Development of quantitative-fluorescence polymerase chain reaction for the rapid prenatal diagnosis of common chromosomal aneuploidies in 1,000 samples in Singapore

Singapore Medical Journal

Volumn 51, Issue 4, 2010, Pages 343-348

  Baig, S ^a   Ho, S S Y ^a   Ng, B L ^a   Chiu, L ^c   Koay, E S C ^c   Leow, G H ^c   Gole, L ^a   Kothandaraman, N ^a   Chan, J ^d   Sun, X ^d   Chan, Y H ^b   Rauff, M ^a   Su, L L ^a   Biswas, A ^a   Choolani, M ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b Biostatistics Unit

^c NATIONAL UNIVERSITY HOSPITAL   (Singapore)

^d Department of Laboratory Medicine ^*

Author keywords

Amniocentesis; Down syndrome; FISH; Karyotype; Short tandem repeat

Indexed keywords

GENOMIC DNA; MICROSATELLITE DNA;

AMNION FLUID; ANEUPLOIDY; ANXIETY; ARTICLE; BLOOD SAMPLING; CHORION VILLUS; CHROMOSOME 13; CHROMOSOME 18; CHROMOSOME 21; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DNA DETERMINATION; DOWN SYNDROME; EDWARDS SYNDROME; FETUS; HETEROZYGOSITY; HUMAN; KARYOTYPE; MICROSATELLITE MARKER; PARENTAL BEHAVIOR; PATAU SYNDROME; POLYMERASE CHAIN REACTION; PRENATAL DIAGNOSIS; QUANTITATIVE FLUORESCENCE POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; SHORT TANDEM REPEAT; SINGAPORE; TRISOMY; X CHROMOSOME; Y CHROMOSOME; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENETIC POLYMORPHISM; HETEROZYGOTE; KARYOTYPING; MALE; PREGNANCY; PROCEDURES;

FEMALE; HETEROZYGOTE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; KARYOTYPING; MALE; MICROSATELLITE REPEATS; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; PREGNANCY; PRENATAL DIAGNOSIS; SENSITIVITY AND SPECIFICITY; SINGAPORE;

EID: 77953520232     PISSN: 00375675     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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