-
1
-
-
33645812129
-
Regulatory CD56 (bright) natural killer cells mediate immunomodulatory effects of IL-2 R alpha-targeted therapy (daclizumab) in multiple sclerosis
-
Bielekova, B., Catalfamo, M., Reichert-Scrivner, S., Packer, A., Cerna, M., Walmann, T. et al. (2006) Regulatory CD56 (bright) natural killer cells mediate immunomodulatory effects of IL-2 R alpha-targeted therapy (daclizumab) in multiple sclerosis. Proc Natl Acad Sci 103: 5941-5946.
-
(2006)
Proc Natl Acad Sci
, vol.103
, pp. 5941-5946
-
-
Bielekova, B.1
Catalfamo, M.2
Reichert-Scrivner, S.3
Packer, A.4
Cerna, M.5
Walmann, T.6
-
2
-
-
2942537826
-
Humanized anti-CD25 (daclizumab) inhibits disease activity in multiple sclerosis patients failing to respond to interferon beta
-
Bielekova, B., Richert, N., Howard, T., Blevins, G., Markovic-Plese, S., McCartin, J. et al. (2004) Humanized anti-CD25 (daclizumab) inhibits disease activity in multiple sclerosis patients failing to respond to interferon beta. Proc Natl Acad Sci 101: 8705-8708.
-
(2004)
Proc Natl Acad Sci
, vol.101
, pp. 8705-8708
-
-
Bielekova, B.1
Richert, N.2
Howard, T.3
Blevins, G.4
Markovic-Plese, S.5
McCartin, J.6
-
3
-
-
0036094448
-
Current immunotherapy for demyelinating diseases
-
Brashir, K. and Whitacker, J. ( 2002) Current immunotherapy for demyelinating diseases. Arch Neurol 59: 726-731.
-
(2002)
Arch Neurol
, vol.59
, pp. 726-731
-
-
Brashir, K.1
Whitacker, J.2
-
4
-
-
41649115484
-
Treating multiple sclerosis with monoclonal antibodies
-
Buttman, M. and Rieckmann, P. ( 2008) Treating multiple sclerosis with monoclonal antibodies. Expert Rev Neurother 8: 433-455.
-
(2008)
Expert Rev Neurother
, vol.8
, pp. 433-455
-
-
Buttman, M.1
Rieckmann, P.2
-
5
-
-
54149084585
-
Multiple sclerosis
-
Composton, A. and Coles, A. ( 2008) Multiple sclerosis. Lancet 372: 1502-1517.
-
(2008)
Lancet
, vol.372
, pp. 1502-1517
-
-
Composton, A.1
Coles, A.2
-
6
-
-
0024614839
-
Immunotherapy of experimental autoimmune encephalomyelitis (EAE): differential effect of anti-IL-2 receptor antibody therapy on actively induced and T-line mediated EAE of the Lewis Rat
-
Engelhardt, B., Diamanstein, T. and Wekerle, H. ( 1989) Immunotherapy of experimental autoimmune encephalomyelitis (EAE): differential effect of anti-IL-2 receptor antibody therapy on actively induced and T-line mediated EAE of the Lewis Rat. J Autoimmun 2: 61-73.
-
(1989)
J Autoimmun
, vol.2
, pp. 61-73
-
-
Engelhardt, B.1
Diamanstein, T.2
Wekerle, H.3
-
7
-
-
34548299105
-
Risk alleles for multiple sclerosis identified by a genomic study
-
Hafler, D., Comston, A., Sawcer, S., Lander, S., Daly, M., de Jager, P. et al. (2007) Risk alleles for multiple sclerosis identified by a genomic study. N Engl J Med 357: 851-862.
-
(2007)
N Engl J Med
, vol.357
, pp. 851-862
-
-
Hafler, D.1
Comston, A.2
Sawcer, S.3
Lander, S.4
Daly, M.5
de Jager, P.6
-
8
-
-
0023182056
-
Autoimmune effector cells: IX Inhibtion of adoptive transfer of autoimmune encephalomyelitis with a monoclonal antibody specific for interleukin 2 receptors
-
Hayosh, N. and Swanborg, R. ( 1987) Autoimmune effector cells: IX Inhibtion of adoptive transfer of autoimmune encephalomyelitis with a monoclonal antibody specific for interleukin 2 receptors. J Immunol 138: 3771-3775.
-
(1987)
J Immunol
, vol.138
, pp. 3771-3775
-
-
Hayosh, N.1
Swanborg, R.2
-
9
-
-
64549095397
-
A phase 2 randomized, double-blinded, placebo-controlled, multicenter study of subcutaneous daclizumab, a humanized anti-CD-25 monoclonal antibody, in patients with active, relapsing forms of multiple sclerosis - week 44 results
-
Kaufman, M.D., Wynn, D.R., Montalban, X., Wang, M. and Fong, A. ( 2008) A phase 2 randomized, double-blinded, placebo-controlled, multicenter study of subcutaneous daclizumab, a humanized anti-CD-25 monoclonal antibody, in patients with active, relapsing forms of multiple sclerosis - week 44 results. Neurology 70: PL01.003.
