Pharmacokinetics of dapoxetine hydrochloride in healthy Chinese, Japanese, and Caucasian men

Journal of Clinical Pharmacology

Volumn 50, Issue 12, 2010, Pages 1450-1460

  Thyssen, An ^a   Sharma, Om ^b   Tianmei, Si ^c   Aquilina, Joseph W ^b   Vandebosch, An ^a   Wang, Shean Sheng ^b   Mudumbi, Ramagopal ^b   Hsiao, Hsiu Ling ^b  

^a JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^b JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

^c PEKING UNIVERSITY SIXTH HOSPITAL   (China)

Author keywords

Asian; Caucasian; dapoxetine; pharmacokinetics; premature ejaculation

Indexed keywords

DAPOXETINE; DAPOXETINE N OXIDE; DESMETHYLDAPOXETINE; DIDESMETHYLDAPOXETINE; SEROTONIN UPTAKE INHIBITOR; UNCLASSIFIED DRUG;

ABDOMINAL DISCOMFORT; ADULT; AREA UNDER THE CURVE; ARTICLE; CAUCASIAN; CHINESE; CLINICAL ASSESSMENT; CLINICAL TRIAL; COLD SWEAT; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIARRHEA; DIZZINESS; DRUG ABSORPTION; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DOSE INCREASE; DRUG ELIMINATION; DRUG EXCRETION; DRUG FATALITY; DRUG HALF LIFE; DRUG INDUCED HEADACHE; DRUG METABOLISM; DRUG TOLERABILITY; DRUG URINE LEVEL; DRUG WITHDRAWAL; ECG ABNORMALITY; ETHNIC GROUP; FATIGUE; FEELING ABNORMAL; FEVER; FLATULENCE; HEART ARRHYTHMIA; HEART PALPITATION; HOT FLUSH; HUMAN; HYPERTENSION; JAPANESE; MALE; MAXIMUM PLASMA CONCENTRATION; METABOLITE; MULTICENTER STUDY; MULTIPLE DRUG DOSE; MUSCLE TIGHTNESS; NAUSEA; NORMAL HUMAN; PHARMACOLOGICAL PARAMETERS; RANDOMIZED CONTROLLED TRIAL; RESTLESSNESS; SHOULDER PAIN; SIDE EFFECT; SINGLE DRUG DOSE; SOMNOLENCE; SORE THROAT; THORAX PAIN; TIME TO MAXIMUM PLASMA CONCENTRATION; TONSILLITIS; ULCERATIVE COLITIS; UPPER ABDOMINAL PAIN; UPPER RESPIRATORY TRACT INFECTION; VITAL SIGN;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; BENZYLAMINES; CHINA; CROSS-OVER STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; EUROPEAN CONTINENTAL ANCESTRY GROUP; GREAT BRITAIN; HALF-LIFE; HUMANS; JAPAN; MALE; METABOLIC CLEARANCE RATE; MIDDLE AGED; NAPHTHALENES; SEROTONIN UPTAKE INHIBITORS; UNITED STATES; YOUNG ADULT;

EID: 77953648907     PISSN: 00912700     EISSN: 15524604     Source Type: Journal    
DOI: 10.1177/0091270009359183     Document Type: Article

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