Glucocerebrosidase deficiency dramatically impairs human bone marrow haematopoiesis in an in vitro model of Gaucher disease: Research paper

British Journal of Haematology

Volumn 150, Issue 1, 2010, Pages 93-101

  Berger, Juliette ^a,b   Lecourt, Séverine ^c,d   Vanneaux, Valérie ^c   Rapatel, Chantal ^a   Boisgard, Stéphane ^e   Caillaud, Catherine ^f   Boiret Dupré, Nathalie ^a,b   Chomienne, Christine ^d   Marolleau, Jean Pierre ^g   Larghero, Jérôme ^c,d   Berger, Marc G ^a,b  

^a UNIVERSITY HOSPITAL OF CLERMONT FERRAND   (France)

^b UNIVERSITÉ CLERMONT AUVERGNE   (France)

^c SAINT LOUIS HOSPITAL   (France)

^d INSERM   (France)

^e SERVICE DE RHUMATOLOGIE   (France)

^f Institut Cochin   (France)

^g AMIENS UNIVERSITY HOSPITAL   (France)

Author keywords

Cytopenia; Gaucher disease; Glucocerebrosidase activity; Haematopoiesis; Long term culture initiating cells (LTC IC)

Indexed keywords

GLUCOSYLCERAMIDASE;

ARTICLE; BLOOD CELL; BONE MARROW CELL; CD34 SELECTION; CELL CULTURE; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; COLONY FORMING UNIT; COLONY FORMING UNIT GM; CONTROLLED STUDY; CYTOPENIA; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME INHIBITION; FLOW CYTOMETRY; GAUCHER DISEASE; GLUCOSYLCERAMIDASE DEFICIENCY; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MEGAKARYOCYTE ERYTHROID PROGENITOR; NORMAL HUMAN; PRIORITY JOURNAL;

BONE MARROW CELLS; CELL PROLIFERATION; CELLS, CULTURED; COLONY-FORMING UNITS ASSAY; ENZYME INHIBITORS; FLOW CYTOMETRY; GAUCHER DISEASE; GLUCOSYLCERAMIDASE; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HUMANS; INOSITOL; MODELS, BIOLOGICAL; TISSUE CULTURE TECHNIQUES;

EID: 77953530686     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2010.08214.x     Document Type: Article

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