Combination of conventional multiplex PCR and quantitative real-time PCR detects large rearrangements in the dystrophin gene in 59% of Syrian DMD/BMD patients

Clinical Biochemistry

Volumn 43, Issue 10-11, 2010, Pages 836-842

  Madania, Ammar ^a   Zarzour, Hana ^a   Jarjour, Rami A ^a   Ghoury, Ifad ^a  

^a DEPARTMENT OF MOLECULAR BIOLOGY AND BIOTECHNOLOGY   (Syrian Arab Republic)

Author keywords

Carrier detection; Duchenne muscular dystrophy (DMD); Dystrophin; Gene rearrangement; Multiplex PCR; Real time PCR; The Ct method

Indexed keywords

DYSTROPHIN; GENOMIC DNA;

ADOLESCENT; ADULT; ARTICLE; BECKER MUSCULAR DYSTROPHY; CHILD; CONTROLLED STUDY; DIAGNOSTIC VALUE; DNA ISOLATION; DUCHENNE MUSCULAR DYSTROPHY; EXON; FEMALE; GENE DELETION; GENE DUPLICATION; GENE FUNCTION; GENE REARRANGEMENT; HETEROZYGOTE DETECTION; HUMAN; INSTRUMENT VALIDATION; MAJOR CLINICAL STUDY; MALE; MULTIPLEX POLYMERASE CHAIN REACTION; MUTATIONAL ANALYSIS; PRESCHOOL CHILD; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SCHOOL CHILD; SYRIAN ARAB REPUBLIC; GENETICS; INFANT; MUSCULAR DYSTROPHY, DUCHENNE; MUTATION; NUCLEOTIDE SEQUENCE; PROCEDURES; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; DNA MUTATIONAL ANALYSIS; DYSTROPHIN; HUMANS; INFANT; MALE; MUSCULAR DYSTROPHY, DUCHENNE; MUTATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SYRIA;

EID: 77953701827     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2010.03.014     Document Type: Article

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