Dissemination of two international linezolid-resistant Staphylococcus epidermidis clones in Greek hospitals

Journal of Antimicrobial Chemotherapy

Volumn 65, Issue 5, 2010, Pages 1070-1071

  Liakopoulos, A ^a   Spiliopoulou, I ^b   Damani, A ^a   Kanellopoulou, M ^c   Schoina, S ^b   Papafragas, E ^c   Marangos, M ^b   Fligou, F ^b   Zakynthinos, E ^d   Makris, D ^d   Protonotariou, E ^e   Tsiapara, F ^e   Filos, K ^b   Diza, E ^e   Anastassiou, E D ^b   Petinaki, E ^a  

^a UNIVERSITY OF THESSALY   (Greece)

^b UNIVERSITY OF PATRAS   (Greece)

^c SISMANOGLIO HOSPITAL   (Greece)

^d UNIVERSITY HOSPITAL OF LARISSA   (Greece)

^e AHEPA UNIVERSITY HOSPITAL   (Greece)

Author keywords

Greece; Multilocus sequence typing; Mutations; Staphylococci

Indexed keywords

ANTIINFECTIVE AGENT; CEFOXITIN; CIPROFLOXACIN; CLINDAMYCIN; DALFOPRISTIN; DAPTOMYCIN; ERYTHROMYCIN; FUSIDIC ACID; GENTAMICIN; LINEZOLID; OXACILLIN; PENICILLIN G; QUINUPRISTIN; RIFAMPICIN; TEICOPLANIN; TETRACYCLINE; TIGECYCLINE; TOBRAMYCIN; VANCOMYCIN; ACETAMIDE DERIVATIVE; BACTERIAL PROTEIN; OXAZOLIDINONE DERIVATIVE;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ANTIBIOTIC THERAPY; BACTERIAL GENE; BACTERIAL STRAIN; GENE MUTATION; GREECE; HOSPITAL; HUMAN; LETTER; MULTIDRUG RESISTANCE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; STAPHYLOCOCCUS EPIDERMIDIS; ADULT; AGED; BACTERIUM IDENTIFICATION; CLASSIFICATION; CLUSTER ANALYSIS; CROSS INFECTION; DNA FINGERPRINTING; DNA SEQUENCE; DRUG EFFECT; GENETICS; GENOTYPE; ISOLATION AND PURIFICATION; MALE; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; MIDDLE AGED; MISSENSE MUTATION; POINT MUTATION; STAPHYLOCOCCUS INFECTION;

ACETAMIDES; ADULT; AGED; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BACTERIAL TYPING TECHNIQUES; CLUSTER ANALYSIS; CROSS INFECTION; DNA FINGERPRINTING; DRUG RESISTANCE, BACTERIAL; GENOTYPE; GREECE; HOSPITALS; HUMANS; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; MUTATION, MISSENSE; OXAZOLIDINONES; POINT MUTATION; SEQUENCE ANALYSIS, DNA; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS EPIDERMIDIS; YOUNG ADULT;

EID: 77953696182     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkq065     Document Type: Letter

References (6)

1. Liakopoulos A, Neocleous C, Klapsa D et al. A T2504A mutation in the 23S rRNA gene responsible for high-level resistance to linezolid of Staphylococcus epidermidis. J Antimicrob Chemother 2009; 64: 206-7.
2. Lincopan N, de Almeida LM, Elmor de Araújo MR et al. Linezolid resistance in Staphylococcus epidermidis associated with a G2603T mutation in the 23S rRNA gene. Int J Antimicrob Agents 2009; 34: 281-2.
3. Wong A, Reddy SP, Smyth DS et al. Polyphyletic emergence of linezolid-resistant staphylococci in the United States. Antimicrob Agents Chemother 2010; 54: 742-8.
4. Mendes RE, Deshpande LM, Castanheira M et al. First report of cfr-mediated resistance to linezolid in human staphylococcal clinical isolates recovered in the United States. Antimicrob Agents Chemother 2008; 52: 2244-6.
5. Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing: Nineteenth Informational Supplement M100-S19. CLSI, Wayne, PA, USA, 2009.
6. Thomas JC, Vargas MR, Miragaia M et al. An improved multilocus sequence typing scheme for Staphylococcus epidermidis. J Clin Microbiol 2007; 45: 616-9.