Long-term outcome of adult acute lymphoblastic leukemia in Lebanon: A single institution experience from the American University of Beirut

Hematology/ Oncology and Stem Cell Therapy

Volumn 2, Issue 2, 2009, Pages 333-339

  Charafeddine, Khalil M ^a   Hatoum, Hassan A ^a   Otrock, Zaher K ^a   Mahfouz, Rami A ^a   Salem, Ziad M ^a   Shamseddine, Ali I ^a   Taher, Ali T ^a   El Saghir, Nagi S ^a   Bazarbachi, Ali ^a  

^a AMERICAN UNIVERSITY OF BEIRUT   (Lebanon)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BLEOMYCIN; CARBOPLATIN; CYCLOPHOSPHAMIDE; DOXORUBICIN; FLUOROURACIL; METHOTREXATE; VINCRISTINE;

ACUTE LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ADULT; AGED; ARTICLE; CENTRAL NERVOUS SYSTEM DISEASE; DEVELOPING COUNTRY; DISEASE FREE SURVIVAL; DRUG FATALITY; FEMALE; HUMAN; LEBANON; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PROGNOSIS; REMISSION; RETROSPECTIVE STUDY; RISK FACTOR; STEM CELL TRANSPLANTATION; TERTIARY HEALTH CARE; TREATMENT DURATION; TREATMENT RESPONSE; UNIVERSITY HOSPITAL; CLINICAL TRIAL; INTRASPINAL DRUG ADMINISTRATION; MIDDLE AGED; PATHOLOGY; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; SURVIVAL RATE; TIME; TREATMENT OUTCOME; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; FEMALE; HUMANS; INJECTIONS, SPINAL; LEBANON; MALE; MIDDLE AGED; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; REMISSION INDUCTION; RETROSPECTIVE STUDIES; SURVIVAL RATE; TIME FACTORS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 77953680360     PISSN: 16583876     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1658-3876(09)50021-0     Document Type: Article

References (36)

