-
1
-
-
0037096906
-
The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the beta-catenin signaling cascade
-
Albuquerque C, Breukel C, van der Luijt R, Fidalgo P, Lage P, Slors FJ, Leitão CN, Fodde R, Smits R. 2002a. The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the beta-catenin signaling cascade. Hum Mol Genet 11:1549-1560.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 1549-1560
-
-
Albuquerque, C.1
Breukel, C.2
Van Der Luijt, R.3
Fidalgo, P.4
Lage, P.5
Slors, F.J.6
Leitão, C.N.7
Fodde, R.8
Smits, R.9
-
2
-
-
0036257335
-
Genetic characterisation of patients with multiple colonic polyps [6]
-
Albuquerque C, Cravo M, Cruz C, Lage P, Chaves P, Fidalgo P, Suspiro A, Nobre Leitão C. 2002b. Genetic characterization of patients with multiple colonic polyps. J Med Genet 39:297-302. (Pubitemid 34496810)
-
(2002)
Journal of Medical Genetics
, vol.39
, Issue.4
, pp. 297-302
-
-
Albuquerque, C.1
Cravo, M.2
Cruz, C.3
Lage, P.4
Chaves, P.5
Fidalgo, P.6
Suspiro, A.7
Nobre Leitao, C.8
-
3
-
-
0028246570
-
APC and p53 mutations in de novo colorectal adenocarcinomas
-
DOI 10.1002/humu.1380030403
-
Aoki T, Takeda S, Yanagisawa A, Kato Y, Ajioka Y, Watanabe H, Kudo S, Nakamura Y. 1994. APC and p53 mutations in de novo colorectal adenocarcinomas. Hum Mutat 3:342-346. (Pubitemid 24198824)
-
(1994)
Human Mutation
, vol.3
, Issue.4
, pp. 342-346
-
-
Aoki, T.1
Takeda, S.2
Yanagisawa, A.3
Kato, Y.4
Ajioka, Y.5
Watanabe, H.6
Kudo, S.7
Nakamura, Y.8
-
4
-
-
0036500176
-
The APC/beta-catenin pathway in ulcerative colitis-related colorectal carcinomas: A mutational analysis
-
DOI 10.1002/cncr.10334
-
Aust DE, Terdiman JP, Willenbucher RF, Chang CG, Molinaro- Clark A, Baretton GB, Loehrs U, Waldman FM. 2002. The APC/beta-catenin pathway in ulcerative colitis-related colorectal carcinomas: a mutational analysis. Cancer 94:1421-1427. (Pubitemid 34212635)
-
(2002)
Cancer
, vol.94
, Issue.5
, pp. 1421-1427
-
-
Aust, D.E.1
Terdiman, J.P.2
Willenbucher, R.F.3
Chang, C.G.4
Molinaro-Clark, A.5
Baretton, G.B.6
Loehrs, U.7
Waldman, F.M.8
-
5
-
-
43149117058
-
Hyperinduction of Wnt activity: A new paradigm for the treatment of colorectal cancer?
-
Bordonaro M, Lazarova DL, Sartorelli AC. 2008. Hyperinduction of Wnt activity: A new paradigm for the treatment of colorectal cancer? Oncol Res 17:1-9.
-
(2008)
Oncol Res
, vol.17
, pp. 1-9
-
-
Bordonaro, M.1
Lazarova, D.L.2
Sartorelli, A.C.3
-
6
-
-
76749147440
-
Genetic dissection of differential signaling threshold requirements for the Wnt/ beta-catenin pathway in vivo
-
Buchert M, Athineos D, Abud HE, Burke ZD, Faux MC, Samuel MS, Jarnicki AG, Winbanks CE, Newton IP, Meniel VS, Suzuki H, Stacker SA, Näthke IS, Tosh D, Huelsken J, Clarke AR, Heath JK, Sansom OJ, Ernst M. 2010. Genetic dissection of differential signaling threshold requirements for the Wnt/ beta-catenin pathway in vivo. PLoS Genet 6:e1000816.
