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Volumn 51, Issue 7, 2010, Pages 1991-2000

Paraoxonase 1 R/Q alleles are associated with differential accumulation of saturated versus 20:5n3 fatty acid in human adipose tissue

Author keywords

Dyslipidemia; Lipid homeostasis; Lipidomics

Indexed keywords

APOLIPOPROTEIN B; ARACHIDONIC ACID; ARYLDIALKYLPHOSPHATASE 1; ARYLESTERASE; DIHOMO GAMMA LINOLENIC ACID; DOCOSAHEXAENOIC ACID; HOMOCYSTEINE; ICOSAPENTAENOIC ACID; LINOLEIC ACID; LINOLENIC ACID; MONOUNSATURATED FATTY ACID; POLYUNSATURATED FATTY ACID; SATURATED FATTY ACID; TRANS FATTY ACID; ARYLDIALKYLPHOSPHATASE; FATTY ACID; LIPID; LIPOPROTEIN; UNSATURATED FATTY ACID;

EID: 77953481405     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.P004960     Document Type: Article
Times cited : (17)

References (47)
  • 1
    • 0025719481 scopus 로고
    • Characterization of cDNA clones encoding rabbit and human serum paraoxonase: The mature protein retains its signal sequence
    • Hassett, C., R. J. Richter, R. Humbert, C. Chapline, J. W. Crabb, C. J. Omiecinski, and C. E. Furlong. 1991. Characterization of cDNA clones encoding rabbit and human serum paraoxonase: the mature protein retains its signal sequence. Biochemistry. 30: 10141-10149.
    • (1991) Biochemistry , vol.30 , pp. 10141-10149
    • Hassett, C.1    Richter, R.J.2    Humbert, R.3    Chapline, C.4    Crabb, J.W.5    Omiecinski, C.J.6    Furlong, C.E.7
  • 2
    • 0025864611 scopus 로고
    • Paraoxonase prevents accumulation of lipoperoxides in low-density lipoprotein
    • Mackness, M. I., S. Arrol, and P. N. Durrington. 1991. Paraoxonase prevents accumulation of lipoperoxides in low-density lipoprotein. FEBS Lett. 286: 152-154.
    • (1991) FEBS Lett. , vol.286 , pp. 152-154
    • Mackness, M.I.1    Arrol, S.2    Durrington, P.N.3
  • 3
    • 0034804981 scopus 로고    scopus 로고
    • Oxidized LDL and HDL: Antagonists in atherothrombosis
    • Mertens, A., and P. Holvoet. 2001. Oxidized LDL and HDL: antagonists in atherothrombosis. FASEB J. 15: 2073-2084.
    • (2001) FASEB J. , vol.15 , pp. 2073-2084
    • Mertens, A.1    Holvoet, P.2
  • 4
    • 0032522985 scopus 로고    scopus 로고
    • Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions: A possible peroxidative role for paraoxonase
    • Aviram, M., M. Rosenblat, C. L. Bisgaier, R. S. Newton, S. L. Primo-Parmo, and B. N. La Du. 1998. Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase. J. Clin. Invest. 101: 1581-1590. (Pubitemid 28198486)
    • (1998) Journal of Clinical Investigation , vol.101 , Issue.8 , pp. 1581-1590
    • Aviram, M.1    Rosenblat, M.2    Bisgaier, C.L.3    Newton, R.S.4    Primo-Parmo, S.L.5    La Du, B.N.6
  • 6
    • 66949179058 scopus 로고    scopus 로고
    • Human paraoxonase gene cluster transgenic overexpression represses atherogenesis and promotes atherosclerotic plaque stability in ApoE-null mice
    • She, Z. G., W. Zheng, Y. S. Wei, H. Z. Chen, A. B. Wang, H. L. Li, G. Liu, R. Zhang, J. J. Liu, W. B. Stallcup, et al. 2009. Human paraoxonase gene cluster transgenic overexpression represses atherogenesis and promotes atherosclerotic plaque stability in ApoE-null mice. Circ. Res. 104: 1160-1168.
