Subjective Perception of Lactose Intolerance Does Not Always Indicate Lactose Malabsorption

Clinical Gastroenterology and Hepatology

Volumn 8, Issue 7, 2010, Pages 581-586

  Casellas, Francesc ^a   Aparici, Anna ^a   Casaus, Maite ^a   Rodríguez, Purificación ^a   Malagelada, Juan R ^a  

^a HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

Author keywords

Hydrogen Breath Test; Lactase Activity; Lactose Intolerance; Lactose Malabsorption

Indexed keywords

ARTICLE; DAIRY PRODUCT; FEMALE; HUMAN; HYDROGEN BREATH TEST; LACTOSE INTOLERANCE; MAJOR CLINICAL STUDY; MALE; PROSPECTIVE STUDY; QUESTIONNAIRE; ADULT; BREATH ANALYSIS; CROSSOVER PROCEDURE; METABOLISM; PATHOLOGY; PERCEPTION; PSYCHOLOGY;

ADULT; BREATH TESTS; CROSS-OVER STUDIES; FEMALE; HUMANS; LACTOSE; LACTOSE INTOLERANCE; MALE; PERCEPTION; PROSPECTIVE STUDIES; QUESTIONNAIRES; SURVEYS AND QUESTIONNAIRES;

LACTOSE;

EID: 77953687752     PISSN: 15423565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cgh.2010.03.027     Document Type: Article

References (25)

1. Melvin B.H., and Committee on Nutrition. Lactose intolerance in infants, children and adolescents. Pediatrics 118 (2006) 1279-1286
2. Iqbal T.H., Bradley R., Reilly K.O., et al. Small intestinal lactase status, frequency distribution of enzyme activity and milk intake in a multi-ethnic population. Clin Nutr 15 (1996) 297-302
3. Gupta S.K., Chong S.K.F., and Fitzgerald J.F. Disaccharidase activities in children: normal values and comparison based on symptoms and histologic changes. J Pediatr Gastroenterol Nutr 28 (1999) 246-251
4. Suarez F.L., Savaiano D.A., and Levitt M.D. A comparison of symptoms after the consumption of milk or lactose-hydrolyzed milk by people with self-reported severe lactose intolerance. N Engl J Med 333 (1995) 1-4
5. Leis R., Tojo R., Pavón P., et al. Prevalence of lactose malabsorption in Galicia. J Pediatr Gastroenterol Nutr 25 (1997) 296-300
6. Vernia P., Camillo M., Marinaro V., et al. Lactose malabsorption and the genesis of irritable bowel syndrome symptoms. Gastroenterology 120 Suppl 1 (2001) A264
7. Vonk R.J., Priebe M.G., Koetse H.A., et al. Lactose intolerance: analysis of underlying factors. Eur J Clin Invest 33 (2003) 70-75
8. Martini M.C., and Savaiano D.A. Reduced intolerance symptoms from lactose consumed during a meal. Am J Clin Nutr 47 (1988) 57-60
9. He T., Priebe M.G., Harmsen H.J., et al. Colonic fermentation may play a role in lactose intolerance in humans. J Nutr 136 (2006) 58-63
10. Vesa T.H., Korpela R.A., and Sahi T. Tolerance to small amounts of lactose in lactose maldigesters. Am J Clin Nutr 64 (1996) 197-201
11. Vernia P., Marinaro V., Argnani F., et al. Self-reported milk intolerance in irritable bowel syndrome: what should we believe?. Clin Nutr 23 (2004) 996-1000
12. Birge Jr. S.J., Keutmann H.T., Cuatrecasas P., et al. Osteoporosis, intestinal lactase deficiency and low dietary calcium intake. N Engl J Med 276 (1967) 445-448
13. Jackson K.A., and Savaiano D.A. Lactose maldigestion, calcium intake and osteoporosis in African-, Asian-, and Hispanic-Americans. J Am Coll Nutr 20 Suppl 2 (2001) 198S-207S
14. Casellas F., and Malagelada J.R. Applicability of short hydrogen breath test for screening of lactose malabsorption. Dig Dis Sci 48 (2003) 1333-1338
15. Peuhkuri K., Vapaatalo H., Nevala R., et al. Temperature of a test solution influences abdominal symptoms in lactose tolerance tests. Scand J Clin Lab Invest 60 (2000) 75-80
16. Casellas F., Varela E., Aparici A., et al. Development, validation and applicability of a symptoms questionnaire for lactose malabsorption screening. Dig Dis Sci 54 (2009) 1059-1065
17. Casado A., Prieto L., and Alonso J. El tamaño del efecto de la diferencia entre dos medias: ¿estadísticamente significativo o clínicamente relevante?. Med Clin 112 (1999) 584-588
18. Malagelada J.R. Lactose intolerance. N Engl J Med 333 (1995) 53-54
19. Lacassie Y., Weinberg R., and Mönckeberg F. Poor predictability of lactose malabsorption from clinical symptoms for Chilean populations. Am J Clin Nutr 31 (1978) 799-804
20. Sciarretta G., Giacobazzi G., Verri A., et al. Hydrogen breath test quantification and clinical correlation of lactose malabsorption in adult irritable bowel syndrome and ulcerative colitis. Dig Dis Sci 29 (1984) 1098-1104
21. Suarez F., and Levitt M.D. Abdominal symptoms and lactose: the discrepancy between patients' claims and the results of blinded trials. Am J Clin Nutr 64 (1996) 251-252
22. Farup P.G., Monsbakken K.W., and Vandvik P.O. Lactose malabsorption in a population with irritable bowel syndrome: prevalence and symptoms-a case-control study. Scand J Gastroenterol 39 (2004) 645-649
23. Bernstein C.N., Ament M., Artinian L., et al. Milk tolerance in adults with ulcerative colitis. Am J Gastroenterol 89 (1994) 872-877
24. Ginard D., Riera J., Barranco L., et al. Lactose malabsorption in ulcerative colitis: a case-control study. Gastroenterol Hepatol 26 (2003) 469-474
25. Savaiano D.A., Boushey C.J., and McCabe G.P. Lactose intolerance symptoms assessed by meta-analysis: a grain of truth that leads to exaggeration. J Nutr 136 (2006) 1107-1113