-
(2010)
PLoS Genet
, vol.6
-
-
Buchert, M.1
Athineos, D.2
Abud, H.E.3
Burke, Z.D.4
Faux, M.C.5
Samuel, M.S.6
Jarnicki, A.G.7
Winbanks, C.E.8
Newton, I.P.9
Meniel, V.S.10
Suzuki, H.11
Stacker, S.A.12
Näthke, I.S.13
Tosh, D.14
Huelsken, J.15
Clarke, A.R.16
Heath, J.K.17
Sansom, O.J.18
Ernst, M.19
-
7
-
-
33746803311
-
Wnt pathway mutations selected by optimal beta-catenin signaling for tumorigenesis
-
DOI 10.1016/j.febslet.2006.05.053, PII S0014579306006661
-
Cho KH, Baek S, Sung MH. 2006. Wnt pathway mutations selected by optimal beta-catenin signaling for tumorigenesis. FEBS Lett 580:3665-3670. (Pubitemid 44183807)
-
(2006)
FEBS Letters
, vol.580
, Issue.15
, pp. 3665-3670
-
-
Cho, K.-H.1
Baek, S.2
Sung, M.-H.3
-
8
-
-
0037699438
-
Refining the relation between 'first hits' and 'second hits' at the APC locus: The 'loose fit' model and evidence for differences in somatic mutation spectra among patients
-
Crabtree M, Sieber OM, Lipton L, Hodgson SV, Lamlum H, Thomas HJ, Neale K, Phillips RK, Heinimann K, Tomlinson IP. 2003. Refining the relation between 'first hits' and 'second hits' at the APC locus: The 'loose fit' model and evidence for differences in somatic mutation spectra among patients. Oncogene 22:4257-4265.
-
(2003)
Oncogene
, vol.22
, pp. 4257-4265
-
-
Crabtree, M.1
Sieber, O.M.2
Lipton, L.3
Hodgson, S.V.4
Lamlum, H.5
Thomas, H.J.6
Neale, K.7
Phillips, R.K.8
Heinimann, K.9
Tomlinson, I.P.10
-
9
-
-
0037340399
-
The multiple functions of tumour suppressors: It's all in APC
-
DOI 10.1038/ncb0303-190
-
Fodde R. 2003. The multiple functions of tumor suppressors: It's all in APC. Nat Cell Bio 5:190-192. (Pubitemid 36322244)
-
(2003)
Nature Cell Biology
, vol.5
, Issue.3
, pp. 190-192
-
-
Fodde, R.1
-
10
-
-
0026674403
-
Eight novel inactivating germ line mutations at the APC gene identified by denaturing gradient gel electrophoresis
-
Fodde R, van der Luijt R, Wijnen J, Tops C, van der Klift H, van Leeuwen-Cornelisse I, Griffioen G, Vasen H, Khan PM. 1992. Eight novel inactivating germ line mutations at the APC gene identified by denaturing gradient gel electrophoresis. Genomics 13:1162-1168.
-
(1992)
Genomics
, vol.13
, pp. 1162-1168
-
-
Fodde, R.1
Van Der Luijt, R.2
Wijnen, J.3
Tops, C.4
Van Der Klift, H.5
Van Leeuwen-Cornelisse, I.6
Griffioen, G.7
Vasen, H.8
Khan, P.M.9
-
11
-
-
0035496104
-
APC, signal transduction and genetic instability in colorectal cancer
-
Fodde R, Smits R, Clevers H. 2001. APC, signal transduction and genetic instability in colorectal cancer. Nat Rev Cancer 1:55-67. (Pubitemid 33741881)
-
(2001)
Nature Reviews Cancer
, vol.1
, Issue.1
, pp. 55-67
-
-
Fodde, R.1
Smits, R.2
Clevers, H.3
-
12
-
-
68249083454
-
A targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumorigenesis
-
Gaspar C, Franken P, Molenaar L, Breukel C, van der Valk M, Smits R, Fodde R. 2009. A targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumorigenesis. PLoS Genet 5:e1000547.
-
(2009)
PLoS Genet
, vol.5
-
-
Gaspar, C.1
Franken, P.2
Molenaar, L.3
Breukel, C.4
Van Der Valk, M.5
Smits, R.6
Fodde, R.7
-
13
-
-
5044220575
-
Chromosomal instability and APC gene mutations in human sporadic colorectal adenomas
-
DOI 10.1002/path.1623
-
Giaretti W, Venesio T, Prevosto C, Lombardo F, Ceccarelli J, Molinu S, Risio M. 2004. Chromosomal instability and APC gene mutations in human sporadic colorectal adenomas. J Pathol 204:193-199. (Pubitemid 39335293)
-
(2004)
Journal of Pathology
, vol.204
, Issue.2
, pp. 193-199
-
-
Giaretti, W.1
Venesio, T.2
Prevosto, C.3
Lombardo, F.4
Ceccarelli, J.5
Molinu, S.6
Risio, M.7
-
14
-
-
0036089371
-
Mutation cluster region, association between germline and somatic mutations and genotype-phenotype correlation in upper gastrointestinal familial adenomatous polyposis
-
Groves C, Lamlum H, Crabtree M, Williamson J, Taylor C, Bass S, Cuthbert-Heavens D, Hodgson S, Phillips R, Tomlinson I. 2002. Mutation cluster region, association between germline and somatic mutations and genotype-phenotype correlation in upper gastrointestinal familial adenomatous polyposis. Am J Pathol 160:2055-2061.