    • (2009) Circ. Res. , vol.104 , pp. 1160-1168
    • She, Z.G.1    Zheng, W.2    Wei, Y.S.3    Chen, H.Z.4    Wang, A.B.5    Li, H.L.6    Liu, G.7    Zhang, R.8    Liu, J.J.9    Stallcup, W.B.10
  • 7
    • 0027486997 scopus 로고
    • Molecular basis for the polymorphic forms of human serum paraoxonase/arylesterase: Glutamine or arginine at position 191, for the respective a or B allozymes
    • Adkins, S., K. N. Gan, M. Mody, and B. N. La Du. 1993. Molecular basis for the polymorphic forms of human serum paraoxonase/arylesterase: glutamine or arginine at position 191, for the respective A or B allozymes. Am. J. Hum. Genet. 52: 598-608. (Pubitemid 23311330)
    • (1993) American Journal of Human Genetics , vol.52 , Issue.3 , pp. 598-608
    • Adkins, S.1    Gan, K.N.2    Mody, M.3    La Du, B.N.4
  • 9
    • 0030293198 scopus 로고    scopus 로고
    • The effect of the human serum paraoxonase polymorphism is reversed with diazoxon, soman and sarin
    • Davies, H. G., R. J. Richter, M. Keifer, C. A. Broomfield, J. Sowalla, and C. E. Furlong. 1996. The effect of the human serum paraoxonase polymorphism is reversed with diazoxon, soman and sarin. Nat. Genet. 14: 334-336.
    • (1996) Nat. Genet. , vol.14 , pp. 334-336
    • Davies, H.G.1    Richter, R.J.2    Keifer, M.3    Broomfield, C.A.4    Sowalla, J.5    Furlong, C.E.6
  • 10
    • 0002198623 scopus 로고    scopus 로고
    • Paraoxonase polymorphism Met-Leu54 is associated with modified serum concentrations of the enzyme. A possible link between the paraoxonase gene and increased risk of cardiovascular disease in diabetes
    • Garin, M. C., R. W. James, P. Dussoix, H. Blanche, P. Passa, P. Froguel, and J. Ruiz. 1997. Paraoxonase polymorphism Met-Leu54 is associated with modified serum concentrations of the enzyme. A possible link between the paraoxonase gene and increased risk of cardiovascular disease in diabetes. J. Clin. Invest. 99: 62-66.
    • (1997) J. Clin. Invest. , vol.99 , pp. 62-66
    • Garin, M.C.1    James, R.W.2    Dussoix, P.3    Blanche, H.4    Passa, P.5    Froguel, P.6    Ruiz, J.7
  • 11
    • 67649690455 scopus 로고    scopus 로고
    • Paraoxonase 2 attenuates macrophage triglyceride accumulation via inhibition of diacylglycerol acyltransferase 1
    • Rosenblat, M., R. Coleman, S. T. Reddy, and M. Aviram. 2009. Paraoxonase 2 attenuates macrophage triglyceride accumulation via inhibition of diacylglycerol acyltransferase 1. J. Lipid Res. 50: 870-879.
    • (2009) J. Lipid Res. , vol.50 , pp. 870-879
    • Rosenblat, M.1    Coleman, R.2    Reddy, S.T.3    Aviram, M.4
  • 13
    • 0033537830 scopus 로고    scopus 로고
    • Oxidative stress disrupts insulin-induced cellular redistribution of insulin receptor substrate-1 and phosphatidylinositol 3-kinase in 3T3-L1 adipocytes. A putative cellular mechanism for impaired protein kinase B activation and GLUT4 translocation
    • Tirosh, A., R. Potashnik, N. Bashan, and A. Rudich. 1999. Oxidative stress disrupts insulin-induced cellular redistribution of insulin receptor substrate-1 and phosphatidylinositol 3-kinase in 3T3-L1 adipocytes. A putative cellular mechanism for impaired protein kinase B activation and GLUT4 translocation. J. Biol. Chem. 274: 10595-10602.
    • (1999) J. Biol. Chem. , vol.274 , pp. 10595-10602
    • Tirosh, A.1    Potashnik, R.2    Bashan, N.3    Rudich, A.4
  • 16
    • 61649111136 scopus 로고    scopus 로고
    • Prevalence of obesity and physical inactivity among farmers from Crete (Greece), four decades after the Seven Countries Study
    • Vardavas, C. I., M. Linardakis, C. Hatzis, W. Sarris, and A. Kafatos. 2008. Prevalence of obesity and physical inactivity among farmers from Crete (Greece), four decades after the Seven Countries Study. Nutr. Metab. Cardiovasc. Dis. 19: 153-155.
