Therapy with sildenafil or bosentan decreases pulmonary vascular resistance in patients ineligible for heart transplantation because of severe pulmonary hypertension

Journal of Heart and Lung Transplantation

Volumn 29, Issue 7, 2010, Pages 817-818

  Perez Villa, Felix ^a   Farrero, Marta ^a   Sionis, Alessandro ^a   Castel, Angeles ^a   Roig, Eulalia ^a  

^a HOSPITAL CLÍNIC   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BOSENTAN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; NITROPRUSSIDE SODIUM; SILDENAFIL; SPIRONOLACTONE;

ANGIONEUROTIC EDEMA; CLINICAL TRIAL; DIURETIC THERAPY; DRUG DOSE TITRATION; DRUG WITHDRAWAL; HEART CATHETERIZATION; HEART FAILURE; HEART TRANSPLANTATION; HEART VENTRICLE TACHYCARDIA; HUMAN; HYPERTENSION; LETTER; LUNG ARTERY PRESSURE; LUNG VASCULAR RESISTANCE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PULMONARY HYPERTENSION; TREATMENT REFUSAL;

ADMINISTRATION, ORAL; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; HEART FAILURE; HEART TRANSPLANTATION; HUMANS; HYPERTENSION, PULMONARY; PIPERAZINES; PROSPECTIVE STUDIES; PURINES; RETROSPECTIVE STUDIES; SULFONAMIDES; SULFONES; VASCULAR RESISTANCE; VASODILATOR AGENTS;

EID: 77953700669     PISSN: 10532498     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.healun.2010.02.004     Document Type: Letter

References (5)

1. Taylor D.O., Stehlik J., Edwards L.B., et al. The registry of the International Society of Heart and Lung Transplantation: twenty-sixth official adult heart transplant report-2009. J Heart Lung Transplant 28 (2009) 1007-1022
2. Torre-Amione G., Southard R.E., Loebe M.M., et al. Reversal of secondary pulmonary hypertension by axial and pulsatile mechanical circulatory support. J Heart Lung Transplant 29 (2010) 195-200
3. Costard-Jackle A., and Fowler M.B. Influence of preoperative pulmonary artery pressure on mortality after heart transplantation: testing of potential reversibility of pulmonary hypertension with nitroprusside is useful in defining a high-risk group. J Am Coll Cardiol 19 (1992) 48-54
4. Galie N., Beghetti M., Gatzoulis M.A., et al. Bosentan therapy in patients with Eisenmenger syndrome. A multicenter, double-blind, randomized, placebo-controlled study. Circulation 114 (2006) 48-54
5. Lewis G.D., Shah R., Shahzad K., et al. Sildenafil improves exercise capacity and quality of life in patients with systolic heart failure and secondary pulmonary hypertension. Circulation 116 (2007) 1555-1562