메뉴 건너뛰기




Volumn 1, Issue 1, 2010, Pages

Linking calorie restriction to longevity through sirtuins and autophagy: Any role for TOR

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; SIRTUIN 1; TARGET OF RAPAMYCIN KINASE; SIRTUIN;

EID: 77953624320     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2009.17     Document Type: Article
Times cited : (51)

References (21)
  • 1
    • 74849115774 scopus 로고    scopus 로고
    • MTOR-driven aging: Speeding car without brakes
    • Blagosklonny MV. mTOR-driven aging: speeding car without brakes. Cell Cycle 2009; 8: 4055-4059.
    • (2009) Cell Cycle , vol.8 , pp. 4055-4059
    • Blagosklonny, M.V.1
  • 2
    • 22744452215 scopus 로고    scopus 로고
    • Food restriction, evolution and ageing
    • DOI 10.1016/j.mad.2005.03.021, PII S0047637405000898
    • Kirkwood TB, Shanley DP. Food restriction, evolution and ageing. Mech Ageing Dev 2005; 126: 1011-1016. (Pubitemid 41033182)
    • (2005) Mechanisms of Ageing and Development , vol.126 , Issue.SPEC. ISS. 9 , pp. 1011-1016
    • Kirkwood, T.B.L.1    Shanley, D.P.2
  • 3
    • 0034626747 scopus 로고    scopus 로고
    • Genetic pathways that regulate ageing in model organisms
    • Guarente L, Kenyon C. Genetic pathways that regulate ageing in model organisms. Nature 2000; 408: 255-262.
    • (2000) Nature , vol.408 , pp. 255-262
    • Guarente, L.1    Kenyon, C.2
  • 4
    • 3042648746 scopus 로고    scopus 로고
    • Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway
    • DOI 10.1016/j.cub.2004.03.059, PII S0960982204002386
    • Kapahi P, Zid BM, Harper T, Koslover D, Sapin V, Benzer S. Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway. Curr Biol 2004; 14: 885-890. (Pubitemid 38800910)
    • (2004) Current Biology , vol.14 , Issue.10 , pp. 885-890
    • Kapahi, P.1    Zid, B.M.2    Harper, T.3    Koslover, D.4    Sapin, V.5    Benzer, S.6
  • 7
    • 3943071801 scopus 로고    scopus 로고
    • Sirtuin activators mimic caloric restriction and delay ageing in metazoans
    • DOI 10.1038/nature02789
    • Wood JG, Rogina B, Lavu S, Howitz K, Helfand SL, Tatar M et al. Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature 2004; 430: 686-689. (Pubitemid 39061685)
    • (2004) Nature , vol.430 , Issue.7000 , pp. 686-689
    • Wood, J.G.1    Regina, B.2    Lavu, S.3    Hewitz, K.4    Helfand, S.L.5    Tatar, M.6    Sinclair, D.7
  • 8
    • 32044465506 scopus 로고    scopus 로고
    • TOR signaling in growth and metabolism
    • DOI 10.1016/j.cell.2006.01.016, PII S0092867406001085
    • Wullschleger S, Loewith R, Hall MN. TOR signaling in growth and metabolism. Cell 2006; 124: 471-484. (Pubitemid 43199434)
    • (2006) Cell , vol.124 , Issue.3 , pp. 471-484
    • Wullschleger, S.1    Loewith, R.2    Hall, M.N.3
  • 9
    • 77953577017 scopus 로고    scopus 로고
    • MTORs role in ageing: Protein synthesis or autophagy?
    • Hands SL, Proud CG, Wyttenbach A. mTORs role in ageing: protein synthesis or autophagy? Aging 2009; 1: 586-597.
    • (2009) Aging , vol.1 , pp. 586-597
    • Hands, S.L.1    Proud, C.G.2    Wyttenbach, A.3
  • 10
    • 67649347537 scopus 로고    scopus 로고
    • Growth and aging: A common molecular mechanism
    • Blagosklonny MV, Hall MN. Growth and aging: a common molecular mechanism. Aging 2009; 1: 357-362.
    • (2009) Aging , vol.1 , pp. 357-362
    • Blagosklonny, M.V.1    Hall, M.N.2