    • (2008) Nutr. Metab. Cardiovasc. Dis. , vol.19 , pp. 153-155
    • Vardavas, C.I.1    Linardakis, M.2    Hatzis, C.3    Sarris, W.4    Kafatos, A.5
  • 17
    • 61449148378 scopus 로고    scopus 로고
    • Relation ofPON1andCYP1A1genetic polymorphisms to clinical findings in a cross-sectional study of a Greek rural population professionally exposed to pesticides
    • 10.1016/j.toxlet.2008.10.018
    • Tsatsakis, A. M., A. Zafiropoulos, M. Tzatzarakis, G. N. Tzanakakis, and A. Kafatos. 2008. Relation ofPON1andCYP1A1genetic polymorphisms to clinical findings in a cross-sectional study of a Greek rural population professionally exposed to pesticides. Toxicol. Lett. 10.1016/j.toxlet.2008.10.018.
    • (2008) Toxicol. Lett.
    • Tsatsakis, A.M.1    Zafiropoulos, A.2    Tzatzarakis, M.3    Tzanakakis, G.N.4    Kafatos, A.5
  • 18
    • 3042722181 scopus 로고    scopus 로고
    • Significant involvement of CCR2-64I and CXCL12-3a in the development of sporadic breast cancer
    • Zafiropoulos, A., N. Crikas, A. M. Passam, and D. A. Spandidos. 2004. Significant involvement of CCR2-64I and CXCL12-3a in the development of sporadic breast cancer. J. Med. Genet. 41: e59.
    • (2004) J. Med. Genet. , vol.41
    • Zafiropoulos, A.1    Crikas, N.2    Passam, A.M.3    Spandidos, D.A.4
  • 19
    • 0022271253 scopus 로고
    • Rapid sampling and longterm storage of subcutaneous adipose-tissue biopsies for determination of fatty acid composition
    • Beynen, A. C., and M. B. Katan. 1985. Rapid sampling and longterm storage of subcutaneous adipose-tissue biopsies for determination of fatty acid composition. Am. J. Clin. Nutr. 42: 317-322.
    • (1985) Am. J. Clin. Nutr. , vol.42 , pp. 317-322
    • Beynen, A.C.1    Katan, M.B.2
  • 20
    • 2442464798 scopus 로고    scopus 로고
    • Depression and adipose polyunsaturated fatty acids in the survivors of the Seven Countries Study population of Crete
    • Mamalakis, G., M. Kiriakakis, G. Tsibinos, and A. Kafatos. 2004. Depression and adipose polyunsaturated fatty acids in the survivors of the Seven Countries Study population of Crete. Prostaglandins Leukot. Essent. Fatty Acids. 70: 495-501.
    • (2004) Prostaglandins Leukot. Essent. Fatty Acids , vol.70 , pp. 495-501
    • Mamalakis, G.1    Kiriakakis, M.2    Tsibinos, G.3    Kafatos, A.4
  • 22
    • 0038460302 scopus 로고    scopus 로고
    • The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: The JNC 7 report
    • Chobanian, A. V., G. L. Bakris, H. R. Black, W. C. Cushman, L. A. Green, J. L. Izzo, Jr., D. W. Jones, B. J. Materson, S. Oparil, J. T. Wright, Jr., et al. 2003. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA. 289: 2560-2572.
    • (2003) JAMA , vol.289 , pp. 2560-2572
    • Chobanian, A.V.1    Bakris, G.L.2    Black, H.R.3    Cushman, W.C.4    Green, L.A.5    Izzo Jr., J.L.6    Jones, D.W.7    Materson, B.J.8    Oparil, S.9    Wright Jr., J.T.10
  • 24
    • 0033461179 scopus 로고    scopus 로고
    • Determination of paraoxonase (PON1) status requires more than genotyping
    • Richter, R. J., and C. E. Furlong. 1999. Determination of paraoxonase (PON1) status requires more than genotyping. Pharmacogenetics. 9: 745-753.
    • (1999) Pharmacogenetics , vol.9 , pp. 745-753
    • Richter, R.J.1    Furlong, C.E.2
  • 25
    • 65549138006 scopus 로고    scopus 로고
    • Paraoxonases role in the prevention of cardiovascular diseases
    • Rosenblat, M., and M. Aviram. 2009. Paraoxonases role in the prevention of cardiovascular diseases. Biofactors. 35: 98-104.