-
(2002)
Am J Pathol
, vol.160
, pp. 2055-2061
-
-
Groves, C.1
Lamlum, H.2
Crabtree, M.3
Williamson, J.4
Taylor, C.5
Bass, S.6
Cuthbert-Heavens, D.7
Hodgson, S.8
Phillips, R.9
Tomlinson, I.10
-
15
-
-
0043028251
-
Distinguishing right from left colon by the pattern of gene expression
-
Glebov OK, Rodriguez LM, Nakahara K, Jenkins J, Cliatt J, Humbyrd CJ, DeNobille J, Soballe P, Simon R, Wright G, Lynch P, Patterson S, Lynch H, Gallinger S, Buchbinder A, Gordon G, Hawk E, Kirsch IR. 2003. Distinguishing right from left colon by the pattern of gene expression. Cancer Epidemiol Biomark Prev 12:755-762.
-
(2003)
Cancer Epidemiol Biomark Prev
, vol.12
, pp. 755-762
-
-
Glebov, O.K.1
Rodriguez, L.M.2
Nakahara, K.3
Jenkins, J.4
Cliatt, J.5
Humbyrd, C.J.6
DeNobille, J.7
Soballe, P.8
Simon, R.9
Wright, G.10
Lynch, P.11
Patterson, S.12
Lynch, H.13
Gallinger, S.14
Buchbinder, A.15
Gordon, G.16
Hawk, E.17
Kirsch, I.R.18
-
16
-
-
3042829472
-
Tumor regionality in the mouse intestine reflects the mechanism of loss of Apc function
-
Haigis KM, Hoff PD, White A, Shoemaker AR, Halberg RB, Dove WF. 2004. Tumor regionality in the mouse intestine reflects the mechanism of loss of Apc function. Proc Natl Acad Sci USA 101:9769-9773.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 9769-9773
-
-
Haigis, K.M.1
Hoff, P.D.2
White, A.3
Shoemaker, A.R.4
Halberg, R.B.5
Dove, W.F.6
-
17
-
-
3142554288
-
My approach to serrated polyps of the colorectum
-
Higuchi T, Jass JR. 2004. My approach to serrated polyps of the colorectum. J Clin Pathol 57:682-686.
-
(2004)
J Clin Pathol
, vol.57
, pp. 682-686
-
-
Higuchi, T.1
Jass, J.R.2
-
18
-
-
0031908348
-
Defects in mismatch repair occur after APC mutations in the pathogenesis of sporadic colorectal tumors
-
Homfray TF, Cottrell SE, Ilyas M, Rowan A, Talbot IC, Bodmer WF, Tomlinson IP. 1998. Defects in mismatch repair occur after APC mutations in the pathogenesis of sporadic colorectal tumors. Hum Mutat 11:114-120.
-
(1998)
Hum Mutat
, vol.11
, pp. 114-120
-
-
Homfray, T.F.1
Cottrell, S.E.2
Ilyas, M.3
Rowan, A.4
Talbot, I.C.5
Bodmer, W.F.6
Tomlinson, I.P.7
-
19
-
-
0010945939
-
APC mutations in colorectal tumors with mismatch repair deficiency
-
Huang J, Papadopoulos N, McKinley AJ, Farrington SM, Curtis LJ, Wyllie AH, Zheng S, Willson JK, Markowitz SD, Morin P, Kinzler KW, Vogelstein B, Dunlop MG. 1996. APC mutations in colorectal tumors with mismatch repair deficiency. Proc Natl Acad Sci USA 93:9049-9054.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 9049-9054
-
-
Huang, J.1
Papadopoulos, N.2
McKinley, A.J.3
Farrington, S.M.4
Curtis, L.J.5
Wyllie, A.H.6
Zheng, S.7
Willson, J.K.8
Markowitz, S.D.9
Morin, P.10
Kinzler, K.W.11
Vogelstein, B.12
Dunlop, M.G.13
-
20
-
-
1842587618
-
Somatic mutations of APC gene in carcinomas from hereditary non-polyposis colorectal cancer patients
-
Huang J, Zheng S, Jin S-H, Zhang S-Z. 2004. Somatic mutations of APC gene in carcinomas from hereditary non-polyposis colorectal cancer patients. World J Gastroenterol 10:834-836.
-
(2004)
World J Gastroenterol
, vol.10
, pp. 834-836
-
-
Huang, J.1
Zheng, S.2
Jin, S.-H.3
Zhang, S.-Z.4
-
21
-
-
19944432960
-
Exon 3 beta-catenin mutations are specifically associated with colorectal carcinomas in hereditary non-polyposis colorectal cancer syndrome
-
Johnson V, Volikos E, Halford SE, Eftekhar Sadat ET, Popat S, Talbot I, Truninger K, Martin J, Jass J, Houlston R, Atkin W, Tomlinson IP, Silver AR. 2005. Exon 3 beta-catenin mutations are specifically associated with colorectal carcinomas in hereditary non-polyposis colorectal cancer syndrome. Gut 54:264-267.
