Ranibizumab monotherapy for sub-foveal haemorrhage secondary to choroidal neovascularisation in age-related macular degeneration

Eye

Volumn 24, Issue 6, 2010, Pages 994-998

  Mckibbin, M ^a   Papastefanou, V ^a   Matthews, B ^a   Cook, H ^b   Downey, L ^b  

^a ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

^b HULL ROYAL INFIRMARY   (United Kingdom)

Author keywords

Age related macular degeneration; Ranibizumab; Sub foveal haemorrhage

Indexed keywords

RANIBIZUMAB;

AGED; ARTICLE; CLINICAL ARTICLE; DISEASE DURATION; DRUG EFFECT; DRUG EFFICACY; EPIRETINAL MEMBRANE; FEMALE; FOLLOW UP; HUMAN; MALE; MEDICAL RECORD REVIEW; MONOTHERAPY; RETINA MACULA AGE RELATED DEGENERATION; RETINA MACULA HEMORRHAGE; RETROSPECTIVE STUDY; SUBRETINAL NEOVASCULARIZATION; VISUAL ACUITY; VITREOUS HEMORRHAGE;

EID: 77953566972     PISSN: 0950222X     EISSN: 14765454     Source Type: Journal    
DOI: 10.1038/eye.2009.271     Document Type: Article

References (15)

1. Avery R, Fekrat S, Hawkins B, Bressler N. Natural history of subretinal subfoveal haemorrhage in age-related macular degeneration. Retina 1996; 16: 183-189. (Pubitemid 26190846)
2. Bressler NM, Bressler SB, Childs AL, Haller JA, Hawkins BS, Lewis H, et al., Submacular Surgery Trials (SST) Research Group. Surgery for hemorrhagic choroidal neovascular lesions of age-related macular degeneration: ophthalmic findings: SST report no. 13. Ophthalmology 2004; 111(11): 1993-2006.
3. Olivier S, Chow DR, Packo KH, MacCumber MW, Awh CC. Subretinal recombinant tissue plasminogen activator injection and pneumatic displacement of thick submacular hemorrhage in age-related macular degeneration. Ophthalmology 2004; 111(6): 1201-1208.
4. Gopalakrishan M, Giridhar A, Bhat S, Saikumar SJ, Elias A, N S. Pneumatic displacement of submacular hemorrhage: safety, efficacy, and patient selection. Retina 2007; 27(3): 329-334.
5. Singh RP, Patel C, Sears JE. Management of subretinal macular haemorrhage by direct administration of tissue plasminogen activator. Br J Ophthalmol 2006; 90(4): 429-431.
6. Sacu S, Stifter E, Vécsei-Marlovits PV, Michels S, Schütze C, Prünte C et al. Management of extensive subfoveal haemorrhage secondary to neovascular age-related macular degeneration. Eye 2009; 23(6): 1404-1410.
7. Stifter E, Michels S, Prager F, Georgopoulos M, Polak K, Hirn C et al. Intravitreal bevacizumab therapy for neovascular age-related macular degeneration with large submacular hemorrhage. Am J Ophthalmol 2007; 144(6): 886-892.
8. Meyer CH, Scholl HP, Eter N, Helb HM, Holz FG. Combined treatment of acute subretinal haemorrhages with intravitreal recombined tissue plasminogen activator, expansile gas and bevacizumab: a retrospective pilot study. Acta Ophthalmol 2008; 86(5): 490-494.
9. Rosenfeld PJ, Brown DM, Heier JS, Boyer DS, Kaiser PK, Chung CY, et al., MARINA Study Group. Ranibizumab for neovascular age-related macular degeneration. N Engl J Med 2006; 355(14): 1419-1431.
10. Fung AE, Lalwani GA, Rosenfeld PJ, Dubovy SR, Michels S, Feuer WJ et al. An optical coherence tomography-guided, variable dosing regimen with intravitreal ranibizumab (Lucentis) for neovascular age-related macular degeneration. Am J Ophthalmol 2007; 143(4): 566-583.
11. Hattenbach LO, Klais C, Koch FH, Gümbel HO. Intravitreous injection of tissue plasminogen activator and gas in the treatment of submacular hemorrhage under various conditions. Ophthalmology 2001; 108(8): 1485-1492.
12. Schulze SD, Hesse L. Tissue plasminogen activator plus gas injection in patients with subretinal hemorrhage caused by age-related macular degeneration: predictive variables for visual outcome. Graefes Arch Clin Exp Ophthalmol 2002; 240(9): 717-720.
13. Holz FG, Meyer C, Eter N. Safety and efficacy of ranibizumab treatment in patients with neovascular age-related macular degeneration: 12-month results of the SUSTAIN study. Invest Ophthalmol Vis Sci 2009; 50; E-Abstract 3095.
14. Chan CK, Meyer CH, Gross JG, Abraham P, Nuthi AS, Kokame GT et al. Retinal pigment epithelial tears after intravitreal bevacizumab injection for neovascular age-related macular degeneration. Retina 2007; 27(5): 541-551.
15. Goverdhan SV, Lochhead J. Submacular haemorrhages after intravitreal bevacizumab for large occult choroidal neovascularisation in age-related macular degeneration. Br J Ophthalmol 2008; 92(2): 210-212.