Interleukin 21 expression is increased in rectal biopsies from patients with ulcerative colitis

Inflammatory Bowel Diseases

Volumn 16, Issue 7, 2010, Pages 1090-

  Yamamoto Furusho, Jesús K ^a   Miranda Pérez, Elizabeth ^a   Fonseca Camarillo, Gabriela ^a   Sánchez Muñoz, Fausto ^a   Barreto Zuñiga, Rafael ^a   Dominguez Lopez, Aarón ^a  

^a INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 21;

CROHN DISEASE; ENTERITIS; GENE EXPRESSION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HUMAN; LETTER; PRIORITY JOURNAL; RECTUM BIOPSY; TH1 CELL; ULCERATIVE COLITIS;

BIOPSY; COLITIS, ULCERATIVE; HUMANS; INTERLEUKINS; RECTUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 77953721903     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1002/ibd.21135     Document Type: Letter

References (5)

1. Fantini MC, Monteleone G, Macdonald TT. New players in the cytokine orchestra of inflammatory bowel disease. Inflamm Bowel Dis. 2007;13:1419-1423.
2. Monteleone G, Monteleone I, Fina D, et al. Interleukin-21 enhances T-helper cell type I signaling and interferon-gamma production in Crohn's disease. Gastroenterology. 2005;128:687-694. (Pubitemid 40585371)
3. Festen EA, Goyette P, Scott R, et al. Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis. Gut. 2009;58:799-804.
4. Márquez A, Orozco G, Martínez A, et al. Novel association of the interleukin 2-interleukin 21 region with inflammatory bowel disease. Am J Gastroenterol. 2009;104:1968-1975.
5. Liu Z, Yang L, Cui Y, et al. IL-21 enhances NK cell activation and cytolytic activity and induces Th17 cell differentiation in inflammatory bowel disease. Inflamm Bowel Dis. 2009;15:1133-1144.