Parsing the early cytoskeletal and nuclear organizational cues that demarcate stem cell lineages

Cell Cycle

Volumn 9, Issue 11, 2010, Pages 2108-2117

  Liu, Er ^a   Gordonov, Simon ^a   Treiser, Matthew D ^a,c   Moghe, Prabhas V ^a,b  

^a RUTGERS UNIVERSITY   (United States)

^b The State University of New Jersey   (United States)

^c RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

Actin; Cytoskeleton; Gene expression profiling; High content imaging; Nuclear proteins; NuMA; Stem cell differentiation

Indexed keywords

ACTIN BINDING PROTEIN;

CELL CYCLE REGULATION; CELL FUNCTION; CELL LINEAGE; CELL SUBPOPULATION; CONTROLLED STUDY; CYTOSKELETON; GENE CONTROL; GENE EXPRESSION; GENE FUNCTION; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; REVIEW; UPREGULATION;

EID: 77953573816     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.9.11.11864     Document Type: Review

References (45)

1. Treiser MD, Yang EH, Gordonov S, Cohen DM, Androulakis IP, Kohn J, et al. Cytoskeleton-based forecasting of stem cell lineage fates. Proc Natl Acad Sci USA 107:2-5.
2. Caplan AI. Adult mesenchymal stem cells for tissue engineering versus regenerative medicine. J Cell Physiol 2007; 213:341-7.
3. Delorme B, Charbord P. Culture and characterization of human bone marrow mesenchymal stem cells. Methods Mol Med 2007; 140:67-81.
4. Jiang Y, Jahagirdar BN, Reinhardt RL, Schwartz RE, Keene CD, Ortiz-Gonzalez XR, et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002; 418:41-9. (Pubitemid 34742565)
5. Snykers S, Vanhaecke T, Papeleu P, Henkens T, Vinken M, Elaut G, et al. In vitro multipotency of human bone marrow (mesenchymal) stem cells. ALTEX 2006; 23:400-5.
6. Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999; 284:143-7.
7. Curran JM, Chen R, Hunt JA. The guidance of human mesenchymal stem cell differentiation in vitro by controlled modifications to the cell substrate. Biomaterials 2006; 27:4783-93.
8. Reilly GC, Engler AJ. Intrinsic extracellular matrix properties regulate stem cell differentiation. J Biomech 43:55-62.
9. McBeath R, Pirone DM, Nelson CM, Bhadriraju K, Chen CS. Cell shape, cytoskeletal tension and RhoA regulate stem cell lineage commitment. Dev Cell 2004; 6:483-95. (Pubitemid 38456178)
10. Gieni RS, Hendzel MJ. Mechanotransduction from the ECM to the genome: are the pieces now in place? J Cell Biochem 2008; 104:1964-87.
11. Gama-Carvalho M, Carmo-Fonseca M. The rules and roles of nucleocytoplasmic shuttling proteins. FEBS Lett 2001; 498:157-63.
12. Arnaout MA, Goodman SL, Xiong JP. Structure and mechanics of integrin-based cell adhesion. Curr Opin Cell Biol 2007; 19:495-507.
13. El-Bahrawy M, Talbot I, Poulsom R, Alison M. Variable nuclear localization of alpha-catenin in colorectal carcinoma. Lab Invest 2002; 82:1167-74. (Pubitemid 35014850)
14. Ingber D. How cells (might) sense microgravity. FASEB J 1999; 13:3-15. (Pubitemid 129710474)
15. Ingber DE, Prusty D, Sun Z, Betensky H, Wang N. Cell shape, cytoskeletal mechanics and cell cycle control in angiogenesis. J Biomech 1995; 28:1471-84.
16. Abad PC, Lewis J, Mian IS, Knowles DW, Sturgis J, Badve S, et al. NuMA influences higher order chromatin organization in human mammary epithelium. Mol Biol Cell 2007; 18:348-61.
17. Chandramouly G, Abad PC, Knowles DW, Lelievre SA. The control of tissue architecture over nuclear organization is crucial for epithelial cell fate. J Cell Sci 2007; 120:1596-606.
18. Nobes CD, Hall A. Rho, rac and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia and filopodia. Cell 1995; 81:53-62.
19. Maekawa M, Ishizaki T, Boku S, Watanabe N, Fujita A, Iwamatsu A, et al. Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase. Science 1999; 285:895-8.
20. Ohashi K, Nagata K, Maekawa M, Ishizaki T, Narumiya S, Mizuno K. Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop. J Biol Chem 2000; 275:3577-82.
21. Rodriguez JP, Gonzalez M, Rios S, Cambiazo V. Cytoskeletal organization of human mesenchymal stem cells (MSC) changes during their osteogenic differentiation. J Cell Biochem 2004; 93:721-31.
22. Mackay DJ, Esch F, Furthmayr H, Hall A. Rho- and rac-dependent assembly of focal adhesion complexes and actin filaments in permeabilized fibroblasts: an essential role for ezrin/radixin/moesin proteins. J Cell Biol 1997; 138:927-38.
