Eugenol restricts DMBA croton oil induced skin carcinogenesis in mice: Downregulation of c-Myc and H-ras, and activation of p53 dependent apoptotic pathway

Journal of Dermatological Science

Volumn 59, Issue 1, 2010, Pages 31-39

  Pal, Debolina ^a   Banerjee, Sarmistha ^a   Mukherjee, Sudeshna ^a   Roy, Anup ^b   Panda, Chinmay K ^a   Das, Sukta ^a  

^a CHITTARANJAN NATIONAL CANCER INSTITUTE   (India)

^b Midnapore Medical College and Hospital   (India)

Author keywords

Apoptosis; Chemoprevention; Croton oil; DMBA; Eugenol; Proliferation

Indexed keywords

CASPASE 3; CROTON OIL; DIMETHYLBENZ[A]ANTHRACENE; EUGENOL; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; 7,12 DIMETHYLBENZ[A]ANTHRACENE; ANTINEOPLASTIC AGENT; BCL2 PROTEIN, MOUSE; ONCOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER SURVIVAL; CELL PROLIFERATION; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DOWN REGULATION; HISTOPATHOLOGY; MALE; MOUSE; NONHUMAN; ONCOGENE C MYC; ONCOGENE H RAS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN CARCINOGENESIS; SKIN TUMOR; TUMOR VOLUME; UPREGULATION; ANIMAL; CELL TRANSFORMATION; CHEMICALLY INDUCED; DRUG EFFECTS; FEMALE; ONCOGENE MYC; ONCOGENE RAS; PATHOLOGY; SKIN NEOPLASMS; TOXICITY; TUMOR SUPPRESSOR GENE;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; ANTICARCINOGENIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CELL TRANSFORMATION, NEOPLASTIC; CROTON OIL; DOWN-REGULATION; EUGENOL; FEMALE; GENES, MYC; GENES, P53; GENES, RAS; MICE; PROTO-ONCOGENE PROTEINS; SKIN NEOPLASMS; UP-REGULATION; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 77953610307     PISSN: 09231811     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2010.04.013     Document Type: Article

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