The creation of the Comparative Oncology Trials Consortium Pharmacodynamic Core: Infrastructure for a virtual laboratory

Veterinary Journal

Volumn 185, Issue 1, 2010, Pages 88-89

  Paoloni, Melissa ^a   Lana, Susan ^b   Thamm, Douglas ^b   Mazcko, Christina ^a   Withrow, Stephen ^b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b USA   (United States)

Author keywords

Biomarkers; Clinical trials; Pharmacodynamics; Pharmacokinetics

Indexed keywords

BIOLOGICAL MARKER;

ANIMAL HEALTH; ARTICLE; CLINICAL LABORATORY; DOG DISEASE; DRUG INDUSTRY; DRUG MECHANISM; DRUG RESEARCH; DRUG TARGETING; HUMAN; MEDICAL SERVICE; NONHUMAN; ONCOLOGY; PARTICIPATORY RESEARCH; PHARMACODYNAMICS; QUALITY CONTROL; QUALITY OF LIFE; VETERINARY MEDICINE;

ANIMALS; ANTINEOPLASTIC AGENTS; CLINICAL TRIALS AS TOPIC; DOG DISEASES; DOGS; NEOPLASMS; TREATMENT OUTCOME;

ANIMALIA; CANIS FAMILIARIS;

EID: 77953662408     PISSN: 10900233     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tvjl.2010.04.019     Document Type: Article

References (4)

1. Eckersall P.D., Slater K., Mobasheri A. Biomarkers in veterinary medicine: establishing a new international forum for veterinary biomarker research. Biomarkers 2009, 14:637-641.
2. Gordon I., Paoloni M., Mazcko C., Khanna C. The comparative oncology trials consortium: using spontaneously occurring cancers in dogs to inform the cancer drug development pathway. PLoS Med 2009, 6:e1000161.
3. Paoloni M., Khanna C. Translation of new cancer treatments from pet dogs to humans. Nature Review of Cancer 2008, 8:147-156.
4. Paoloni M.C., Tandle A., Mazcko C., Hanna E., Kachala S., Leblanc A., Newman S., Vail D., Henry C., Thamm D., Sorenmo K., Hajitou A., Pasqualini R., Arap W., Khanna C., Libutti S.K. Launching a novel preclinical infrastructure: comparative oncology trials consortium directed therapeutic targeting of TNFalpha to cancer vasculature. PLoS One 2009, 4:e4972.