Improving the therapeutic ratio in head and neck cancer

The Lancet Oncology

Volumn 11, Issue 6, 2010, Pages 512-513

  Prestwich, Robin ^a   Dyker, Karen ^a   Sen, Mehmet ^a  

^a ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BETA TUBULIN; BIOLOGICAL MARKER; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; HYPOXIA INDUCIBLE FACTOR 1; OXYGEN; PLATINUM COMPLEX; RIBONUCLEOTIDE REDUCTASE; TAXANE DERIVATIVE;

CANCER RADIOTHERAPY; CONTRAST ENHANCEMENT; DRUG RESEARCH; HEAD AND NECK CANCER; HEAD AND NECK SURGERY; HUMAN; HYPOXIA; INDIVIDUALIZATION; LETTER; MEDICAL DECISION MAKING; NUCLEAR MAGNETIC RESONANCE IMAGING; PATIENT CARE; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; TREATMENT OUTCOME;

CARCINOMA, SQUAMOUS CELL; HEAD AND NECK NEOPLASMS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INDIVIDUALIZED MEDICINE; PROGNOSIS;

EID: 77953532463     PISSN: 14702045     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1470-2045(10)70060-7     Document Type: Letter

References (5)

1. Corry J, Peters LJ, Rischin D Optimising the therapeutic ratio in head and neck cancer. Lancet Oncol 2010, 11:287-291.
2. Silva P, Slevin NJ, Sloan P, et al. Prognostic significance of tumor hypoxia inducible factor-1α expression for outcome after radiotherapy in oropharyngeal cancer. Int J Radiation Biol Phys 2008, 72:1551-1559.
3. Beasley NK, Leek R, Alam M, et al. Hypoxia-inducible factors HIF-1alpha and HIF-2alpha in head and neck cancer: relationship to tumour biology and treatment outcome in surgically resected patients. Cancer Res 2002, 62:2493-2497.
4. Newbold K, Castellano I, Charles-Edwards E, et al. An exploratory study into the role of dynamic contrast-enhanced magnetic resonance imaging or perfusion computed tomography for detection of intratumoral hypoxia in head-and-neck cancer. Int J Radiation Biol Phys 2009, 74:29-37.
5. Jun HJ, Ahn MJ, Kim HS, et al. ERCC1 expression as a predictive marker of squamous cell carcinoma of the head and neck treated with cisplatin-based concurrent chemoradiation. Br J Cancer 2008, 99:167-172.