An anti-apoptotic pattern correlates with multidrug resistance in acute myeloid leukemia patients: A comparative study of active caspase-3, cleaved PARPs, Bcl-2, Survivin and MDR1 gene

Hematology

Volumn 15, Issue 3, 2010, Pages 135-143

  Guenova, Margarita L ^a   Balatzenko, Gueorgui N ^a   Nikolova, Vessela R ^a   Spassov, Branimir V ^a   Konstantinov, Spiro M ^b  

^a National Specialised Hospital for Active Treatment of Haematological Diseases   (Bulgaria)

^b MEDICAL UNIVERSITY OF SOFIA   (Bulgaria)

Author keywords

Active caspase 3; Acute myeloid leukemia; Apoptosis; Bcl 2; Cleaved PARP; MDR1 gene; Multidrug resistance; Survivin

Indexed keywords

CASPASE 3; COMPLEMENTARY DNA; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL 2; SURVIVIN; ABCB1 PROTEIN, HUMAN; BIRC5 PROTEIN, HUMAN; INHIBITOR OF APOPTOSIS PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; MULTIDRUG RESISTANCE PROTEIN;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; AGED; APOPTOSIS; ARTICLE; CLINICAL ARTICLE; COMPARATIVE STUDY; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; GENE OVEREXPRESSION; HUMAN; IMMUNOPHENOTYPING; MALE; MOLECULAR INTERACTION; MULTIDRUG RESISTANCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; DRUG RESISTANCE; GENE EXPRESSION REGULATION; GENETICS; LEUKEMIA, MYELOID, ACUTE; METABOLISM; MIDDLE AGED; PATHOLOGY;

ADULT; AGED; APOPTOSIS; CASPASE 3; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOPHENOTYPING; INHIBITOR OF APOPTOSIS PROTEINS; LEUKEMIA, MYELOID, ACUTE; MALE; MICROTUBULE-ASSOCIATED PROTEINS; MIDDLE AGED; P-GLYCOPROTEIN; P-GLYCOPROTEINS; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 77953574612     PISSN: 10245332     EISSN: 16078454     Source Type: Journal    
DOI: 10.1179/102453309X12583347113690     Document Type: Article

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