-
(2005)
Gut
, vol.54
, pp. 264-267
-
-
Johnson, V.1
Volikos, E.2
Halford, S.E.3
Eftekhar Sadat, E.T.4
Popat, S.5
Talbot, I.6
Truninger, K.7
Martin, J.8
Jass, J.9
Houlston, R.10
Atkin, W.11
Tomlinson, I.P.12
Silver, A.R.13
-
22
-
-
0033790502
-
Overexpression of beta-catenin induces apoptosis independent of its transactivation function with LEF-1 or the involvement of major G1 cell cycle regulators
-
Kim K, Pang KM, Evans M, Hay ED. 2000. Overexpression of beta-catenin induces apoptosis independent of its transactivation function with LEF-1 or the involvement of major G1 cell cycle regulators. Mol Biol Cell 11:3509-3523.
-
(2000)
Mol Biol Cell
, vol.11
, pp. 3509-3523
-
-
Kim, K.1
Pang, K.M.2
Evans, M.3
Hay, E.D.4
-
23
-
-
0030813048
-
Mutations in beta-catenin are uncommon in colorectal cancer occurring in occasional replication error-positive tumors
-
Kitaeva MN, Grogan L, Williams JP, Dimond E, Nakahara K, Hausner P, DeNobile JW, Soballe PW, Kirsch IR. 1997. Mutations in beta-catenin are uncommon in colorectal cancer occurring in occasional replication error-positive tumors. Cancer Res 57:4478-4481.
-
(1997)
Cancer Res
, vol.57
, pp. 4478-4481
-
-
Kitaeva, M.N.1
Grogan, L.2
Williams, J.P.3
Dimond, E.4
Nakahara, K.5
Hausner, P.6
DeNobile, J.W.7
Soballe, P.W.8
Kirsch, I.R.9
-
24
-
-
0033556426
-
Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the beta-catenin gene
-
Koch A, Denkhaus D, Albrecht S, Leuschner I, Schweinitz D, Pietsch T. 1999. Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the beta-catenin gene. Cancer Res 59:269-273.
-
(1999)
Cancer Res
, vol.59
, pp. 269-273
-
-
Koch, A.1
Denkhaus, D.2
Albrecht, S.3
Leuschner, I.4
Schweinitz, D.5
Pietsch, T.6
-
25
-
-
0030975671
-
Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma
-
Korinek V, Barker N, Morin PJ, van Wichen D, de Weger R, Kinzler KW, Vogelstein B, Clevers H. 1997. Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma. Science 275:1784-1787.
-
(1997)
Science
, vol.275
, pp. 1784-1787
-
-
Korinek, V.1
Barker, N.2
Morin, P.J.3
Van Wichen, D.4
De Weger, R.5
Kinzler, K.W.6
Vogelstein, B.7
Clevers, H.8
-
26
-
-
2642698862
-
APC gene: Database of germline and somatic mutations in human tumors and cell lines
-
DOI 10.1093/nar/26.1.269
-
Laurent-Puig P, Beroud C, Soussi T. 1998. APC gene: Database of germline and somatic mutations in human tumors and cell lines. Nucleic Acids Res 26:269-270. (Pubitemid 28291541)
-
(1998)
Nucleic Acids Research
, vol.26
, Issue.1
, pp. 269-270
-
-
Laurent-Puig, P.1
Beroud, C.2
Soussi, T.3
-
27
-
-
0033780630
-
Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signaling
-
Liu W, Dong X, Mai M, Seelan RS, Taniguchi K, Krishnadath KK, Halling KC, Cunningham JM, Boardman LA, Qian C, Christensen E, Schmidt SS, Roche PC, Smith DI, Thibodeau SN. 2000. Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signaling. Nat Genet 26:146-147.