23. Matsui T, Maeda M, Doi Y, Yonemura S, Amano M, Kaibuchi K, Tsukita S. Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association. J Cell Biol 1998; 140:647-57.
24. Crowley JL, Smith TC, Fang Z, Takizawa N, Luna EJ. Supervillin reorganizes the actin cytoskeleton and increases invadopodial efficiency. Mol Biol Cell 2009; 20:948-62.
25. Yu FX, Sun HQ, Janmey PA, Yin HL. Identification of a polyphosphoinositide-binding sequence in an actin monomer-binding domain of gelsolin. J Biol Chem 1992; 267:14616-21.
26. Maatta A, Hutchison CJ, Watson MD. Spectraplakins and nesprins, giant spectrin repeat proteins participating in the organization of the cytoskeleton and the nuclear envelope. Symp Soc Exp Biol 2004:265-77.
27. Sung KL, Yang L, Whittemore DE, Shi Y, Jin G, Hsieh AH, et al. The differential adhesion forces of anterior cruciate and medial collateral ligament fibroblasts: effects of tropomodulin, talin, vinculin and alpha-actinin. Proc Natl Acad Sci USA 1996; 93:9182-7.
28. Ben-Yosef T, Francomano CA. Characterization of the human talin (TLN) gene: genomic structure, chromosomal localization and expression pattern. Genomics 1999; 62:316-9.
29. Humphries JD, Wang P, Streuli C, Geiger B, Humphries MJ, Ballestrem C. Vinculin controls focal adhesion formation by direct interactions with talin and actin. J Cell Biol 2007; 179:1043-57.
30. D'Angelo MA, Hetzer MW. Structure, dynamics and function of nuclear pore complexes. Trends Cell Biol 2008; 18:456-66.
31. Yasuhara N, Oka M, Yoneda Y. The role of the nuclear transport system in cell differentiation. Semin Cell Dev Biol 2009; 20:590-9.
32. Vasu SK, Forbes DJ. Nuclear pores and nuclear assembly. Curr Opin Cell Biol 2001; 13:363-75.
33. Azuma Y, Dasso M. The role of Ran in nuclear function. Curr Opin Cell Biol 2000; 12:302-7.
34. Lelievre SA. Contributions of extracellular matrix signaling and tissue architecture to nuclear mechanisms and spatial organization of gene expression control. Biochim Biophys Acta 2009; 1790:925-35.
35. Dechat T, Pfleghaar K, Sengupta K, Shimi T, Shumaker DK, Solimando L, Goldman RD. Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin. Genes Dev 2008; 22:832-53.
36. Libotte T, Zaim H, Abraham S, Padmakumar VC, Schneider M, Lu W, et al. Lamin A/C-dependent localization of Nesprin-2, a giant scaffolder at the nuclear envelope. Mol Biol Cell 2005; 16:3411-24.
37. Mislow JM, Holaska JM, Kim MS, Lee KK, Segura-Totten M, Wilson KL, McNally EM. Nesprin-1alpha self-associates and binds directly to emerin and lamin A in vitro. FEBS Lett 2002; 525:135-40.
38. Krauss SW, Lo AJ, Short SA, Koury MJ, Mohandas N, Chasis JA. Nuclear substructure reorganization during late-stage erythropoiesis is selective and does not involve caspase cleavage of major nuclear substructural proteins. Blood 2005; 106:2200-5.
39. Nielsen JA, Hudson LD, Armstrong RC. Nuclear organization in differentiating oligodendrocytes. J Cell Sci 2002; 115:4071-9.
40. Spencer VA, Xu R, Bissell MJ. Extracellular matrix, nuclear and chromatin structure and gene expression in normal tissues and malignant tumors: a work in progress. Adv Cancer Res 2007; 97:275-94.
41. Feister HA, Onyia JE, Miles RR, Yang X, Galvin R, Hock JM, Bidwell JP. The expression of the nuclear matrix proteins NuMA, topoisomerase II-alpha, and -beta in bone and osseous cell culture: regulation by parathyroid hormone. Bone 2000; 26:227-34.
42. Taimen P, Viljamaa M, Kallajoki M. Preferential expression of NuMA in the nuclei of proliferating cells. Exp Cell Res 2000; 256:140-9.
43. Liu E, Treiser MD, Patel H, Sung HJ, Roskov KE, Kohn J, et al. High-content profiling of cell responsiveness to graded substrates based on combinyatorially variant polymers. Comb Chem High Throughput Screen 2009; 12:646-55.
44. Treiser MD, Liu E, Dubin RA, Sung HJ, Kohn J, Moghe PV. Profiling cell-biomaterial interactions via cell-based fluororeporter imaging. Biotechniques 2007; 43:361-8.
45. Sun QY, Schatten H. Role of NuMA in vertebrate cells: review of an intriguing multifunctional protein. Front Biosci 2006; 11:1137-46. (Pubitemid 43253465)