Unfavourable clinicopathologic features and low response rate to systemic adjuvant therapy: Results with regard to poor survival in young Chinese breast cancer patients

Breast Cancer Research and Treatment

Volumn 122, Issue 1, 2010, Pages 95-104

  Tang, Li Chen ^a   Yin, Wen Jin ^a   Di, Gen Hong ^a   Shen, Zhen Zhou ^a   Shao, Zhi Ming ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Breast cancer; Characteristics; Survival; Therapy; Young women

Indexed keywords

ANTHRACYCLINE ANTIBIOTIC AGENT; ANTINEOPLASTIC AGENT; AROMATASE INHIBITOR; CATHEPSIN D; CYCLINE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; METHOTREXATE; PROGESTERONE RECEPTOR; PROTEIN P53; TAXANE DERIVATIVE;

ADJUVANT THERAPY; ADULT; AGE; ARTICLE; BREAST CANCER; CANCER CENTER; CANCER GRADING; CANCER MORTALITY; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER STAGING; CANCER SURVIVAL; CHINA; CHINESE; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE FREE SURVIVAL; FEMALE; GENE OVEREXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MASTECTOMY; METASTASIS POTENTIAL; MULTIPLE CYCLE TREATMENT; OVERALL SURVIVAL; PARTIAL MASTECTOMY; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; TREATMENT OUTCOME; TUMOR VOLUME; UNIVERSITY HOSPITAL; ADJUVANT CHEMOTHERAPY; BREAST NEOPLASMS; CARCINOMA; EPIDEMIOLOGY; FOLLOW UP; KAPLAN MEIER METHOD; MIDDLE AGED; MORTALITY; MULTIMODALITY CANCER THERAPY; OVARIECTOMY; PATHOLOGY; PATIENT SELECTION; PROPORTIONAL HAZARDS MODEL;

ADULT; AGE FACTORS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BREAST NEOPLASMS; CARCINOMA; CHEMOTHERAPY, ADJUVANT; CHINA; COMBINED MODALITY THERAPY; DISEASE-FREE SURVIVAL; FEMALE; FOLLOW-UP STUDIES; HUMANS; KAPLAN-MEIERS ESTIMATE; MASTECTOMY; MIDDLE AGED; OVARIECTOMY; PATIENT SELECTION; PROPORTIONAL HAZARDS MODELS; RADIOTHERAPY, ADJUVANT; KAPLAN-MEIER ESTIMATE;

EID: 77953542834     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-009-0537-4     Document Type: Article

References (29)