-
(2000)
Nat Genet
, vol.26
, pp. 146-147
-
-
Liu, W.1
Dong, X.2
Mai, M.3
Seelan, R.S.4
Taniguchi, K.5
Krishnadath, K.K.6
Halling, K.C.7
Cunningham, J.M.8
Boardman, L.A.9
Qian, C.10
Christensen, E.11
Schmidt, S.S.12
Roche, P.C.13
Smith, D.I.14
Thibodeau, S.N.15
-
28
-
-
1942541242
-
APC and CTNNB1 mutations in a large series of sporadic colorectal carcinomas stratified by the microsatellite instability status
-
DOI 10.1080/003655202760373407
-
Løvig T, Meling GI, Diep CB, Thorstensen L, Norheim Andersen S, Lothe RA, Rognum TO. 2002. APC and CTNNB1 mutations in a large series of sporadic colorectal carcinomas stratified by the microsatellite instability status. Scand J Gastroenterol 10:1184-1193. (Pubitemid 35178685)
-
(2002)
Scandinavian Journal of Gastroenterology
, vol.37
, Issue.10
, pp. 1184-1193
-
-
Lovig, T.1
Meling, G.I.2
Diep, C.B.3
Thorstensen, L.4
Norheim Andersen, S.5
Lothe, R.A.6
Rognum, T.O.7
-
29
-
-
0033565255
-
Beta-catenin mutations are specific for colorectal carcinomas with microsatellite instability but occur in endometrial carcinomas irrespective of mutator pathway
-
Mirabelli-Primdahl L, Gryfe R, Kim H, Millar A, Luceri C, Dale D, Holowaty E, Bapat B, Gallinger S, Redston M. 1999. Beta-catenin mutations are specific for colorectal carcinomas with microsatellite instability but occur in endometrial carcinomas irrespective of mutator pathway. Cancer Res 59:3346-3351.
-
(1999)
Cancer Res
, vol.59
, pp. 3346-3351
-
-
Mirabelli-Primdahl, L.1
Gryfe, R.2
Kim, H.3
Millar, A.4
Luceri, C.5
Dale, D.6
Holowaty, E.7
Bapat, B.8
Gallinger, S.9
Redston, M.10
-
30
-
-
0028291928
-
Characteristics of somatic mutation of the adenomatous polyposis coli gene in colorectal tumors
-
Miyaki M, Konishi M, Kikuchi-Yanoshita R, Enomoto M, Igari T, Tanaka K, Muraoka M, Takahashi H, Amada Y, Fukayama M, Maeda Y, Iwama T, Mishima Y, Mori T, Koike M. 1994. Characteristics of somatic mutation of the adenomatous polyposis coli gene in colorectal tumors. Cancer Res 54:3011-3020.
-
(1994)
Cancer Res
, vol.54
, pp. 3011-3020
-
-
Miyaki, M.1
Konishi, M.2
Kikuchi-Yanoshita, R.3
Enomoto, M.4
Igari, T.5
Tanaka, K.6
Muraoka, M.7
Takahashi, H.8
Amada, Y.9
Fukayama, M.10
Maeda, Y.11
Iwama, T.12
Mishima, Y.13
Mori, T.14
Koike, M.15
-
31
-
-
0033568145
-
Frequent mutation of beta-catenin and APC genes in primary colorectal tumors from patients with hereditary nonpolyposis colorectal cancer
-
Miyaki M, Iijima T, Kimura J, Yasuno M, Mori T, Hayashi Y, Koike M, Shitara N, Iwama T, Kuroki T. 1999. Frequent mutation of beta-catenin and APC genes in primary colorectal tumors from patients with hereditary nonpolyposis colorectal cancer. Cancer Res 59:4506-4509. (Pubitemid 29428947)
-
(1999)
Cancer Research
, vol.59
, Issue.18
, pp. 4506-4509
-
-
Miyaki, M.1
Iijima, T.2
Kimura, J.3
Yasuno, M.4
Mori, T.5
Hayashi, Y.6
Koike, M.7
Shitara, N.8
Iwama, T.9
Kuroki, T.10
-
32
-
-
0037302565
-
A novel case with germline p53 gene mutation having concurrent multiple primary colon tumours
-
DOI 10.1136/gut.52.2.304
-
Miyaki M, Iijima T, Ohue M, Kita Y, Hishima T, Kuroki T, Iwama T, Mori T. 2003. A novel case with germline p53 gene mutation having concurrent multiple primary colon tumors. Gut 52:304-306. (Pubitemid 36115077)
-
(2003)
Gut
, vol.52
, Issue.2
, pp. 304-306
-
-
Miyaki, M.1
Iijima, T.2
Ohue, M.3
Kita, Y.4
Hishima, T.5
Kuroki, T.6
Iwama, T.7
Mori, T.8
-
33
-
-
0026894053
-
Somatic mutations of the APC gene in colorectal tumors: Mutation cluster region in the APC gene
-
Miyoshi Y, Nagase H, Ando H, Horii A, Ichii S, Nakatsuru S, Aoki T, Miki Y, Mori T, Nakamura Y. 1992. Somatic mutations of the APC gene in colorectal tumors: Mutation cluster region in the APC gene. Hum Mol Genet 1:229-233.
