Stimulation of skin menthol receptors stimulates detrusor activity in conscious rats

Neurourology and Urodynamics

Volumn 29, Issue 3, 2010, Pages 506-511

  Chen, Zhong ^a   Ishizuka, Osamu ^a   Imamura, Tetsuya ^a   Aizawa, Naoki ^a   Kurizaki, Yoshiki ^a   Igawa, Yasuhiko ^a   Nishizawa, Osamu ^a   Andersson, Karl Erik ^b  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Bladder; Detrusor overactivity; Neurogenic bladder; Sprague Dawley rats; TRPM8

Indexed keywords

MENTHOL; TRANSIENT RECEPTOR POTENTIAL CHANNEL M8; TRANSIENT RECEPTOR POTENTIAL CHANNEL M; TRPM8 PROTEIN, RAT;

ANIMAL EXPERIMENT; ARTICLE; BLADDER CAPACITY; CONSCIOUSNESS; CONTROLLED STUDY; CYSTOMETRY; DETRUSOR MUSCLE; FEMALE; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; LEG; MICTURITION; MUSCLE EXCITATION; NONHUMAN; PROTEIN EXPRESSION; RAT; SKIN SENSATION; SKIN STIMULATION; STATISTICAL SIGNIFICANCE; URINARY FREQUENCY; URINE VOLUME; ANIMAL; BIOSYNTHESIS; BLADDER; METABOLISM; PHYSIOLOGY; SKIN; SMOOTH MUSCLE; SPRAGUE DAWLEY RAT; TOPICAL DRUG ADMINISTRATION;

ADMINISTRATION, TOPICAL; ANIMALS; CONSCIOUSNESS; FEMALE; MENTHOL; MUSCLE, SMOOTH; RATS; RATS, SPRAGUE-DAWLEY; SKIN; TRPM CATION CHANNELS; URINARY BLADDER;

EID: 77953598608     PISSN: 07332467     EISSN: 15206777     Source Type: Journal    
DOI: 10.1002/nau.20774     Document Type: Article

References (28)

1. Pedersen SF, Owsianik G, Nilius B. TRP channels: An overview. Cell Calcium 2005;38:233-252
2. Voets T, Nilius B. TRPs make sense. J Membr Biol 2003;192:1-8.
3. McKemy DD, Neuhausser WM, Julius D. Identification of a cold receptor reveals a general role for TRP channels in thermosensation. Nature 2002; 416:52-58
4. Peier AM, Moqrich A, Hergarden AC, et al. A TRP channel that senses cold stimuli and menthol. Cell 2002;108:705-715
5. Tsavaler L, Shapero MH, Morkowski S, et al. Trp-p8, a novel prostate-specific gene, is up-regulated in prostate cancer and other malignancies and shares high homology with transient receptor potential calcium channel proteins. Cancer Res 2001;61:3760-3769
6. Stein RJ, Santos S, Nagatomi J, et al. Cool (TRPM8) and hot (TRPV1) receptors in the bladder and male genital tract. J Urol 2004;172:1175-1178
7. Du S, Araki I, Kobayashi H, et al. Differential expression profile of cold (TRPA1) and cool (TRPM8) receptors in human urogenital organs. Urology 2008;72:450-455
8. Mukerji G, Yiangou Y, Corcoran SL, et al. Cool and menthol receptor TRPM8 in human urinary bladder disorders and clinical correlations. BMC Urol 2006; 6:6.
9. Tsukimi Y, Mizuyachi K, Yamasaki T, et al. Cold response of the bladder in guinea pig: Involvement of transient receptor potential channel, TRPM8. Urology 2005;65:406-410
10. Nomoto Y, Yoshida A, Ikeda S, et al. Effect of menthol on detrusor smoothmuscle contraction and the micturition reflex in rats. Urology 2008;72:701-705
11. Bors EH, Blinn KA. Spinal reflex activity from the vesical mucosa in paraplegic patients. AMA Arch Neurol Psychiatry 1957;78:339-354
12. Lindstrom S, Mazieres L. Effect of menthol on the bladder cooling reflex in the cat. Acta Physiol Scand 1991;141:1-10.
13. Geirsson G. Evidence of cold receptors in the human bladder: Effect of menthol on the bladder cooling reflex. J Urol 1993;150:427-430
14. Imamura T, Ishizuka O, Aizawa N, et al. Cold environmental stress induces detrusor overactivity via resiniferatoxin-sensitive nerves in conscious rats. Neurourol Urodyn 2008;27:348-352
15. Chen Z, Ishizuka O, Imamura T, et al. Role of a1-adrenergic receptors in detrusor overactivity induced by cold stress in conscious rats. Neurourol Urodyn 2009;28:251-256.
16. Eccles R. Menthol and related cooling compounds. J Pharm Pharmacol 1994; 46:618-630
17. Cliff MA, Green BG. Sensory irritation and coolness produced by menthol: Evidence for selective desensitization of irritation. Physiol Behav 1994; 56:1021-1029
18. Green BG. The sensory effects of l-menthol on human skin. Somatosens Mot Res 1992;9:235-244
19. Tajino K, Matsumura K, Kosada K, Shibakusa T, Inoue K, Fushiki T, Hosokawa H, Kobayashi S. 2007. Application of menthol to the skin of whole trunk in mice induces autonomic and behavioral heat-gain responses. Am J Physiol Regul Integr Comp Physiol 293(5):R2128-2135.
20. Cheng CL, Chai CY, De Groat WC. Detrusor-sphincter dyssynergia induced by cold stimulation of the urinary bladder of rats. Am J Physiol 1997;272: R1271-82.
21. Reid G. Thermo TRP channels and cold sensing: What are they really up to? Pflugers Arch 2005;451:250-263
22. Story GM, Peier AM, Reeve AJ, et al. ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures. Cell 2003;112:819-829
23. Schneider T, Hein P, Michel MC. Signal transduction underlying carbacholinduced contraction of rat urinary bladder. I. Phospholipases and Ca2+ sources. J Pharmacol Exp Ther 2004;308:47-53. (Pubitemid 38090698)
24. Geirsson G, Lindstrom S, Fall M. The bladder cooling reflex and the use of cooling as stimulus to the lower urinary tract. J Urol 1999;162: 1890-1896
25. Bidaux G, Roudbaraki M, Merle C, et al. Evidence for specific TRPM8 expression in human prostate secretory epithelial cells: Functional androgen receptor requirement. Endocr Relat Cancer 2005;12:367-382
26. Xu H, Ramsey IS, Kotecha SA, Moran MM, Chong JA, Lawson D, Ge P, Lilly J, Silos-Santiago I, Xie Y, DiStefano PS, Curtis R, Clapham DE. 2002. TRPV3 is a calcium-permeable temperature-sensitive cation channel. Nature 418(6894): 181-186.
27. Zemelman BV, Nesnas N, Lee GA, Miesenbock G. 2003. Photochemical gating of heterologous ion channels: remote control over genetically designated populations of neurons. Proc Natl Acad Sci U S A 100(3):1352-1357.
28. Tsuzuki K, Xing H, Ling J, et al. Menthol-induced Ca2+ release from presynaptic Ca2+ stores potentiates sensory synaptic transmission. J Neurosci 2004;24:762-771