Moderate hypoglycemia is associated with vasospasm, cerebral infarction, and 3-month disability after subarachnoid hemorrhage

Neurocritical Care

Volumn 12, Issue 2, 2010, Pages 181-187

  Naidech, Andrew M ^a   Levasseur, Kimberly ^a   Liebling, Storm ^a   Garg, Rajeev K ^b   Shapiro, Michael ^c   Ault, Michael L ^d   Afifi, Sherif ^d   Batjer, H Hunt ^c  

^a NORTHWESTERN UNIVERSITY   (United States)

^b NORTHWESTERN MEMORIAL HOSPITAL   (United States)

^c Department of Surgery ^*  (United States)

^d UNIVERSITY OF CHICAGO MEDICAL CENTER   (United States)

Author keywords

Glucose; Insulin; Outcomes; Subarachnoid hemorrhage

Indexed keywords

DEXAMETHASONE; GLUCOSE; NIMODIPINE; PRAVASTATIN;

ADULT; ANGIOGRAPHY; ARTICLE; BRAIN INFARCTION; BRAIN INJURY; BRAIN VASOSPASM; DIABETES MELLITUS; DISEASE SEVERITY; FEMALE; HOSPITAL ADMISSION; HUMAN; HYPOGLYCEMIA; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PHYSICAL DISABILITY; PRIORITY JOURNAL; RADIOGRAPHY; SUBARACHNOID HEMORRHAGE;

CEREBRAL INFARCTION; DISABILITY EVALUATION; FEMALE; HOSPITALIZATION; HUMANS; HYPOGLYCEMIA; LENGTH OF STAY; MALE; MIDDLE AGED; PREVALENCE; PROSPECTIVE STUDIES; RETROSPECTIVE STUDIES; SUBARACHNOID HEMORRHAGE; TIME FACTORS; TOMOGRAPHY, X-RAY COMPUTED; VASOSPASM, INTRACRANIAL;

EID: 77953617115     PISSN: 15416933     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12028-009-9311-z     Document Type: Article

References (26)