-
(1992)
Hum Mol Genet
, vol.1
, pp. 229-233
-
-
Miyoshi, Y.1
Nagase, H.2
Ando, H.3
Horii, A.4
Ichii, S.5
Nakatsuru, S.6
Aoki, T.7
Miki, Y.8
Mori, T.9
Nakamura, Y.10
-
34
-
-
0030949463
-
Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
-
DOI 10.1126/science.275.5307.1787
-
Morin PJ, Sparks AB, Korinek V, Barker N, Clevers H, Vogelstein B, Kinzler KW. 1997. Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science 275:1787-1790. (Pubitemid 27136715)
-
(1997)
Science
, vol.275
, Issue.5307
, pp. 1787-1790
-
-
Morin, P.J.1
Sparks, A.B.2
Korinek, V.3
Barker, N.4
Clevers, H.5
Vogelstein, B.6
Kinzler, K.W.7
-
35
-
-
0344653592
-
A beta-catenin mutation in a sporadic colorectal tumor of the RER phenotype and absence of beta-catenin germline mutations in FAP patients
-
DOI 10.1002/(SICI)1098-2264(199805)22:1<37::AID-GCC5>3.0.CO;2-8
-
Muller O, Nimmrich I, Finke U, Friedl W, Hoffmann I. 1998. A beta-catenin mutation in a sporadic colorectal tumor of the RER phenotype and absence of beta-catenin germline mutations in FAP patients. Genes Chromosomes Cancer 22:37-41. (Pubitemid 28217804)
-
(1998)
Genes Chromosomes and Cancer
, vol.22
, Issue.1
, pp. 37-41
-
-
Muller, O.1
Nimmrich, I.2
Finke, U.3
Friedl, W.4
Hoffmann, I.5
-
36
-
-
0027417312
-
Germ-line mutations in the first 14 exons of the adenomatous polyposis coli (APC) gene
-
Olschwang S, Laurent-Puig P, Groden J, White R, Thomas G. 1993. Germ-line mutations in the first 14 exons of the adenomatous polyposis coli (APC) gene. Am J Hum Genet 52:273-279. (Pubitemid 23072409)
-
(1993)
American Journal of Human Genetics
, vol.52
, Issue.2
, pp. 273-279
-
-
Olschwang, S.1
Laurent-Puig, P.2
Groden, J.3
White, R.4
Thomas, G.5
-
37
-
-
12644274663
-
Alternative genetic pathways in colorectal carcinogenesis
-
DOI 10.1073/pnas.94.22.12122
-
Olschwang S, Hamelin R, Laurent-Puig P, Thuille B, De Rycke Y, Li YJ, Muzeau F, Girodet J, Salmon RJ, Thomas G. 1997. Alternative genetic pathways in colorectal carcinogenesis. Proc Natl Acad Sci USA 94:12122-12127. (Pubitemid 27467853)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.22
, pp. 12122-12127
-
-
Olschwang, S.1
Hamelin, R.2
Laurent-Puig, P.3
Thuille, B.4
De Rycke, Y.5
Li, Y.-J.6
Muzeau, F.7
Girodet, J.8
Salmon, R.-J.9
Thomas, G.10
-
38
-
-
0032168852
-
Infrequent somatic mutation of the adenomatous polyposis coli gene in aberrant crypt foci of human colon tissue
-
DOI 10.1002/(SICI)1097-0142(19980901)83:5<896::AID-CNCR14>3.0.CO;2- Q
-
Otori K, Konishi M, Sugiyama K, Hasebe T, Shimoda T, Kikuchi- Yanoshita R, Mukai K, Fukushima S, Miyaki M, Esumi H. 1998. Infrequent somatic mutation of the adenomatous polyposis coli gene in aberrant crypt foci of human colon tissue. Cancer 83:896-900. (Pubitemid 28401922)
-
(1998)
Cancer
, vol.83
, Issue.5
, pp. 896-900
-
-
Otori, K.1
Konishi, M.2
Sugiyama, K.3
Hasebe, T.4
Shimoda, T.5
Kikuchi-Yanoshita, R.6
Mukai, K.7
Fukushima, S.8
Miyaki, M.9
Esumi, H.10
-
39
-
-
0033895709
-
Wnt signaling and cancer
-
Polakis P. 2000. Wnt signaling and cancer. Genes Dev. 14:1837-1851.
-
(2000)
Genes Dev
, vol.14
, pp. 1837-1851
-
-
Polakis, P.1
-
40
-
-
0027763498
-
Molecular diagnosis of familial adenomatous polyposis
-
Powell SM, Petersen GM, Krush AJ, Booker S, Jen J, Giardiello FM, Hamilton SR, Vogelstein B, Kinzler KW. 1993. Molecular diagnosis of familial adenomatous polyposis. N Engl J Med 329:1982-1987.
