Formula induces intestinal apoptosis in preterm pigs within a few hours of feeding

Journal of Parenteral and Enteral Nutrition

Volumn 34, Issue 3, 2010, Pages 271-279

  Oste, Marijke ^a   Van Haver, Els ^a   Thymann, Thomas ^b   Sangild, Per ^b   Weyns, André ^a   Van Ginneken, Christa J ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Colostrum; Enteral feeding; Formula; Preterm; Short term

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ARTIFICIAL MILK; ATROPHY; CELL PROLIFERATION; CELL VOLUME; COLOSTRUM; CONTROLLED STUDY; CRYPT CELL; ENTERIC FEEDING; NECROTIZING ENTEROCOLITIS; NEWBORN; NONHUMAN; PARENTERAL NUTRITION; PIGLET; PRIORITY JOURNAL; SMALL INTESTINE MUCOSA; ANIMAL; CYTOLOGY; ELEMENTAL DIET; ENTEROCOLITIS, NECROTIZING; FEMALE; INTESTINE MUCOSA; PATHOLOGY; PREGNANCY; SMALL INTESTINE; SWINE;

SUIDAE;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; CELL PROLIFERATION; COLOSTRUM; ENTERAL NUTRITION; ENTEROCOLITIS, NECROTIZING; FEMALE; FOOD, FORMULATED; INTESTINAL MUCOSA; INTESTINE, SMALL; PARENTERAL NUTRITION; PREGNANCY; SWINE;

EID: 77953673063     PISSN: 01486071     EISSN: None     Source Type: Journal    
DOI: 10.1177/0148607109337540     Document Type: Article

References (35)

