Patterns and Predictors of Vaginal Bleeding in the First Trimester of Pregnancy

Annals of Epidemiology

Volumn 20, Issue 7, 2010, Pages 524-531

  Hasan, Reem ^a,b   Baird, Donna D ^a   Herring, Amy H ^b,c   Olshan, Andrew F ^b,c   Jonsson Funk, Michele L ^b   Hartmann, Katherine E ^d,e  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b University of North Carolina at Chapel Hill   (United States)

^c UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL   (United States)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Miscarriage; Vaginal Bleeding

Indexed keywords

ADULT; ARTICLE; CLINICAL ASSESSMENT; FEMALE; FETUS ECHOGRAPHY; FIRST TRIMESTER PREGNANCY; GESTATION PERIOD; HUMAN; MAJOR CLINICAL STUDY; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; PLACENTA DISORDER; PREDICTOR VARIABLE; PRIORITY JOURNAL; SPONTANEOUS ABORTION; UTERUS MYOMA; VAGINA BLEEDING; ABORTION, SPONTANEOUS; ADOLESCENT; AGE; COMPLICATION; CONFIDENCE INTERVAL; EDUCATIONAL STATUS; LEIOMYOMA; MIDDLE AGED; PREGNANCY; PREVALENCE; PROSPECTIVE STUDY; RISK; SEVERITY OF ILLNESS INDEX; SOCIOECONOMICS; STATISTICAL MODEL; UNITED STATES; UTERINE HEMORRHAGE; YOUNG ADULT;

ABORTION, SPONTANEOUS; ADOLESCENT; ADULT; AGE FACTORS; CONFIDENCE INTERVALS; EDUCATIONAL STATUS; FEMALE; HUMANS; LEIOMYOMA; LOGISTIC MODELS; MIDDLE AGED; ODDS RATIO; PREGNANCY; PREGNANCY TRIMESTER, FIRST; PREVALENCE; PROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; SOCIOECONOMIC FACTORS; UNITED STATES; UTERINE HEMORRHAGE; YOUNG ADULT;

EID: 77953580278     PISSN: 10472797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.annepidem.2010.02.006     Document Type: Article

References (21)

1. Ananth C.V., Savitz D.A. Vaginal bleeding and adverse reproductive outcomes: A meta-analysis. Paediatr Perinat Epidemiol 1994, 8:62-78.
2. Williams M.A., Mittendorf R., Lieberman E., Monson R.R. Adverse infant outcomes associated with first-trimester vaginal bleeding. Obstet Gynecol 1991, 78:14-18.
3. Berkowitz G.S., Harlap S., Beck G.J., Freeman D.H., Baras M. Early gestational bleeding and pregnancy outcome: A multivariable analysis. Int J Epidemiol 1983, 12:165-173.
4. Weiss J.L., Malone F.D., Vidaver J., Ball R.H., Nyberg D.A., Comstock C.H., et al. Threatened abortion: A risk factor for poor pregnancy outcome, a population-based screening study. Am J Obstet Gynecol 2004, 190:745-750.
5. Yang J., Savitz D.A., Dole N., Hartmann K.E., Herring A.H., Olshan A.F., et al. Predictors of vaginal bleeding during the first two trimesters of pregnancy. Paediatr Perinat Epidemiol 2005, 19:276-283.
6. Batzofin J.H., Fielding W.L., Friedman E.A. Effect of vaginal bleeding in early pregnancy on outcome. Obstet Gynecol 1984, 63:515-518.
7. Sipila P., Hartikainen-Sorri A.L., Oja H., Von Wendt L. Perinatal outcome of pregnancies complicated by vaginal bleeding. Br J Obstet Gynaecol 1992, 99:959-963.
8. Axelsen S.M., Henriksen T.B., Hedegaard M., Secher N.J. Characteristics of vaginal bleeding during pregnancy. Eur J Obstet Gynecol Reprod Biol 1995, 63:131-134.
9. French J.I., McGregor J.A., Draper D., Parker R., McFee J. Gestational bleeding, bacterial vaginosis, and common reproductive tract infections: Risk for preterm birth and benefit of treatment. Obstet Gynecol 1999, 93:715-724.
10. Harville E.W., Wilcox A.J., Baird D.D., Weinberg C.R. Vaginal bleeding in very early pregnancy. Hum Reprod 2003, 18:1944-1947.
11. Laughlin S.K., Baird D.D., Savitz D.A., Herring A.H., Hartmann K.E. Prevalence of uterine leiomyomas in the first trimester of pregnancy: An ultrasound screening study. Obstet Gynecol 2009, 113(3):630-635.
12. Royston P. Multiple imputation of missing values: Update. Stata J 2005, 5:188-201.
13. Hasan R., Baird D.D., Herring A.H., Olshan A.F., Jonsson Funk M.L., Hartmann K.E. Association between first-trimester vaginal bleeding and miscarriage. Obstet Gynecol 2009, 114:860-867.
14. Gomez R., Romero R., Nien J.K., Medina L., Carstens M., Kim Y.M., et al. Idiopathic vaginal bleeding during pregnancy as the only clinical manifestation of intrauterine infection. J Matern Fetal Neonatal Med 2005, 18:31-37.
15. Williams M.A., Hickok D.E., Zingheim R.W., Mittendorf R., Kimelman J., Mahony B.S. Low birth weight and preterm delivery in relation to early-gestation vaginal bleeding and elevated maternal serum alpha-fetoprotein. Obstet Gynecol 1992, 80:745-749.
16. Csapo A.I., Pulkkinen M. Indispensability of the human corpus luteum in the maintenance of early pregnancy. Luteectomy evidence. Obstet Gynecol Surv 1978, 33:69-81.
17. Jauniaux E., Johns J., Burton G.J. The role of ultrasound imaging in diagnosing and investigating early pregnancy failure. Ultrasound Obstet Gynecol 2005, 25:613-624.
18. Jauniaux E., Poston L., Burton G.J. Placental-related diseases of pregnancy: Involvement of oxidative stress and implications in human evolution. Hum Reprod Update 2006, 12:747-755.
19. Gjessing H.K., Skjaerven R., Wilcox A.J. Errors in gestational age: Evidence of bleeding early in pregnancy. Am J Public Health 1999, 89:213-218.
20. Hoffman C.S., Messer L.C., Mendola P., Savitz D.A., Herring A.H., Hartmann K.E. Comparison of gestational age at birth based on last menstrual period and ultrasound during the first trimester. Paediatr Perinatal Epidemiol 2008, 22(6):587-596.
21. Hasan R., Jonsson Funk M.L., Herring A.H., Olshan A.F., Hartmann K.E., Baird D.D. Accuracy of reporting bleeding during pregnancy. Paediatr Perinat Epidemiol 2010, 24:31-34.