1. A Jemal R Siegel E Ward Y Hao J Xu T Murray MJ Thun 2008 Cancer statistics, 2008 CA Cancer J Clin 58 71 96 10.3322/CA.2007.0010 18287387 (Pubitemid 351521864)
2. Fan L, Zheng Y, Yu KD, Liu GY, Wu J, Lu JS, Shen KW, Shen ZZ, Shao ZM (2009) Breast cancer in a transitional society over 18 years: trends and present status in Shanghai, China. Breast Cancer Res Treat 117:409-416
3. LA Brinton ME Sherman JD Carreon WF Anderson 2008 Recent trends in breast cancer among younger women in the United States J Natl Cancer Inst 100 1643 1648 10.1093/jnci/djn344 19001605
4. M Colonna P Delafosse Z Uhry F Poncet P Arveux F Molinie L Cherie-Challine P Grosclaude 2008 Is breast cancer incidence increasing among young women? An analysis of the trend in France for the period 1983-2002 Breast 17 289 292 10.1016/j.breast.2007.10.017 18053721
5. BC Yankaskas 2005 Epidemiology of breast cancer in young women Breast Dis 23 3 8 16823161
6. SH Ahn BH Son SW Kim SI Kim J Jeong SS Ko W Han 2007 Poor outcome of hormone receptor-positive breast cancer at very young age is due to tamoxifen resistance: nationwide survival data in Korea-a report from the Korean Breast Cancer Society J Clin Oncol 25 2360 2368 10.1200/JCO.2006.10.3754 17515570 (Pubitemid 47007614)
7. D Axelrod J Smith D Kornreich E Grinstead B Singh J Cangiarella AA Guth 2008 Breast cancer in young women J Am Coll Surg 206 1193 1203 10.1016/j.jamcollsurg.2007.12.026 18501818
8. AJ Nixon D Neuberg DF Hayes R Gelman JL Connolly S Schnitt A Abner A Recht F Vicini JR Harris 1994 Relationship of patient age to pathologic features of the tumor and prognosis for patients with stage I or II breast cancer J Clin Oncol 12 888 894 1:STN:280:DyaK2c3hs12gtA%3D%3D 8164038 (Pubitemid 24145313)
9. E Rapiti G Fioretta HM Verkooijen G Vlastos P Schafer AP Sappino J Kurtz I Neyroud-Caspar C Bouchardy 2005 Survival of young and older breast cancer patients in Geneva from 1990 to 2001 Eur J Cancer 41 1446 1452 10.1016/j.ejca.2005.02.029 15919199 (Pubitemid 40826469)
10. LM McShane DG Altman W Sauerbrei SE Taube M Gion GM Clark 2005 Reporting recommendations for tumor marker prognostic studies (REMARK) J Natl Cancer Inst 97 1180 1184 1:CAS:528:DC%2BD2MXpsVaks7s%3D 16106022 (Pubitemid 41258223)
11. PC Dubsky MF Gnant S Taucher S Roka D Kandioler B Pichler-Gebhard I Agstner M Seifert P Sevelda R Jakesz 2002 Young age as an independent adverse prognostic factor in premenopausal patients with breast cancer Clin Breast Cancer 3 65 72 10.3816/CBC.2002.n.013 12020397
12. A Sidoni A Cavaliere G Bellezza M Scheibel E Bucciarelli 2003 Breast cancer in young women: clinicopathological features and biological specificity Breast 12 247 250 10.1016/S0960-9776(03)00095-X 1:STN:280:DC%2BD3srnvV2jsw%3D%3D 14659308 (Pubitemid 36944150)
13. MA Maggard JB O'Connell KE Lane JH Liu DA Etzioni CY Ko 2003 Do young breast cancer patients have worse outcomes? J Surg Res 113 109 113 10.1016/S0022-4804(03)00179-3 12943818 (Pubitemid 36999799)
14. L Vanlemmens M Hebbar JP Peyrat J Bonneterre 1998 Age as a prognostic factor in breast cancer Anticancer Res 18 1891 1896 1:STN:280: DyaK1czkt1Cjtg%3D%3D 9677440
15. A Goldhirsch RD Gelber G Yothers RJ Gray S Green J Bryant S Gelber M Castiglione-Gertsch AS Coates 2001 Adjuvant therapy for very young women with breast cancer: need for tailored treatments J Natl Cancer Inst Monogr 4 4 51
16. M Colleoni N Rotmensz G Peruzzotti P Maisonneuve L Orlando R Ghisini G Viale G Pruneri P Veronesi A Luini M Intra A Cardillo R Torrisi A Rocca A Goldhirsch 2006 Role of endocrine responsiveness and adjuvant therapy in very young women (below 35 years) with operable breast cancer and node negative disease Ann Oncol 17 1497 1503 10.1093/annonc/mdl145 1:STN:280: DC%2BD28rnsFyltQ%3D%3D 16798834 (Pubitemid 44542034)
17. RA Walker E Lees MB Webb SJ Dearing 1996 Breast carcinomas occurring in young women (<35 years) are different Br J Cancer 74 1796 1800 1:STN:280:DyaK2s7hsFeqtg%3D%3D 8956795
18. KS Albain DC Allred GM Clark 1994 Breast cancer outcome and predictors of outcome: are there age differentials? J Natl Cancer Inst Monogr 3 5 42
19. KD Yu GH Di J Wu JS Lu KW Shen ZZ Shen ZM Shao 2007 Development and trends of surgical modalities for breast cancer in China: a review of 16-year data Ann Surg Oncol 14 2502 2509 10.1245/s10434-007-9436-2 17564750 (Pubitemid 47389574)
20. S Aebi S Gelber M Castiglione-Gertsch RD Gelber J Collins B Thurlimann CM Rudenstam J Lindtner D Crivellari H Cortes-Funes E Simoncini ID Werner AS Coates A Goldhirsch 2000 Is chemotherapy alone adequate for young women with oestrogen-receptor-positive breast cancer? Lancet 355 1869 1874 10.1016/S0140-6736(00)02292-3 1:CAS:528:DC%2BD3cXkt1Crsbs%3D 10866443
21. M Colleoni N Rotmensz C Robertson L Orlando G Viale G Renne A Luini P Veronesi M Intra R Orecchia G Catalano V Galimberti F Nole G Martinelli A Goldhirsch 2002 Very young women (<35 years) with operable breast cancer: features of disease at presentation Ann Oncol 13 273 279 10.1093/annonc/mdf039 1:STN:280:DC%2BD387ltl2gtw%3D%3D 11886005
22. W Han SW Kim IA Park D Kang YK Youn SK Oh KJ Choe DY Noh 2004 Young age: an independent risk factor for disease-free survival in women with operable breast cancer BMC Cancer 4 82 10.1186/1471-2407-4-82 15546499 (Pubitemid 40180272)
23. A Goldhirsch WC Wood RD Gelber AS Coates B Thurlimann HJ Senn 2007 Progress and promise: highlights of the international expert consensus on the primary therapy of early breast cancer 2007 Ann Oncol 18 1133 1144 10.1093/annonc/mdm271 1:STN:280:DC%2BD2svlvVSkuw%3D%3D 17675394 (Pubitemid 47244357)
24. A de la Rochefordiere B Asselain F Campana SM Scholl J Fenton JR Vilcoq JC Durand P Pouillart H Magdelenat A Fourquet 1993 Age as prognostic factor in premenopausal breast carcinoma Lancet 341 1039 1043 10.1016/0140-6736(93)92407-K (Pubitemid 23114394)
25. P Bonnier S Romain C Charpin C Lejeune N Tubiana PM Martin L Piana 1995 Age as a prognostic factor in breast cancer: relationship to pathologic and biologic features Int J Cancer 62 138 144 10.1002/ijc.2910620205 1:STN:280:DyaK2Mzkslyrsw%3D%3D 7622286
26. RR Love NB Duc NV Dinh TT Quy Y Xin TC Havighurst 2002 Young age as an adverse prognostic factor in premenopausal women with operable breast cancer Clin Breast Cancer 2 294 298 10.3816/CBC.2002.n.005 11899361
27. N Kroman MB Jensen J Wohlfahrt HT Mouridsen PK Andersen M Melbye 2000 Factors influencing the effect of age on prognosis in breast cancer: population based study BMJ 320 474 478 10.1136/bmj.320.7233.474 1:STN:280: DC%2BD3c7ktlKitw%3D%3D 10678859
28. LI van't Veer H Dai MJ van de Vijver YD He AA Hart M Mao HL Peterse K van der Kooy MJ Marton AT Witteveen GJ Schreiber RM Kerkhoven C Roberts PS Linsley R Bernards SH Friend 2002 Gene expression profiling predicts clinical outcome of breast cancer Nature 415 530 536 10.1038/415530a (Pubitemid 34130608)
29. N Klauber-DeMore 2005 Tumor biology of breast cancer in young women Breast Dis 23 9 15 16823162