1. Jensen AR, Elnif J., Burrin DG, Sangild PT Development of intestinal immunoglobulin absorption and enzyme activities in neonatal pigs is diet dependent. J Nutr. 2001 ; 131: 3259-3265.
2. Schwarz SM, Heird WC Effects of feeding on the small intestinal mucosa of beagle pups during the first 5 days of life. Am J Clin Nutr. 1994 ; 60: 879-886.
3. Widdowson EM Changes in the body and its organs during lactation: nutritional implications. Ciba Found Symp. 1976 ; 103-118.
4. Oste M., Van Ginneken C., Van Haver E., Bjornvad CR, Thymann T., Sangild PR The intestinal trophic response to enteral food is reduced in parenterally fed preterm pigs and is associated with more nitrergic neurons. J Nutr. 2005 ; 135: 2657-2663.
5. Burrin DG, Davis TA, Ebner S., et al. Nutrient-independent and nutrient-dependent factors stimulate protein synthesis in colostrum-fed newborn pigs. Pediatr Res. 1995 ; 37: 593-599.
6. Burrin DG, Shulman RJ, Reeds PJ, Davis TA, Gravitt KR Porcine colostrum and milk stimulate visceral organ and skeletal muscle protein synthesis in neonatal piglets. J Nutr. 1992 ; 122: 1205-1213.
7. Zhang H., Malo C., Buddington RK Suckling induces rapid intestinal growth and changes in brush border digestive functions of newborn pigs. J Nutr. 1997 ; 127: 418-426.
8. Sangild PR, Bjà¶rnvad CR, Petersen YM, Elnif J., Burrin DG Spontaneous NEC-like symptoms in formula-fed premature pigs. Gastroenterology. 2002 ; 122: A341.
9. McGuire W., Henderson G., Fowlie PW Feeding the preterm infant. BMJ. 2004 ; 329: 1227-1230.
10. Darragh AJ, Moughan PJ The amino acid composition of human milk corrected for amino acid digestibility. Br J Nutr. 1998 ; 80: 25-34.
11. Xu RJ, Mellor DJ, Tungthanatanich P., Birtles MJ, Reynolds GW, Simpson HV Growth and morphological changes in the small and large intestine in piglets during the first three days after birth. J Dev Physiol. 1992 ; 18: 161-172.
12. Wolinski J., Biernat M., Guilloteau P., Westrom BR, Zabielski R. Exogenous leptin controls the development of the small intestine in neonatal piglets. J Endocrinol. 2003 ; 177: 215-222.
13. Biernat M., Wolinski J., Godlewski MM, Motyl T., Morisset J., Zabielski R. Apoptosis in the gut of neonatal piglets. In: Proceedings of the 9th International Symposium on Digestive Physiology in Pigs ; May 14-17, 2003 ; Banff, Alberta, Canada.
14. Sangild PT Gut responses to enteral nutrition in preterm infants and animals. Exp Biol Med. 2006 ; 231: 1695-1711.
15. Neu J., Weiss MD Necrotizing enterocolitis: pathophysiology and prevention. JPEN J Parenter Enteral Nutr. 1999 ; 23 (5 suppl). S13 - S17.
16. Kliegman RM, Fanaroff AA Necrotizing enterocolitis. N Engl J Med. 1984 ; 310: 1093-1103.
17. McGuire W., Henderson G., Fowlie PW Feeding the preterm infant. BMJ. 2004 ; 329: 1226-1230.
18. Scolapio JS A review of the trends in the use of enteral and parenteral nutrition support. J Clin Gastroenterol. 2004 ; 38: 403-407.
19. Rouwet EV, Heineman E., Buurman WA, ter Riet G., Ramsay G., Blanco CE Intestinal permeability and carrier-mediated monosaccharide absorption in preterm neonates during the early postnatal period. Pediatr Res. 2002 ; 51: 64-70.
20. Niinikoski H., Stoll B., Guan X., et al. Onset of small intestinal atrophy is associated with reduced intestinal blood flow in TPN-fed neonatal piglets. J Nutr. 2004 ; 134: 1467-1474.
21. Sangild PT, Schmidt M., Elnif J., Bjornvad CR, Buddington RK Prenatal development of the gastrointestinal tract in pigs and the effect of fetal gut obstruction. Ped Res. 2002 ; 52: 416-424.
22. Sangild PR, Petersen YM, Schmidt M., et al. Preterm birth affects the intestinal response to parenteral and enteral nutrition in newborn pigs. J Nutr. 2002 ; 132: 2673-2681.
23. Sangild PT, Xu RJ Colostrum. In: Encyclopedia of Animal Science. New York: Marcel Dekker ; 2004: 1-3.
24. Dvorak B., Halpern MD, Holubec H., et al. Epidermal growth factor reduces the development of necrotizing enterocolitis in a neonatal rat model. Am J Physiol. 2002 ; 282: G156 - G164.
25. Gundersen HJG, Jensen EB The efficiency of systematic sampling in stereology and its prediction. J Microsc. 1987 ; 147: 229-263.
26. Wright N., Watson A., Morley A., Appleton D., Marks J. Cell kinetics in flat (avillous) mucosa of the human small intestine. Gut. 1973 ; 14: 701-710.
27. Burrin DG Is milk-born insulin-like growth factor-1 essential for neonatal development? J Nutr. 1997 ; 127: 975S - 979S.
28. Zhang H., Malo C., Boyle CR, Buddington RK Diet influences development of the pig (Sus Scrofa) intestine during the first 6 hours after birth. J Nutr. 1998 ; 128: 1302-1310.
29. Van Ginneken C., Van Meir F., Sys S., Weyns A. Stereologic characteristics of pig small intestine during normal development. Dig Dis Sci. 2002 ; 47: 868-878.
30. Wang T., Xu RJ Effects of colostrum feeding on intestinal development in newborn pigs. Biol Neonate. 1996 ; 70: 339-348.
31. Bjà¶rnvad CR, Schmidt M., Petersen YM, et al. Preterm birth makes the immature intestine sensitive to feeding-induced intestinal atrophy. Am J Physiol. 2005 ; 289: R1212 - R1222.
32. Kliegman RM Neonatal necrotizing enterocolitis: implications for an infectious disease. Pediatr Clin North Am. 1979 ; 26: 327-344.
33. Updegrove K. Necrotizing enterocolitis: the evidence for use of human milk in prevention and treatment. J Hum Lact. 2004 ; 20: 353-339.
34. Kansagra K., Stoll B., Rognerud C., et al. Total parenteral nutrition adversely affects gut barrier function in neonatal piglets. Am J Physiol Gastrointest Liver Physiol. 2003 ; 285: G1162 - G1170.
35. Levine GM, Deren JJ, Steiger E., Zinno R. Role of oral intake in maintenance of gut mass and disaccharide activity. Gastroenterology. 1974 ; 67: 975-982.