-
(1993)
N Engl J Med
, vol.329
, pp. 1982-1987
-
-
Powell, S.M.1
Petersen, G.M.2
Krush, A.J.3
Booker, S.4
Jen, J.5
Giardiello, F.M.6
Hamilton, S.R.7
Vogelstein, B.8
Kinzler, K.W.9
-
41
-
-
0031551963
-
A National Cancer Institute Workshop on Hereditary Nonpolyposis Colorectal Cancer Syndrome: Meeting highlights and Bethesda guidelines
-
Rodriguez-Bigas MA, Boland CR, Hamilton SR, Henson DE, Jass JR, Khan PM, Lynch H, Perucho M, Smyrk T, Sobin L, Srivastava S. 1997. A National Cancer Institute Workshop on Hereditary Nonpolyposis Colorectal Cancer Syndrome: Meeting highlights and Bethesda guidelines. J Natl Cancer Inst 89:1758-1762.
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 1758-1762
-
-
Rodriguez-Bigas, M.A.1
Boland, C.R.2
Hamilton, S.R.3
Henson, D.E.4
Jass, J.R.5
Khan, P.M.6
Lynch, H.7
Perucho, M.8
Smyrk, T.9
Sobin, L.10
Srivastava, S.11
-
42
-
-
0034724186
-
APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits"
-
Rowan AJ, Lamlum H, Ilyas M, Wheeler J, Straub J, Papadopoulou A, Bicknell D, Bodmer WF, Tomlinson IP. 2000. APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits". Proc Natl Acad Sci USA 97:3352-3357.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3352-3357
-
-
Rowan, A.J.1
Lamlum, H.2
Ilyas, M.3
Wheeler, J.4
Straub, J.5
Papadopoulou, A.6
Bicknell, D.7
Bodmer, W.F.8
Tomlinson, I.P.9
-
43
-
-
0032836347
-
Colorectal cancer with and without microsatellite instability involves different genes
-
DOI 10.1002/(SICI)1098-2264(199911)26:3<247::AID-GCC9>3.0.CO;2-H
-
Salahshor S, Kressner U, Pâhlman L, Glimelius B, Lindmark G, Lindblom A. 1999. Colorectal cancer with and without microsatellite instability involves different genes. Genes Chromosomes Cancer 26:247-252. (Pubitemid 29468345)
-
(1999)
Genes Chromosomes and Cancer
, vol.26
, Issue.3
, pp. 247-252
-
-
Salahshor, S.1
Kressner, U.2
Pahlman, L.3
Glimelius, B.4
Lindmark, G.5
Lindblom, A.6
-
44
-
-
0034088858
-
AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1
-
Satoh S, Daigo Y, Furukawa Y, Kato T, Miwa N, Nishiwaki T, Kawasoe T, Ishiguro H, Fujita M, Tokino T, Sasaki Y, Imaoka S, Murata M, Shimano T, Yamaoka Y, Nakamura Y. 2000. AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1. Nat Genet 24:245-250.
-
(2000)
Nat Genet
, vol.24
, pp. 245-250
-
-
Satoh, S.1
Daigo, Y.2
Furukawa, Y.3
Kato, T.4
Miwa, N.5
Nishiwaki, T.6
Kawasoe, T.7
Ishiguro, H.8
Fujita, M.9
Tokino, T.10
Sasaki, Y.11
Imaoka, S.12
Murata, M.13
Shimano, T.14
Yamaoka, Y.15
Nakamura, Y.16
-
45
-
-
33646498125
-
Truncated APC is required for cell proliferation and DNA replication
-
Schneikert J and Behrens J. 2006. Truncated APC is required for cell proliferation and DNA replication. Int J Cancer 119: 74-79.
-
(2006)
Int J Cancer
, vol.119
, pp. 74-79
-
-
Schneikert, J.1
Behrens, J.2
-
46
-
-
33846626414
-
Truncated APC regulates the transcriptional activity of b-catenin in a cell cycle dependent manner
-
Schneikert J, Grohmann A, Behrens J. 2007. Truncated APC regulates the transcriptional activity of b-catenin in a cell cycle dependent manner. Hum Mol Genet 16:199-209.
-
(2007)
Hum Mol Genet
, vol.16
, pp. 199-209
-
-
Schneikert, J.1
Grohmann, A.2
Behrens, J.3
-
47
-
-
0036131933
-
Frequent alterations in the Wnt signaling pathway in colorectal cancer with microsatellite instability
-
Shimizu Y, Ikeda S, Fujimori M, Kodama S, Nakahara M, Okajima M, Asahara T. 2002. Frequent alterations in the Wnt signaling pathway in colorectal cancer with microsatellite instability. Genes Chromosomes Cancer 33:73-81.
-
(2002)
Genes Chromosomes Cancer
, vol.33
, pp. 73-81
-
-
Shimizu, Y.1
Ikeda, S.2
Fujimori, M.3
Kodama, S.4
Nakahara, M.5
Okajima, M.6
Asahara, T.7
-
48
-
-
0035210081
-
Frequent activation of the beta-catenin-Tcf signaling pathway in nonfamilial colorectal carcinomas with microsatellite instability
-
Shitoh K, Furukawa T, Kojima M, Konishi F, Miyaki M, Tsukamoto T, Nagai H. 2001. Frequent activation of the beta-catenin-Tcf signaling pathway in nonfamilial colorectal carcinomas with microsatellite instability. Genes Chromosomes Cancer 30:32-37.