    • (2009) Biofactors , vol.35 , pp. 98-104
    • Rosenblat, M.1    Aviram, M.2
  • 27
    • 0033973018 scopus 로고    scopus 로고
    • Promoter polymorphisms of human paraoxonase PON1 gene and serum paraoxonase activities and concentrations
    • Leviev, I., and R. W. James. 2000. Promoter polymorphisms of human paraoxonase PON1 gene and serum paraoxonase activities and concentrations. Arterioscler. Thromb. Vasc. Biol. 20: 516-521. (Pubitemid 30086111)
    • (2000) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.20 , Issue.2 , pp. 516-521
    • Leviev, I.1    James, R.W.2
  • 28
    • 0035826840 scopus 로고    scopus 로고
    • High-density lipoprotein loses its anti-inflammatory properties during acute influenza a infection
    • Van Lenten, B. J., A. C. Wagner, D. P. Nayak, S. Hama, M. Navab, and A. M. Fogelman. 2001. High-density lipoprotein loses its anti-inflammatory properties during acute influenza a infection. Circulation. 103: 2283-2288.
    • (2001) Circulation , vol.103 , pp. 2283-2288
    • Van Lenten, B.J.1    Wagner, A.C.2    Nayak, D.P.3    Hama, S.4    Navab, M.5    Fogelman, A.M.6
  • 29
    • 0346095221 scopus 로고    scopus 로고
    • Paraoxonase gene polymorphisms, oxidative stress, and diseases
    • Li, H. L., D. P. Liu, and C. C. Liang. 2003. Paraoxonase gene polymorphisms, oxidative stress, and diseases. J. Mol. Med. 81: 766-779.
    • (2003) J. Mol. Med. , vol.81 , pp. 766-779
    • Li, H.L.1    Liu, D.P.2    Liang, C.C.3
  • 33
    • 0032971881 scopus 로고    scopus 로고
    • Paraoxonase genes and disease
    • Hegele, R. A. 1999. Paraoxonase genes and disease. Ann. Med. 31: 217-224.
    • (1999) Ann. Med. , vol.31 , pp. 217-224
    • Hegele, R.A.1
  • 34
  • 35
    • 0031921406 scopus 로고    scopus 로고
    • Serum paraoxonase activity and its relationship to diabetic complications in patients with non-insulin-dependent diabetes mellitus
    • Ikeda, Y., T. Suehiro, M. Inoue, Y. Nakauchi, T. Morita, K. Arii, H. Ito, Y. Kumon, and K. Hashimoto. 1998. Serum paraoxonase activity and its relationship to diabetic complications in patients with non-insulin-dependent diabetes mellitus. Metabolism. 47: 598-602.
    • (1998) Metabolism , vol.47 , pp. 598-602
    • Ikeda, Y.1    Suehiro, T.2    Inoue, M.3    Nakauchi, Y.4    Morita, T.5    Arii, K.6    Ito, H.7    Kumon, Y.8    Hashimoto, K.9
  • 36
    • 0028883658 scopus 로고
    • Serum paraoxonase activity, concentration, and phenotype distribution in diabetes mellitus and its relationship to serum lipids and lipoproteins
    • Abbott, C. A., M. I. Mackness, S. Kumar, A. J. Boulton, and P. N. Durrington. 1995. Serum paraoxonase activity, concentration, and phenotype distribution in diabetes mellitus and its relationship to serum lipids and lipoproteins. Arterioscler. Thromb. Vasc. Biol. 15: 1812-1818.
    • (1995) Arterioscler. Thromb. Vasc. Biol. , vol.15 , pp. 1812-1818
    • Abbott, C.A.1    Mackness, M.I.2    Kumar, S.3    Boulton, A.J.4    Durrington, P.N.5
  • 37
    • 0035864342 scopus 로고    scopus 로고
    • PON2 gene variants are associated with clinical manifestations of cardiovascular disease in familial hypercholesterolemia patients
    • Leus, F. R., M. Zwart, J. J. Kastelein, and H. A. Voorbij. 2001. PON2 gene variants are associated with clinical manifestations of cardiovascular disease in familial hypercholesterolemia patients. Atherosclerosis. 154: 641-649.