  • 11
    • 33750029285 scopus 로고    scopus 로고
    • Aging and immortality: Quasi-programmed senescence and its pharmacologic inhibition
    • Blagosklonny MV. Aging and immortality: quasi-programmed senescence and its pharmacologic inhibition. Cell Cycle 2006; 5: 2087-2102. (Pubitemid 44566240)
    • (2006) Cell Cycle , vol.5 , Issue.18 , pp. 2087-2102
    • Blagosklonny, M.V.1
  • 13
    • 67650944993 scopus 로고    scopus 로고
    • Rapamycin fed late in life extends lifespan in genetically heterogenous mice
    • Harrison DE, Strong R, Sharp ZD, Nelson JF, Astle CM, Flurkey K et al. Rapamycin fed late in life extends lifespan in genetically heterogenous mice. Nature 2009; 460: 392-396.
    • (2009) Nature , vol.460 , pp. 392-396
    • Harrison, D.E.1    Strong, R.2    Sharp, Z.D.3    Nelson, J.F.4    Astle, C.M.5    Flurkey, K.6
  • 14
    • 35648995939 scopus 로고    scopus 로고
    • MSN2 and MSN4 link calorie restriction and TOR to Sirtuin-mediated lifespan extension in Saccharomyces cerevisiae
    • Medvedik O, Lamming DW, Kim KD, Sinclair DA. MSN2 and MSN4 link calorie restriction and TOR to Sirtuin-mediated lifespan extension in Saccharomyces cerevisiae. PLoS Biol 2007; 5: e261.
    • (2007) PLoS Biol , vol.5
    • Medvedik, O.1    Lamming, D.W.2    Kim, K.D.3    Sinclair, D.A.4
  • 15
    • 67649369072 scopus 로고    scopus 로고
    • At concentrations that inhibit mTOR, resveratrol suppresses cellular senescence
    • Demidenko ZN, Blagosklonny MV. At concentrations that inhibit mTOR, resveratrol suppresses cellular senescence. Cell Cycle 2009; 8: 1901-1904.
    • (2009) Cell Cycle , vol.8 , pp. 1901-1904
    • Demidenko, Z.N.1    Blagosklonny, M.V.2
  • 18
    • 41149159767 scopus 로고    scopus 로고
    • Rapamycin inhibits polyglutamine aggregation independently of autophagy by reducing protein synthesis
    • DOI 10.1124/mol.107.043398
    • King MA, Hands S, Hafiz F, Mizushima N, Tolkovsky AM, Wyttenbach A. Rapamycin inhibits polyglutamine aggregation independently of autophagy by reducing protein synthesis. Mol Pharmacol 2008; 73: 1052-1063. (Pubitemid 351439187)
    • (2008) Molecular Pharmacology , vol.73 , Issue.4 , pp. 1052-1063
    • King, M.A.1    Hands, S.2    Hafiz, F.3    Mizushima, N.4    Tolkovsky, A.M.5    Wyttenbach, A.6
  • 19
    • 40149105890 scopus 로고    scopus 로고
    • A role for autophagy in the extension of lifespan by dietary restriction in C. elegans
    • Hansen M, Chandra A, Mitic LL, Onken B, Driscoll M, Kenyon C. A role for autophagy in the extension of lifespan by dietary restriction in C. elegans. PLoS Genet 2008; 4: e24.
    • (2008) PLoS Genet , vol.4
    • Hansen, M.1    Chandra, A.2    Mitic, L.L.3    Onken, B.4    Driscoll, M.5    Kenyon, C.6
  • 20
    • 34548265278 scopus 로고    scopus 로고
    • Autophagy and human disease
    • Huang J, Klionsky DJ. Autophagy and human disease. Cell Cycle 2007; 6: 1837-1849. (Pubitemid 47327901)
    • (2007) Cell Cycle , vol.6 , Issue.15 , pp. 1837-1849
    • Huang, J.1    Klionsky, D.J.2
  • 21
    • 74549205329 scopus 로고    scopus 로고
    • Validation of anti-aging drugs by treating age-related diseases
    • Blagosklonny MV. Validation of anti-aging drugs by treating age-related diseases. Aging 2009; 1: 281-288.
    • (2009) Aging , vol.1 , pp. 281-288
    • Blagosklonny, M.V.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.