-
(2001)
Genes Chromosomes Cancer
, vol.30
, pp. 32-37
-
-
Shitoh, K.1
Furukawa, T.2
Kojima, M.3
Konishi, F.4
Miyaki, M.5
Tsukamoto, T.6
Nagai, H.7
-
49
-
-
0037047057
-
Mutations in APC, Kirsten-ras, and p53-alternative genetic pathways to colorectal cancer
-
Smith G, Carey FA, Beattie J, Wilkie MJ, Lightfoot TJ, Coxhead J, Garner RC, Steele RJ, Wolf CR. 2002. Mutations in APC, Kirsten-ras, and p53-alternative genetic pathways to colorectal cancer. Proc Natl Acad Sci USA 99:9433-9438.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 9433-9438
-
-
Smith, G.1
Carey, F.A.2
Beattie, J.3
Wilkie, M.J.4
Lightfoot, T.J.5
Coxhead, J.6
Garner, R.C.7
Steele, R.J.8
Wolf, C.R.9
-
50
-
-
0032521433
-
Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer
-
Sparks AB, Morin PJ, Vogelstein B, Kinzler KW. 1998. Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer. Cancer Res 58:1130-1134.
-
(1998)
Cancer Res
, vol.58
, pp. 1130-1134
-
-
Sparks, A.B.1
Morin, P.J.2
Vogelstein, B.3
Kinzler, K.W.4
-
51
-
-
33744506902
-
Analysis of molecular alterations in left- and right-sided colorectal carcinomas reveals distinct pathways of carcinogenesis: Proposal for new molecular profile of colorectal carcinomas
-
Sugai T, Habano W, Jiao YF, Tsukahara M, Takeda Y, Otsuka K, Nakamura S. 2006. Analysis of molecular alterations in left- and right-sided colorectal carcinomas reveals distinct pathways of carcinogenesis: Proposal for new molecular profile of colorectal carcinomas. J Mol Diagn 8:193-201.
-
(2006)
J Mol Diagn
, vol.8
, pp. 193-201
-
-
Sugai, T.1
Habano, W.2
Jiao, Y.F.3
Tsukahara, M.4
Takeda, Y.5
Otsuka, K.6
Nakamura, S.7
-
52
-
-
33748506501
-
Mutations within Wnt pathway genes in sporadic colorectal cancers and cell lines
-
Suraweera N, Robinson J, Volikos E, Guenther T, Talbot I, Tomlinson I, Silver A. 2006. Mutations within Wnt pathway genes in sporadic colorectal cancers and cell lines. Int J Cancer 119:1837-1842.
-
(2006)
Int J Cancer
, vol.119
, pp. 1837-1842
-
-
Suraweera, N.1
Robinson, J.2
Volikos, E.3
Guenther, T.4
Talbot, I.5
Tomlinson, I.6
Silver, A.7
-
53
-
-
16944362068
-
Molecular analysis of the APC gene in 105 Dutch kindreds with familial adenomatous polyposis: 67 Germ-line mutations identified by DGGE, PTT, and southern analysis
-
vander Luijt RB, Khan PM, Vasen HF, Tops CM, van Leeuwen- Cornelisse IS, Wijnen JT, van der Klift HM, Plug RJ, Griffioen G, Fodde R. 1997. Molecular analysis of the APC gene in 105 Dutch kindreds with familial adenomatous polyposis: 67 germ-line mutations identified by DGGE, PTT, and southern analysis. Hum Mutat 9:7-16.
-
(1997)
Hum Mutat
, vol.9
, pp. 7-16
-
-
Vander Luijt, R.B.1
Khan, P.M.2
Vasen, H.F.3
Tops, C.M.4
Van Leeuwen- Cornelisse, I.S.5
Wijnen, J.T.6
Van Der Klift, H.M.7
Plug, R.J.8
Griffioen, G.9
Fodde, R.10
-
54
-
-
0030826757
-
Analyses of the APC and TGF-beta type II receptor genes, and microsatellite instability in mucosal colorectal carcinomas
-
Yagi OK, Akiyama Y, Ohkura Y, Ban S, Endo M, Saitoh K, Yuasa Y. 1997. Analyses of the APC and TGF-beta type II receptor genes, and microsatellite instability in mucosal colorectal carcinomas. Jpn J Cancer Res 88:718-724.
-
(1997)
Jpn J Cancer Res
, vol.88
, pp. 718-724
-
-
Yagi, O.K.1
Akiyama, Y.2
Ohkura, Y.3
Ban, S.4
Endo, M.5
Saitoh, K.6
Yuasa, Y.7
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