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77953552159
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Ahmad, N.M.1
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5
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36849082987
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Barrow, J. C.; Rittle, K. E.; Ngo, P. L.; Selnick, H. G.; Graham, S. L.; Pitzenberger, S. M.; McGaughey, G. B.; Colussi, D.; Lai, M.-T.; Huang, Q.; Tugusheva, K.; Espeseth, A. S.; Simon, A. J.; Munshi, S. K.; Vacca Jo, P. ChemMedChem 2007, 2, 995
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84987505887
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Seebach, D.; Juaristi, E.; Miller, D. D.; Schickli, C.; Weber, T. Helv. Chim. Acta 1987, 70, 237
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Seebach, D.1
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7
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77953600146
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For reviews on nitrones and their cycloaddition reactions, see
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For reviews on nitrones and their cycloaddition reactions, see
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8
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29144463002
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Eds.; Wiley: New York
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Jones, R. C. F.; Martin, J. N. In Synthetic Applications of 1,3-Dipolar Cycloaddition Chemistry Toward Heterocycles and Natural Products, The Chemistry of Heterocyclic Compounds; Padwa, A.; Pearson, W. H., Eds.; Wiley: New York, 2002; Vol. 59, pp 1 - 81
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9
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65249116227
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2nd ed.; John Wiley & Sons, Inc.: Hoboken, NJ
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Feuer, H. Nitrile Oxides, Nitrones, and Nitronates in Organic Synthesis, 2nd ed.; John Wiley & Sons, Inc.: Hoboken, NJ, 2008.
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Nitrile Oxides, Nitrones, and Nitronates in Organic Synthesis
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Feuer, H.1
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29144485901
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Cardona, F.; Goti, A. Angew. Chem., Int. Ed. 2005, 44, 7832
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Cardona, F.1
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33749350689
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Bonin, M.; Chauveau, A.; Micouin, L. Synlett 2006, 15, 2349
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Bonin, M.1
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Micouin, L.3
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68349099896
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Brandi, A.1
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18
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77953587689
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For a review, see
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For a review, see
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-
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20
-
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0035544070
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Also see recent examples
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Also see recent examples: Heaney, F.; Fenlon, J.; OMahony, C.; McArdle, P.; Cunningham, D. J. Chem. Soc., Perkin Trans. 1 2001, 3382
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Heaney, F.1
Fenlon, J.2
Omahony, C.3
McArdle, P.4
Cunningham, D.5
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22
-
-
77953569560
-
-
See recent example of 1,3-dipolar cycloaddition of imidazolone nitrones
-
See recent example of 1,3-dipolar cycloaddition of imidazolone nitrones
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-
-
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23
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33847003997
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Cheng, S.; Wu, H.; Hu, X. Synth. Commun. 2007, 37, 297
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43849108597
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Aouadi, K.; Jeanneau, E.; Msaddek, M.; Praly, J.-P. Tetrahedron: Asymmetry 2008, 19, 1145
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Aouadi, K.1
Jeanneau, E.2
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Praly, J.-P.4
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25
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36448961252
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Aouadi, K.; Jeanneau, E.; Msaddek, M.; Praly, J.-P. Synthesis 2007, 21, 3399
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Aouadi, K.1
Jeanneau, E.2
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Praly, J.-P.4
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33845603978
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Aouadi, K.; Vidal, S.; Msaddek, M.; Praly, J.-P. Synlett 2006, 19, 3299
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Aouadi, K.1
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33746969869
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Pernet-Poil-Chevrier, A.; Cantagrel, F.; Le Jeune, K.; Philouze, C.; Chavant, P. Y. Tetrahedron: Asymmetry 2006, 17, 1969
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Pernet-Poil-Chevrier, A.1
Cantagrel, F.2
Le Jeune, K.3
Philouze, C.4
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22144442445
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Cantagrel, F.; Pinet, S.; Gimbert, Y.; Chavant, P. Y. Eur. J. Org. Chem. 2005, 70, 2694
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Cantagrel, F.1
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Chavant, P.Y.4
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33746969869
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Pernet-Poil-Chevrier, A.; Cantagrel, F.; Jeune, K. L.; Philouze, C.; Chavant, P. Y. Tetrahedron: Asymmetry 2006, 17, 1969
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Pernet-Poil-Chevrier, A.1
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Philouze, C.4
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0035799866
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Westermann, B.; Walter, A.; Florke, U.; Altenbach, H.-J. Org. Lett. 2001, 3, 1375
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Westermann, B.1
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Altenbach, H.-J.4
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32
-
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77953608675
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-
The sterochemistry of 10 was confirmed by NOESY. Also see ref 7 a
-
The sterochemistry of 10 was confirmed by NOESY. Also see ref 7 a.
