventrolateral Medulla in Dahl Salt-Sensitive Rats. Hypertension. 2001;37:687.
14. Ito S, Komatsu K, Tsukamoto K, Kanmatsuse K, Sved AF. Ventrolateral medulla AT1 receptors support blood pressure in hypertensive rats. Hypertension. 2002;40:552.
15. Ito S, Hiratsuka M, Komatsu K, Tsukamoto K, Kanmatsuse K, Sved AF. Ventrolateral Medulla AT1 Receptors Support Arterial Pressure in Dahl Salt-Sensitive Rats. Hypertension. 2003;41:744.
16. Kashihara K, McMullan S, Lonergan T, Goodchild AK, Pilowsky PM. Neuropeptide Y in the rostral ventrolateral medulla blocks somatosympathetic reflexes in anesthetized rats. Autonomic Neuro - science: Basic and Clinical. 2008;142(1-2): 64-70.
17. Lauterio TJ, Bond JP, Ulman EA. Development and characterization of a purified diet to identify obesitysusceptible and resistant rat population. Journal of Nutrition. 1994;124:2172-2178.
18. Lohmeier TE, Warren S, Cunningham JT. Sustained activation of the central baroreceptor pathway in the obesity hypertension. Hypertension. 2003;42:96-102.
19. Mayorov DN, Head GA. Glutamate receptors in RVLM modulate sympathetic baroreflex in conscious rabbits. Am J Physiol Integr Comp Physiol. 2003;284: R511-R519.
20. Menezes R C A, Fontes M A P. Cardiovascular effects produced by activation of GABA receptors in the rostral ventrolateral medulla of conscious rats. Neuroscience. 2007;144(1):336-343.
21. Oshima N, McMullan S, Goodchild AK, Pilowsky PM. A monosynaptic connection between baroinhibited neurons in the RVLM and IML in Sprague-Dawley rats. Brain Research. 2006;1089:153-161.
22. Paxinos G, Watson C. The rat brain in stereotaxic coordinates, 2nd ed. Academic Press, New York, 1986.
23. Potts PD, Allen AM, Horiuchi J, Dampney R A L. Does angiotensin II have a significant tonic action on cardiovascular neurons in the rostral and caudal VLM. AM J Physiol Regulatory Integrative Comp Physiol. 2000;279: R1392-R1402.
24. Ross CA, Ruggiero DA, Park DH, Joh TH, Sved AF, Fernandez-Pardal J, et al. Tonic vasomotor control by the rostral ventrolateral medulla:effect of electrical or chemical stimulation of the area containing C1 adrenaline neurons on arterial pressure, heart rate, and plasma catecholamines and vasopressin. The Journal of Neuroscience. 1984;4(2):474-494.
25. Schreihofer AM, Mandel DA, Mobley SC, Stepp DW. Impairment of sympathetic baroreceptor reflexes in obese Zucker rats. Am J Physiol Heart Circ Physiol. 2007;293: H2543-H2549.
26. Stocker SD, Meador R, Adams JM. Neurons of the Rostral Ventrolateral Medulla Contribute to Obesity-Induced Hypertension in Rats. Hyper tension. 2007;49 [part 2]: 1-7.
27. Sved AF, Ito S, Madden CJ, Stocker SD, Yajima Y. Excitatory inputs to the RVLM in the context of the baroreceptor reflex. Annals of the New York Academy Sciences. 2001;940.
28. Sved AF, Ito S, Yajima Y. Role of excitatory amoni acid inputs to the rostral ventrolateral medulla in cardiovascular regulation. Clinical and Experimental Pharmacology and Physiology. 2002;29:503-506.
29. Tagawa T, Dampney R A L. AT1 receptors mediate excitatory inputs to rostral ventrolateral medulla pressor neurons from hypothalamus. Hypertension. 1999;34:1301.
30. Tsuchihashi T, Abe I, Fujishima M. Role of metabotropic glutamate receptors in ventrolateral medulla of hypertensive rats. Hypertension. 1994;24:648-652.
31. Yang Z, Coote JH. Influence of the hypothalamic paraventrivular nucleus on cardiovascular neurons in the rostral ventrolateral medulla of the rat. The Journal of Physiology. 1998;513:521-530.
32. Yang Z, Bertram D, Coote JH. The role of glutamate and vasopressin in the excitation of RVL neurons by paraventricular neurons. Brain Research. 2001;908(1):99-103.
33. Yusof A P M, Coote JH. Patterns of activity in sympathetic postganglionic nerves to skeletal muscle, skin and kidney during stimulation of the medullary raphe area of the rat. Journal of the Autonomic Nervous System. 1988;24(1-2): 71-9.
34. Yusof A P M. Central control of blood pressure. Malaysian Journal of Pharmaceutical Sciences. 2007;5(1): v-viii.
35. Yusof A P M, Yusoff N H M, Suhaimi FW, Coote JH. Role of supraspinal vasopressin neurons in the effects of atrial natriuretic peptide on sympathetic nerve activity. Autonomic Neuroscience: Basic and Clinical. 2009;148:50-54.