Long-term evaluation of chromosomal breakages after radioisotope synovectomy for treatment of target joints in patients with haemophilia

Haemophilia

Volumn 16, Issue 3, 2010, Pages 474-478

  Kavakli, K ^a   Cogulu, O ^a   Aydogdu, S ^a   Ozkilic H ^b   Durmaz, B ^a   Kirbiyik, O ^a   Ozkinay, F ^a   Balkan, C ^a   Karapinar, D ^a   Ay, Y ^a  

^a Department of Pediatric Hematology ^*  (Turkey)

^b EGE UNIVERSITY   (Turkey)

Author keywords

Chromosomal breakages; DEB test; Haemophilia; Radioisotope synovectomy; Rhenium 186; Yttrium 90

Indexed keywords

BUTADIENE DIEPOXIDE; RHENIUM 186; YTTRIUM 90;

ADOLESCENT; ADULT; ARTICLE; CHILD; CHROMOSOME BREAKAGE; CLINICAL ARTICLE; CLINICAL EVALUATION; CYTOGENETICS; FEMALE; GENOTOXICITY; HEMOPHILIA; HUMAN; JOINT; KNEE; MALE; MALIGNANT TRANSFORMATION; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; RADIATION EXPOSURE; RADIOISOTOPE SYNOVECTOMY; SAFETY; SCHOOL CHILD; SYNOVECTOMY;

ADOLESCENT; ADULT; CHILD; CHROMOSOME BREAKAGE; FEMALE; HEMARTHROSIS; HEMOPHILIA A; HEMOPHILIA B; HUMANS; INJECTIONS, INTRA-ARTICULAR; LYMPHOCYTES; MALE; PROSPECTIVE STUDIES; RADIOISOTOPES; RADIOPHARMACEUTICALS; RHENIUM; TRANSFORMATION, GENETIC; YOUNG ADULT; YTTRIUM RADIOISOTOPES;

EID: 77953559395     PISSN: 13518216     EISSN: 13652516     Source Type: Journal    
DOI: 10.1111/j.1365-2516.2009.02167.x     Document Type: Article

References (13)

1. Rodriguez-Merchan EC, Wiedel JD. General principles and indications of synoviorthesis (medical synovectomy) in hemophilia. Haemophilia 2001, 7(Suppl. 2):6-10.
2. Manco-Johnson MJ, Nuss R, Lear J. P 32 radiosynoviothesis in children with hemophilia. J Pediatr Hematol Oncol 2002, 24:534-39.
3. Dunn AL, Busch MT, Bradley JB, Abshire TC. Radioactive synovectomy for hemophilic arthropathy; a comprehensive review of safety and efficacy and recommendations for standardized treatment period. Thromb Haemost 2002, 87:383-93.
4. Kavakli K, Aydogdu S, Omay SB. Long-term evaluation of radioisotope synovectomy with Yttrium 90 for the chronic synovitis in Turkish haemophiliacs: Izmir experience. Haemophilia 2006, 12:28-35.
5. Rodriguez-Merchan EC. Synoviorthesis in hemophilic synovitis: which is the best radioactive material to use? Haemophilia 2004, 10:422-27.
6. Kavakli K, Aydogdu S, Taner M. Radioisotope synovectomy with rhenium 186 in hemophilic synovitis for elbows, ankles and shoulders. Haemophilia 2008, 14:518-23.
7. Dunn A, Manco-Johnson MJ, Busch MT, Abshire T. Leukemia and P32 radionuclid synovectomy for hemophilic arthropathy. J Thromb Haemost 2005, 3:1541-42.
8. Rooney DE. Human Cytogenetics: Constitutional analysis 2001, 3rd edn, Oxford, Oxford University Press
9. Falcon de Vargas A, Fernandez-Palazzi F. Cytogenetic studies in patients in patients with hemophilic hemarthrosis treated by 198Au, 186Rh and 90Y radioactive synoviorthesis. J Pediatr Orthop 2000, 9:52-4.
10. Fernandez-Palazzi F, Caviglia H. On the safety of synoviorthesis in hemophilia. Haemophilia 2001, 7(Suppl. 2):50-3.
11. Gedik GK, Ugur O, Atilla B. Comparison of extraarticular leakage values of radiopharmaceuticals used for radionuclide synovectomy. Ann Nucl Med 2006, 20:183-8.
12. Esmer C, Sánchez S, Ramos S, Molina B, Frias S, Carnevale A. DEB test for Fanconi anemia detection in patients with atypical phenotypes. Am J Med Genet A 2004, 124A:35-9.
13. Turkmen C, Ozturk S, Unal SN. Monitoring the genotoxic effects of radiosynovectomy with Re 186 in pediatric age group undergoing therapy for hemophilic synovitis. Haemophilia 2007, 13:57-64.