-
-
-
-
33
-
-
77953585198
-
-
Possible mechanism to form 14
-
Possible mechanism to form 14
-
-
-
-
34
-
-
77953598234
-
-
note
-
3COOH, etc.) also work in these reactions. However, these combinations have not been optimized.
-
-
-
-
35
-
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77953606913
-
-
Possible mechanism to 5K
-
Possible mechanism to 5K
-
-
-
-
36
-
-
77953550140
-
-
For other isolated acylaziridines, please see ref 6a and the references cited therein
-
For other isolated acylaziridines, please see ref 6a and the references cited therein.
-
-
-
-
37
-
-
77953557222
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For reviews on reactions of aziridines, see
-
For reviews on reactions of aziridines, see
-
-
-
-
38
-
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1542439649
-
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Eds.; Pergamon: Oxford, UK,; Vol. 6, Chapter
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Mitunobu, O.. In Comprehensive Organic Synthesis; Trost, B. M.; Fleming, I., Eds.; Pergamon: Oxford, UK, 1991; Vol. 6, Chapter 1.3.
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Comprehensive Organic Synthesis
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Mitunobu, O.1
Trost, B.M.2
Fleming, I.3
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39
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0002438786
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Eds.; Pergamon: Oxford, UK,; Vol. 4, Chapter
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Padwa, A. In Comprehensive Organic Synthesis; Trost, B. M.; Fleming, I., Eds.; Pergamon: Oxford, UK, 1991; Vol. 4, Chapter 4.9.
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Comprehensive Organic Synthesis
, pp. 49
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Padwa, A.1
Trost, B.M.2
Fleming, I.3
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40
-
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0009537419
-
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Eds.; Pergamon: Oxford, UK,; Vol. 3, Chapter
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Thompson, D. J. In Comprehensive Organic Synthesis; Trost, B. M.; Fleming, I., Eds.; Pergamon: Oxford, UK, 1991; Vol. 3, Chapter 4.1.
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Comprehensive Organic Synthesis
, pp. 41
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Thompson, D.J.1
Trost, B.M.2
Fleming, I.3
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41
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0003065849
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Eds.; Pergamon: Oxford, UK,; Vol. 5, Chapter
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Hudlicky, T.; Reed, J. W. In Comprehensive Organic Synthesis; Trost, B. M.; Fleming, I., Eds.; Pergamon: Oxford, UK, 1991; Vol. 5, Chapter 8.1.
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Comprehensive Organic Synthesis
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Hudlicky, T.1
Reed, J.W.2
Trost, B.M.3
Fleming, I.4
-
43
-
-
77953565196
-
-
note
-
After silica gel chromatograpgy, there is a minor side product (18) isolated (<5%) for entry 2. The Z -isomer has been comfirmed by COSY and J-resolved HMBC data. This type of side product has been found from other substrates as well.
-
-
-
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44
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33846930164
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Inamoto, K.; Katsuno, M.; Yoshino, T.; Arai, Y.; Hiroya, K.; Sakamoto, T. Tetrahedron 2007, 63, 2695
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Tetrahedron
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Inamoto, K.1
Katsuno, M.2
Yoshino, T.3
Arai, Y.4
Hiroya, K.5
Sakamoto, T.6
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45
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13644254491
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references cited therein
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Xin, L.; Bausch, C. C.; Johnson, J. S. J. Am. Chem. Soc. 2005, 127, 1833 and references cited therein
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Xin, L.1
Bausch, C.C.2
Johnson, J.S.3
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1542375011
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Mattson, A. E.; Bharadwaj, A. R.; Scheidt, K. A. J. Am. Chem. Soc. 2004, 126, 2314
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Mattson, A.E.1
Bharadwaj, A.R.2
Scheidt, K.A.3
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