Simultaneous RP-HPLC-DAD quantification of bromocriptine, haloperidol and its diazepane structural analog in rat plasma with droperidol as internal standard for application to drug-interaction pharmacokinetics

Biomedical Chromatography

Volumn 24, Issue 7, 2010, Pages 699-705

  Billups, Johnique ^a   Jones, Cynthia ^a   Jackson, Tanise L ^a   Ablordeppey, Seth Y ^a   Spencer, Shawn D ^a  

^a FLORIDA A AND M UNIVERSITY   (United States)

Author keywords

Bromocriptine; Diazepane analog; Droperidol; Haloperidol; HPLC DAD

Indexed keywords

ACETONITRILE; AMINES; BODY FLUIDS; CHLORINE COMPOUNDS; DEIONIZED WATER; DRUG INTERACTIONS; NEUROPHYSIOLOGY; RATS;

BROMOCRIPTINE; DIAZEPANE ANALOG; DOPAMINE; DROPERIDOL; HALOPERIDOL; HPLC/DAD; INTERNAL STANDARDS; RAT PLASMA; RP-HPLC; STRUCTURAL ANALOGUE;

PHARMACOKINETICS;

ACETONITRILE; BROMOCRIPTINE; CHLOROFORM; DIAZEPANE; DROPERIDOL; HALOPERIDOL; HEXANE; NEUROLEPTIC AGENT; TRIFLUOROACETIC ACID; UNCLASSIFIED DRUG; WATER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DIODE; DRUG ACTIVITY; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG STRUCTURE; LIQUID LIQUID EXTRACTION; MALE; NONHUMAN; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SINGLE DRUG DOSE;

RATTUS;

EID: 77953513703     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1349     Document Type: Article

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