1. Jemal A, Siegel R, Ward E, Murray T, Xu J, Smigal C, et al. Cancer statistics, 2006. CA Cancer J Clin 2006;56:106-130.
2. Annino l, Goekbuget N, Delannoy A. Acute lymphoblastic leukemia in the elderly. Hematol J 2002;3:219-223.
3. Deschler b, lubbert M. acute myeloid leukemia: epidemiology and etiology. Cancer. 2006;107:2099-2107.
4. Secker-Walker LM. Distribution of Philadelphia positive acute lymphoblastic leukemia: geographical heterogeneity or age related incidence? Genes Chromosomes Cancer 1991;3:320-321.
5. Hunault M, Harousseau Jl, Delain M, Truchan-Graczyk M, Cahn JY, Witz F, et al. Better outcome of adult acute lymphoblastic leukemia after early genoidentical allogeneic bone marrow transplantation (BMT) than after late high-dose therapy and autologous BMT: a GOELAMS trial. Blood 2004;104:3028-3037. (Pubitemid 39507116)
6. Jemal A, Tiwari RC, Murray T, Ghafoor A, Samuels A, Ward E, et al. Cancer statistics, 2004. CA Cancer J Clin 2004;54:8-29.
7. Yahya HI, Al-allawi NA, Mattar Y. Acute lympoblastic Leukaemia in seventy Iraqi adults: clinical and haematological findings and outcome of therapy. Indian J Cancer 2000;37:85-90.
8. Fogliatto l, bittencourt H, Nunes AS, Salenave PR, Silva GS, Daudt LE, et al. Outcome of treatment in adult acute lymphoblastic leukemia in southern Brazil using a modified german multicenter acute lymphoblastic leukemia protocol. Acta Haematol 2002;107:203-207.
9. Gokbuget N, Hoelzer D. Treatment of adult acute lymphoblastic leukemia. Hematology Am Soc Hematol Educ Program 2006:133-141.
10. Wetzler M, Dodge RK, Mrozek K, Carroll AJ, Tantravahi R, Block AW, et al. Prospective karyotype analysis in adult acute lymphoblastic leukemia: the cancer and leukemia Group B experience. Blood 1999;93:3983-3993. (Pubitemid 29249848)
11. Thomas X, Danaila C, LE QH, Sebban C, Troncy J, Charrin C, et al. long-term follow-up of patients with newly diagnosed adult acute lymphoblastic leukemia: a single institution experience of 378 consecutive patients over a 21-year period. Leukemia 2001;15:1811-1822. (Pubitemid 33114986)
12. Thomas X, Le QH. Prognostic factors in adult acute lymphoblastic leukemia. Hematology 2003;8:233-242.
13. Le QH, Thomas X, Ecochard R, Iwaz J, lheritier V, Michallet M, et al. Initial and late prognostic factors to predict survival in adult acute lymphoblastic leukaemia. Eur J Haematol 2006;77:471-479.
14. Ellison RR, Mick R, Cuttner J, Schiffer CA, Silver RT, Henderson ES, et al. The effects of postinduction intensification treatment with cytarabine and daunorubicin in adult acute lymphocytic leukemia: a prospective randomized clinical trial by Cancer and Leukemia Group B. J Clin Oncol 1991;9:2002-2015.
15. Durrant IJ, Richards SM, Prentice HG, Goldstone AH. The Medical Research Council trials in adult acute lymphocytic leukemia. Hematol Oncol Clin North Am 2000;14:1327-1352.
16. Takeuchi J, Kyo T, naito K, Sao H, Takahashi M, Miyawaki S, et al. Induction therapy by frequent administration of doxorubicin with four other drugs, followed by intensive consolidation and maintenance therapy for adult acute lymphoblastic leukemia: the JAlSG-ALL93 study. Leukemia 2002;16:1259-1266.
17. Rowe JM, Buck G, Burnett AK, Chopra R, Wiernik PH, Richards SM, et al. Induction therapy for adults with acute lymphoblastic leukemia: results of more than 1500 patients from the international ALL trial: MRC UKALL XII/ECOG E2993. Blood 2005;106:3760-3767. (Pubitemid 41739010)
18. Larson RA, Dodge RK, Linker CA, Stone RM, Powell BL, Lee EJ, et al. A randomized controlled trial of filgrastim during remission induction and consolidation chemotherapy for adults with acute lymphoblastic leukemia: CALGB study 9111. Blood 1998;92:1556-1564.
19. Kantarjian H, Thomas D, O'brien S, Cortes J, Giles F, Jeha S, et al. Long-term follow-up results of hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone (Hyper-CVAD), a dose-intensive regimen, in adult acute lymphocytic leukemia. Cancer 2004;101:2788-2801.
20. Annino L, Vegna ML, Camera A, Specchia G, Visani G, Fioritoni G, et al. Treatment of adult acute lymphoblastic leukemia (ALL): long-term follow-up of the GIMEMA ALL 0288 randomized study. Blood 2002;99:863-871.
21. bennett JM, Catovsky D, Daniel MT, Flandrin G, Galton DA, Gralnick HR, et al. Proposals for the classification of the acute leukaemias. French-American-British (FAB) co-operative group. Br J Haematol 1976;33:451-458
22. Kaplan ER, Meier P. Non-parametric estimation from in complete observations. J Am Stat assoc 1958;53:457-481.
23. Schrauder A, Reiter A, Gadner H, Niethammer D, Klingebiel T, Kremens B, et al. Superiority of allogeneic hematopoietic stem-cell transplantation compared with chemotherapy alone in high-risk childhood T-cell acute lymphoblastic leukemia: results from ALL-BFM 90 and 95. J Clin Oncol 2006;24:5742-5749. (Pubitemid 46631317)
24. Kantarjian HM, O'brien S, Smith TL, Cortes J, Giles FJ, beran M, et al. Results of treatment with hyper-CVAD, a dose-intensive regimen, in adult acute lymphocytic leukemia. J Clin Oncol 2000;18:547-561.
25. Mancini M, Scappaticci D, Cimino G, Nanni M, Derme V, Elia L, et al. A comprehensive genetic classification of adult acute lymphoblastic leukemia (ALL): analysis of the GIMEMA 0496 protocol. Blood 2005;105:3434-3441
26. Eden OB, Harrison G, Richards S, Lilleyman JS, Bailey CC, Chessells JM, et al. Long-term follow-up of the United Kingdom Medical Research Council protocols for childhood acute lymphoblastic leukaemia, 1980-1997. Medical Research Council Childhood Leukaemia Working Party. Leukemia 2000;14:2307-2320.
27. Schrappe M, Reiter A, Zimmermann M, Harbott J, Ludwig WD, Henze G, et al. Long-term results of four consecutive trials in childhood all performed by the ALL-BFM study group from 1981 to 1995. Berlin-Frankfurt-Munster. Leukemia 2000;14:2205-2222.
28. Horowitz MM, Messerer D, Hoelzer D, Gale RP, Neiss A, Atkinson K, et al. Chemotherapy compared with bone marrow transplantation for adults with acute lymphoblastic leukemia in first remission. Ann Intern Med 1991;115:13-18.
29. Hoelzer D, Thiel E, Loffler H, Buchner T, Ganser A, Heil G, et al. Prognostic factors in a multicenter study for treatment of acute lymphoblastic leukemia in adults. Blood 1988;71:123-131. (Pubitemid 18050401)
30. Beutler E. Platelet transfusions: the 20,000/microL trigger. Blood 1993;81:1411-1413.
31. Hoelzer D, Gokbuget N, Digel W, Faak T, Kneba M, Reutzel R, et al. Outcome of adult patients with T-lymphoblastic lymphoma treated according to protocols for acute lymphoblastic leukemia. Blood 2002;99:4379-4385. (Pubitemid 34627204)
32. Degos l, Linch D, Lowenberg B. Textbook of Malignant Hematology 2nd edition ed. London: Informa HealthCare; 1 edition (July 1, 2003), 2004.
33. Pui CH, Evans WE. Treatment of acute lymphoblastic leukemia. n engl J Med 2006;354:166-178.
34. Thiebaut A, Vernant JP, Degos L, Huguet FR, Reiffers J, Sebban C, et al. Adult acute lymphocytic leukemia study testing chemotherapy and autologous and allogeneic transplantation. A follow-up report of the French protocol LALA 87. Hematol Oncol Clin North Am 2000;14:1353-1366, x.
35. Cytogenetic abnormalities in adult acute lymphoblastic leukemia: correlations with hematologic findings outcome. A Collaborative Study of the Group Francais de Cytogenetique Hematologique. Blood 1996;87:3135-3142.
36. Faderl S, Kantarjian HM, Talpaz M, Estrov Z. Clinical significance of cytogenetic abnormalities in adult acute lymphoblastic leukemia. Blood 1998;91:3995-4019. (Pubitemid 28261960)