Relationship of genetic polymorphisms in thymidylate synthase and alcohol drinking with risk of colorectal cancer

Chinese Journal of Cancer Prevention and Treatment

Volumn 16, Issue 8, 2009, Pages 568-572

  Zhang, Yan Ling ^a   Yuan, Xiao Yan ^a   Zhang, Zhong ^b   Yang, Huang ^a   Zhou, Yan Hong ^a   Pang, Yu Ming ^b   Zhou, Zi Yuan ^a   Liang, Hou Jie ^a   Cao, Jia ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b General Hospital of Steel Group Company   (China)

Author keywords

Alcohol drinking; Colorectal neoplasms; Genetic predisposition to disease; Polymorphism, genetic; Thymidylate synthase

Indexed keywords

ALCOHOL; THYMIDYLATE SYNTHASE;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ADULT; AGED; ARTICLE; CANCER RISK; CANCER SUSCEPTIBILITY; COLORECTAL CANCER; CONTROLLED STUDY; DRINKING BEHAVIOR; FEMALE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SMOKING;

EID: 77953470446     PISSN: 16735269     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Volcik K A, Shaw G M, Zhu H, et al. Associations between polymorphisms within the thymidylate synthase gene and spina bifida. Birth Defects Res[J]. A Clin Mol Teratol, 2003, 67(11):924-928.
2. Hori T, Ayusawa D, Glover T W, et al. Expression of fragile site on the human X chromosome in somatic cell hybrids between human fragile X cells and thymidylate synthase-negative mouse mutant cells[J]. Jpn J Cancer Res, 1985, 76(10):977-983. (Pubitemid 16198822)
3. Mandola M V, Stoehlmacher J, Muller-Weeks S, et al. A novel single nucleotide polymorphism of the thymidylate synthase gene abolishes USF-1 binding and alters transcriptional activity[J]. Cancer Res, 2003, 63(11):2898-2904.
4. Horie N, Aiba H, Oguro K, et al. Functional analysis and DNA polymorphism of the tandemly repeated sequences in the 5′-terminal regulatory region of the human gene for thymidylate synthase[J]. Cell Struct Funct, 1995, 20(3):191-197.
5. Kawakami K, Omura K, Kanehira E, et al. Polymorphic tandem repeats in the thymidylate synthase gene is associated with its protein expression in human gastrointestinal cancers[J]. Anticancer Res, 1999, 19(4B):3249-3252. (Pubitemid 30042617)
6. Chen J, Hunter D J, Stampfer M J, et al. Polymorphism in the thymidylate synthase promoter enhancer region modifies the risk and survival of colorectal cancer[J]. Cancer Epidemiol Biomarkers Prev, 2003, 12(10):958-962. (Pubitemid 37310249)
7. Adleff V, Hitre E, Koves I, et al. Heterozygote deficiency in thymidylate synthase enhancer region polymorphism genotype distribution in Hungarian colorectal cancer patients[J]. Int J Cancer, 2004, 108(6):852-856. (Pubitemid 38112613)
8. Ulrich C M, Bigler J, Bostick R, et al. Thymidylate synthase promoter polymorphism, interaction with folate intake, and risk of colorectal adenomas[J]. Cancer Res, 2002, 62(12):3361-3364. (Pubitemid 34651378)
9. Deng Y, Newman B, Dunne M P, et al. Case-only study of interactions between genetic polymorphisms of GSTM1, P1, T1 and Z1 and smoking in Parkinson's disease[J]. Neurosci Lett, 2004, 366(3):326-331.
10. Chen J, Kyte C, Chan W, et al. Polymorphism in the thymidylate synthase promoter enhancer region and risk of colorectal adenomas[J]. Cancer Epidemiol Biomarkers Prev, 2004, 13(12):2247-2250. (Pubitemid 40054324)