1. Badjatia N, Topcuoglu MA, Buonanno FS, Smith EE, Nogueira RG, Rordorf GA, et al. Relationship between hyperglycemia and symptomatic vasospasm after subarachnoid hemorrhage. Crit Care Med. 2005;33:1603-9.
2. Frontera JA, Fernandez A, Claassen J, Schmidt M, Schumacher HC, Wartenberg K, et al. Hyperglycemia after SAH: predictors, associated complications and impact on outcome. Stroke. 2006; 37:199-203.
3. Kruyt ND, Biessels GJ, de Haan RJ, Vermeulen M, Rinkel GJ, Coert B, Roos YB. Hyperglycemia and clinical outcome in aneurysmal subarachnoid hemorrhage. A meta-analysis. Stroke 2009; Epub ahead of print.
4. Schlenk F, Graetz D, Nagel A, Schmidt M, Sarrafzadeh A. Insulin- related decrease in cerebral glucose despite normoglycemia in aneurysmal subarachnoid hemorrhage. Crit Care. 2008;12:R9.
5. Bell DA, Strong AJ. Glucose/insulin infusions in the treatment of subarachnoid haemorrhage: a feasibility study. Br J Neurosurg. 2005;19:21-4.
6. Bilotta F, Spinelli A, Giovannini F, Doronzio A, Delfini R, Rosa G. The effect of intensive insulin therapy on infection rate, vasospasm, neurologic outcome, and mortality in neurointensive care unit after intracranial aneurysm clipping in patients with acute subarachnoid hemorrhage: a randomized prospective pilot trial. J Neurosurg Anesthesiol. 2007;19:156-60.
7. Latorre JG, Chou SH, Nogueira RG, Singhal AB, Carter BS, Ogilvy CS, et al. Effective glycemic control with aggressive hyperglycemia management is associated with improved outcome in aneurysmal subarachnoid hemorrhage. Stroke. 2009;40:1644-52.
8. Wiener RS, Wiener DC, Larson RJ. Benefits and risks of tight glucose control in critically ill adults: A meta-analysis. JAMA. 2008;300:933-44.
9. Thiele RH, Pouratian N, Zuo Z, Scalzo DC, Dobba HA, Dumont AS, et al. Strict glucose control does not affect mortality after aneurysmal subarachnoid hemorrhage. Anesthesiology. 2009;110: 603-10.
10. The Nice-Sugar Study Investigators. Intensive versus conventional glucose control in critically patients. New Engl J Med 2009;360:1283-97.
11. Ali NA, O'Brien JMJ, Dungan K, Phillips G, Marsh CB, Lemeshow S, et al. Glucose variability and mortality in patients with sepsis. Crit Care Med. 2008;36:2316-21.
12. Egi M, Bellomo R, Stachowski E, French C, Hart G. Variability of blood glucose concentration and short-term mortality in critically ill patients. Anesthesiology. 2006;105:244-52.
13. Schlenk F, Vajkoczy P, Sarrafzadeh A. Inpatient hyperglycemia following aneurysmal subarachnoid hemorrhage: Relation to cerebral metabolism and outcome. Neurocrit Care 2009; Epub ahead of print.
14. Schlenk F, Nagel A, Graetz D, Sarrafzadeh A. Hyperglycemia and cerebral glucose in aneurysmal subarachnoid hemorrhage. Intensive Care Med. 2008;34:1200-7.
15. Vespa P, Boonyaputthikul R, McArthur DL, Miller C, Etchepare M, Bergsneider M, et al. Intensive insulin therapy reduces microdialysis glucose values without altering glucose utilization or improving the lactate/pyruvate ratio after traumatic brain injury. Crit Care Med. 2006;34:850-6.
16. Classen J, Vu A, Kreiter KT, Kowalski RG, Du EY, Ostapkovich N, et al. Effect of acute physiologic derangements on outcome after subarachnoid hemorrhage. Crit Care Med. 2004;32:832-8.
17. Tseng M-Y, Czosnyka M, Richards H, Pickard JD, Kirkpatrick PJ. Effects of acute treatment with pravastatin on cerebral vasospasm, autoregulation, and delayed ischemic deficits after aneurysmal subarachnoid hemorrhage: a phase 2 randomized placebo-controlled trial. Stroke. 2005;36:1627-32.
18. Sen J, Belli A, Albon H, Morgan L, Petzold A, Kitchen N. Triple-h therapy in the management of aneurysmal subarachnoid haemorrhage. Lancet Neurol. 2003;2:614-21.
19. Naidech A, Jovanovic B, Wartenberg K, Parra A, Ostapkovich N, Connolly E, et al. Higher hemoglobin is associated with improved outcome after subarachnoid hemorrhage. Crit Care Med. 2008; 35:2383-9.
20. Rabinstein AA, Weigand S, Atkinson JLD, Wijdicks EFM. Patterns of cerebral infarction in aneurysmal subarachnoid hemorrhage. Stroke. 2005;36:992-7.
21. Banks J, Marotta C. Outcomes validity and reliability of the modified Rankin scale: implications for stroke clinical trials: a literature review and synthesis. Stroke. 2007;38:1091-6.
22. Wilson JTL, Hareendran A, Grant M, Baird T, Schulz UGR, Muir KW, et al. Improving the assess of outcomes in stroke. Use of a structured interview to assign grade on the modified Rankin scale. Stroke. 2002;33:2243-6.
23. Krinsley JS, Grover A. Severe hypoglycemia in critically ill patients: risk factors and outcomes. Crit Care Med. 2007;35: 2262-7.
24. Krinsley JS. Glycemic variability: a strong independent predictor of mortality in critically ill patients. Crit Care Med. 2008;36: 3008-13.
25. Egi M, Bellomo R, Stachowski E, French C, Hart G, Hegarty C, et al. Blood glucose concentration and outcome of critical illness: the impact of diabetes. Crit Care Med. 2008;36:2249-55.
26. Inzucchi SE, Siegel MD. Glucose control in the icu - how tight is tight enough? New Engl J Med. 2009;360:1346-8.