    • (2001) Atherosclerosis , vol.154 , pp. 641-649
    • Leus, F.R.1    Zwart, M.2    Kastelein, J.J.3    Voorbij, H.A.4
  • 40
    • 0037411281 scopus 로고    scopus 로고
    • Selective mobilization of fatty acids from adipose tissue triacylglycerols
    • Raclot, T. 2003. Selective mobilization of fatty acids from adipose tissue triacylglycerols. Prog. Lipid Res. 42: 257-288.
    • (2003) Prog. Lipid Res. , vol.42 , pp. 257-288
    • Raclot, T.1
  • 41
    • 0013768710 scopus 로고
    • Fatty acid mobilization-mechanisms of regulation and metabolic consequences
    • Steinberg, D. 1963. Fatty acid mobilization-mechanisms of regulation and metabolic consequences. Biochem. Soc. Symp. 24: 111-143.
    • (1963) Biochem. Soc. Symp. , vol.24 , pp. 111-143
    • Steinberg, D.1
  • 42
    • 0000083865 scopus 로고
    • Effect of adrenaline, corticotropin, fasting, and diabetes on the composition of the longchain fatty acids of rat epididymal fat
    • Hollenberg, C. H., and D. E. Douglas. 1962. Effect of adrenaline, corticotropin, fasting, and diabetes on the composition of the longchain fatty acids of rat epididymal fat. Nature. 193: 1074-1075.
    • (1962) Nature , vol.193 , pp. 1074-1075
    • Hollenberg, C.H.1    Douglas, D.E.2
  • 43
    • 0024251403 scopus 로고
    • The lipid composition of adipose tissue
    • Body, D. R. 1988. The lipid composition of adipose tissue. Prog. Lipid Res. 27: 39-60.
    • (1988) Prog. Lipid Res. , vol.27 , pp. 39-60
    • Body, D.R.1
  • 44
    • 0028276264 scopus 로고
    • Individual fish-oil n-3 polyunsaturated fatty acid deposition and mobilization rates for adipose tissue of rats in a nutritional steady state
    • Raclot, T., and R. Groscolas. 1994. Individual fish-oil n-3 polyunsaturated fatty acid deposition and mobilization rates for adipose tissue of rats in a nutritional steady state. Am. J. Clin. Nutr. 60: 72-78. (Pubitemid 24215757)
    • (1994) American Journal of Clinical Nutrition , vol.60 , Issue.1 , pp. 72-78
    • Raclot, T.1    Groscolas, R.2
  • 45
    • 0030789804 scopus 로고    scopus 로고
    • Selective release of human adipocyte fatty acids according to molecular structure
    • Raclot, T., D. Langin, M. Lafontan, and R. Groscolas. 1997. Selective release of human adipocyte fatty acids according to molecular structure. Biochem. J. 324: 911-915. (Pubitemid 27285551)
    • (1997) Biochemical Journal , vol.324 , Issue.3 , pp. 911-915
    • Raclot, T.1    Langin, D.2    Lafontan, M.3    Groscolas, R.4
  • 46
    • 0028787925 scopus 로고
    • Selective mobilization of adipose tissue fatty acids during energy depletion in the rat
    • Raclot, T., and R. Groscolas. 1995. Selective mobilization of adipose tissue fatty acids during energy depletion in the rat. J. Lipid Res. 36: 2164-2173.
    • (1995) J. Lipid Res. , vol.36 , pp. 2164-2173
    • Raclot, T.1    Groscolas, R.2
  • 47
    • 0035816705 scopus 로고    scopus 로고
    • Apolipoprotein A-I promotes the formation of phosphatidylcholine core aldehydes that are hydrolyzed by paraoxonase (PON-1) during high density lipoprotein oxidation with a peroxynitrite donor
    • Ahmed, Z., A. Ravandi, G. F. Maguire, A. Emili, D. Draganov, B. N. La Du, A. Kuksis, and P. W. Connelly. 2001. Apolipoprotein A-I promotes the formation of phosphatidylcholine core aldehydes that are hydrolyzed by paraoxonase (PON-1) during high density lipoprotein oxidation with a peroxynitrite donor. J. Biol. Chem. 276: 24473-24481.
    • (2001) J. Biol. Chem. , vol.276 , pp. 24473-24481
    • Ahmed, Z.1    Ravandi, A.2    Maguire, G.F.3    Emili, A.4    Draganov, D.5    La Du, B.N.6    Kuksis, A.7    Connelly, P.W.8


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