Immunohistochemical evaluation of inflammatory and proliferative markers in adjacent normal thyroid tissue in patients undergoing total thyroidectomy: Results of a preliminary study

Journal of Experimental and Clinical Cancer Research

Volumn 29, Issue 1, 2010, Pages

  Ardito, Guglielmo ^a   Revelli, Luca ^a   Boninsegna, Alma ^a   Sgambato, Alessandro ^a   Moschella, Francesca ^a   Marzola, Maria Cristina ^b   Giustozzi, Erica ^a   Avenia, Nicola ^a   Castelli, Mauro ^c   Rubello, Domenico ^b  

^a CATHOLIC UNIVERSITY   (Italy)

^b SANTA MARIA DELLA MISERICORDIA HOSPITAL   (Italy)

^c REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CYTOKERATIN 19; GLYCOPROTEIN GP 130; INTERLEUKIN 6 RECEPTOR BETA SUBUNIT; INTERLEUKIN RECEPTOR; PROTEIN P53; STAT3 PROTEIN; UNCLASSIFIED DRUG; STAT3 PROTEIN, HUMAN; TP53 PROTEIN, HUMAN; TUMOR MARKER;

ADENOMA; ARTICLE; CANCER RISK; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; CYTOKINE PRODUCTION; CYTOPLASM; DISEASE DURATION; FEMALE; FOLLICULAR ADENOMA; GRAVES DISEASE; HASHIMOTO DISEASE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; NODULAR GOITER; PAPILLARY CARCINOMA; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; THYROID DISEASE; THYROID GLAND; THYROIDECTOMY; THYROTOXICOSIS; TRANSCRIPTION INITIATION; ADULT; ENZYME IMMUNOASSAY; METABOLISM; MIDDLE AGED; PATHOLOGY; PILOT STUDY; THYROID TUMOR;

ADENOMA; ADULT; CARCINOMA, PAPILLARY; CYTOKINE RECEPTOR GP130; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; KERATIN-19; MIDDLE AGED; PILOT PROJECTS; STAT3 TRANSCRIPTION FACTOR; THYROID NEOPLASMS; THYROIDECTOMY; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53; YOUNG ADULT;

EID: 77953605663     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/1756-9966-29-77     Document Type: Article

References (11)

1. Total thyroidectomy for benign thyroid diseases. CU Friguglietti CS Lin MA Kulcsar, Laryngoscope 2003 113 1820 6 10.1097/00005537-200310000-00030 14520113
2. Anti-tumor immunity and autoimmunity: a balancing act of regulatory T cells. WZ Wei GP Morris YC Kong, Cancer Immunol Immunother 2004 53 73 8 10.1007/s00262-003-0444-1 14610619
3. The cytokine receptor gp130: faithfully promiscuous. G Muller-Newen, SciSTKE 2003 201 E40
4. STAT proteins: from normal control of cellular events to tumorigenesis. V Calo M Migliavacca V Bazan M Macaluso M Buscemi N Gebbia A Russo, J Cell Physiol 2003 197 157 68 10.1002/jcp.10364 14502555
5. Modulation of signal transducer and activator of transcription 3 activities by p53 tumor suppressor in breast cancer cells. J Lin X Jin K Rothman HJ Lin H Tang W Burke, Cancer Res 2002 62 376 80 11809683
6. Interleukin-6 acts as an antiapoptotic factor in human esophageal carcinoma cells through the activation of both STAT3 and mitogenactivated protein kinase pathways. C Leu F Wong C Chang S Huang C Hu, Oncogene 2003 22 7809 18 10.1038/sj.onc.1207084 14586407
7. p53 regulates STAT3 phosphorylation and DNA binding activity in human prostate cancer cells expressing constitutively active STAT3. J Lin H Tang X Jin G Jia JT Hsieh, Oncogene 2002 21 3082 8 10.1038/sj.onc.1205426 12082540
8. Endoplasmic reticulum stress induces p53 cytoplasmic localization and prevents p53-dependent apoptosis by a pathway involving glycogen synthase kinase-3beta. L Qu S Huang D Baltzis AM Rivas-Estilla O Pluquet M Hatzglou C Koumenis Y Taya A Yoshimura AE Koromilas, Genes Dev 2004 26 234 9
9. Distinction between papillary thyroid hyperplasia and papillary thyroid carcinoma by immunohistochemical staining for CK19, galectin-3 and HBME-1. MB Casey CM Lohse RV Lloyd, Endocr Pathol 2003 14 55 60 10.1385/EP:14:1:55 12746563
10. Immunohistochemical analysis of the IL-6 family of cytokines and their receptors in benign, hyperplastic, and malignany human prosatate. M Royuela M Ricote MS Parsons I Garcia-Tunon R Paniagua MP de Miguel, J Pathol 2004 202 41 49 10.1002/path.1476 14694520
11. Cytoplasmic accumulation of p53 protein: an independent prognostic indicator in colorectal adenocarcinomas. S Bosari G Viale P Bossi M Maggioni G Coggi JJ Murray AK Lee, J Natl Cancer Inst 1994 86 681 7 10.1093/jnci/86.9.681 8158699