Evaluation of the antioxidant properties and effects on the biotransformation of commercial herbal preparations using rat liver endoplasmic reticulum;Evaluación de la actividad antioxidante y los efectos sobre biotransformación de productos herbales comerciales en retículo endoplásmico hepático de rata

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas

Volumn 8, Issue 2, 2009, Pages 110-120

  Letelier, Maria E ^a   Cortes, Juan F ^a   Lepe, Ana M ^a   Jara, José A ^a   Molina Berríos, Alfredo ^a   Rodriguez, Carmen ^a   Iturra Montecinos, Pablo ^a   Faúndez, Mario ^b  

^a UNIVERSITY OF CHILE   (Chile)

^b PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

Author keywords

Biotransformation enzymes; Herbal antioxidants; Herbal ingredient biotransformation; Microsomes; Oxidative stress; Polyphenols

Indexed keywords

ALCOHOL; ASCORBIC ACID; AVENA SATIVA EXTRACT; CARDUS MARIANUS T.M.; CRATAEGUS EXTRACT; CRATAEGUS OXYACANTHA EXTRACT; CYTOCHROME P450; ENZYME; FERRIC ION; FOENICULUM VULGARE EXTRACT; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; HERBACEOUS AGENT; LIPID; MELINERV; MELISSA OFFICINALIS EXTRACT; N DEMETHYLASE; NATURPEP C; OPUNTIA EXTRACT; OPUNTIA FICUS INDICA EXTRACT; PASSIKIT; PEUMUS BOLDUS EXTRACT; PLANT EXTRACT; SENNA EXTRACT; SILYBUM MARIANUM EXTRACT; THIOL; TILIA CORDATA EXTRACT; TRIQUE COMPUESTO; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE; VALERIAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; CRATAEGUS; CRATAEGUS OXYACANTHA; DRUG TRANSFORMATION; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; FENNEL; LIPID PEROXIDATION; LIPOPHILICITY; LIVER; MALE; MELISSA OFFICINALIS; MICROSOME; NONHUMAN; OAT; OPUNTIA; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PASSION FRUIT; PEUMUS BOLDUS; RAT; SENNA; SILYBUM MARIANUM; TILIA CORDATA; TILIACEAE; VALERIANA OFFICINALIS;

ANIMALIA; AVENA SATIVA; CASSIA SENNA; CRATAEGUS MONOGYNA; FOENICULUM VULGARE; MELISSA OFFICINALIS; OPUNTIA FICUS-INDICA; PASSIFLORA INCARNATA; PEUMUS BOLDUS; RATTUS; SILYBUM MARIANUM; TILIA CORDATA; VALERIANA OFFICINALIS;

EID: 77953648173     PISSN: None     EISSN: 07177917     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Alterman MA, Marekushev SA, Levchenko LA, Raevskii AV, Devichenskii VM. 1981. Cytochrome P450 distribution in endoplasmic reticulum membranes of rat liver. Biokhimiia 46(2):222-229.
2. Aniya Y, Shimaji M, Naito A. 1993. Increase in liver microsomal glutathione S-transferase activity by phenobarbital treatment of rats. Possible involvement of oxidative activation via cytochrome P450. Biochem Pharmacol 46, 1741-1747.
3. Dröge W. 2002. Free radicals in the physiological control of cell function. Physiol Rev 82(1):47-95.
4. Du Y, Guo G, Lou H. 2007. Grape seed polyphenols protect cardiac cells from apoptosis via induction of endogenous antioxidant enzymes. J Agric Food Chem 55(5):1695-1701.
5. rd edn). Claredon Press, Oxford.
6. Healy FG, Krasnoff SB, Wach, M, Gibson DM, Loria R. 2002. Involvement of a cytochrome P450 monooxygenase in Thaxtomin A. biosynthesis by Streptomyces acidiscabies. J Bacteriol 184(7):2019-2029.
7. Lee H, Yang L, Wang Ch, Hu S, Chang H, Lee Y. 2003. Differential effects of natural polyphenols on neuronal survival in primary cultured central neurons against glutamate and glucose deprivation-induced neuronal death. Brain Res 986:103-113.
8. Leone M, Zhai D, Sareth S, Kitada S, Reed JC, Pellecchia M 2003. Cancer prevention by Tea polyphenols is linked to their direct inhibition of antiapoptotic Bcl-2 family proteins. Cancer Res 63:8118-8121.
9. Letelier ME, Del Villar, E., Sánchez E. 1985. Drug tolerance and detoxicating enzymes in Octodon degus and Wistar rats. A comparative study. Comp Biochem Physiol 80(1):195-198.
10. Letelier M.E, Martínez M, Gonzalez-Lira V, Faúndez M, Aracena-Parks P. 2006. Inhibition of cytosolic Glutathione s-transferase activity from rat liver by copper. Chem Biol Interact 164:39-48.
11. Letelier ME, Molina-Berríos A, Cortés-Troncoso J, Jara Sandoval J, Holst M, Palma K, Montoya M, Miranda D, González-Lira V. 2008. DPPH and oxygen free radicals 22:279-286.
12. Letelier ME, Pimentel A, Pino P, Lepe AM, Faúndez M, Aracena P, Speisky H. 2005. Microsomal UDP-Glucuronyltransferase in rat liver: Oxidative activation. Basic Clin Pharmacol Toxicol 96:480-486.
13. Lowry OH, Rosenbrough NJ, Farr AL, Randall RJ. 1951. Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-273.
14. Middleton E, Kandaswami C, Theoharides T. 2000. The effects of plants flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer. Pharmacol Rev 52:673-751.
15. Omura T, Sato R. 1964. The carbon monoxide-binding pigment of liver microsomes. II. Solubilization, purification, and properties. J Biol Chem 239(7):2370-2378.
16. Siess MH, LeBon AM, Suschetet M. 1992. Dietary modification of drug-metabolizing enzyme activities: Dose-response effect of flavonoids. J Toxicol Environ Health 35:141-152.
17. Urquiaga I, Leighton F. 2000. Plant polyphenol antioxidants and oxidative stress. Biol Res 33(2):55-64.
18. Wang TS, Lii CK, Chang JY, Kuo CI, Chen HP. 2007. Anti-Fenton reaction activity of three taxa of water yam (Dioscorea alata L.). Int J Food Sci Tech 42(9):1107-1113.