-
(2008)
Neurology
, vol.70
, pp. PL01.003
-
-
Kaufman, M.D.1
Wynn, D.R.2
Montalban, X.3
Wang, M.4
Fong, A.5
-
10
-
-
54349101744
-
Identification and development of new therapeutics for multiple sclerosis
-
Linker, R.A., Kieseier, B.C. and Gold, R. ( 2008) Identification and development of new therapeutics for multiple sclerosis. Trends Pharmacol Sci 29: 558-565.
-
(2008)
Trends Pharmacol Sci
, vol.29
, pp. 558-565
-
-
Linker, R.A.1
Kieseier, B.C.2
Gold, R.3
-
11
-
-
43249103954
-
Getting specific: monoclonal antibodies in multiple sclerosis
-
Lutterotti, A. and Martin, R. ( 2008) Getting specific: monoclonal antibodies in multiple sclerosis. Lancet Neurol 7: 538-547.
-
(2008)
Lancet Neurol
, vol.7
, pp. 538-547
-
-
Lutterotti, A.1
Martin, R.2
-
12
-
-
63449129990
-
(2009) Recurrent granuloma annulare during treatment with daclizumab
-
Mehta, L. and Rose, J.W. (2009) Recurrent granuloma annulare during treatment with daclizumab. Mult Scler 15: 527-528.
-
Mult Scler
, vol.15
, pp. 527-528
-
-
Mehta, L.1
Rose, J.W.2
-
13
-
-
0033764673
-
Advances in interleukin 2 receptor targeted treatment
-
(Suppl.
-
Morris, J.C. and Waldmann, T. ( 2000) Advances in interleukin 2 receptor targeted treatment. Ann Rheum Dis 59(Suppl. 1): i109-i114
-
(2000)
Ann Rheum Dis
, vol.59
, Issue.1
, pp. i109-i114
-
-
Morris, J.C.1
Waldmann, T.2
-
14
-
-
0034727066
-
Multiple sclerosis
-
Noseworthy, J. ( 2000) Multiple sclerosis. N Engl J Med 343: 938-952.
-
(2000)
N Engl J Med
, vol.343
, pp. 938-952
-
-
Noseworthy, J.1
-
15
-
-
13044311376
-
Treatment of noninfectious intermediate and posterior uveitis with humanized anti-TAC mAb: A phase I / II clinical trial
-
Nussenblatt, R.B., Fortin, E., Schiffman, R., Rizzo, L., Smith, J., van Veldhuisen, P. et al. (1999) Treatment of noninfectious intermediate and posterior uveitis with humanized anti-TAC mAb: A phase I / II clinical trial. Proc Natl Acad Sci 96: 7462-7466.
-
(1999)
Proc Natl Acad Sci
, vol.96
, pp. 7462-7466
-
-
Nussenblatt, R.B.1
Fortin, E.2
Schiffman, R.3
Rizzo, L.4
Smith, J.5
van Veldhuisen, P.6
-
16
-
-
18244401345
-
Initial evaluation of subcutaneous daclizumab treatment for noninfectious uveitis: a multicenter noncomparative interventional case series
-
Nussenblatt, R.B., Peterson, J.S., Foster, C.S., Rao, N.A., See, R.F., Letko, E. et al. (2005) Initial evaluation of subcutaneous daclizumab treatment for noninfectious uveitis: a multicenter noncomparative interventional case series. Ophthalmology 112: 764-770.
-
(2005)
Ophthalmology
, vol.112
, pp. 764-770
-
-
Nussenblatt, R.B.1
Peterson, J.S.2
Foster, C.S.3
Rao, N.A.4
See, R.F.5
Letko, E.6
-
17
-
-
0025797474
-
Chimeric cytotoxin IL2-PE40 inhibits EAE in the adoptive transfer model
-
Rose, J., Lorberboum-Galski, H., Fitzgerald, D., Hill, K., Townsend, J. and Pastan, I. ( 1991) Chimeric cytotoxin IL2-PE40 inhibits EAE in the adoptive transfer model. J Neuroimmunology 32: 209-217.
-
(1991)
J Neuroimmunology
, vol.32
, pp. 209-217
-
-
Rose, J.1
Lorberboum-Galski, H.2
Fitzgerald, D.3
Hill, K.4
Townsend, J.5
Pastan, I.6
-
18
-
-
34548142973
-
Daclizumab phase II trial in relapsing remitting multiple sclerosis: MRI and clinical results
-
Rose, J.W., Burns, J.B., Bjorklund, J., Klein, J., Watt, H.E. and Carlson, N.G. ( 2007) Daclizumab phase II trial in relapsing remitting multiple sclerosis: MRI and clinical results. Neurology 69: 785-789.
-
(2007)
Neurology
, vol.69
, pp. 785-789
-
-
Rose, J.W.1
Burns, J.B.2
Bjorklund, J.3
Klein, J.4
Watt, H.E.5
Carlson, N.G.6
-
20
-
-
9644265478
-
Treatment of multiple sclerosis with an anti-interleukin-2 receptor monoclonal antibody
-
Rose, J.W., Watt, H.E., White, A.T. and Carlson, N.G. ( 2004) Treatment of multiple sclerosis with an anti-interleukin-2 receptor monoclonal antibody. Ann Neurol 56: 864-867.
-
(2004)
Ann Neurol
, vol.56
, pp. 864-867
-
-
Rose, J.W.1
Watt, H.E.2
White, A.T.3
Carlson, N.G.4
-
21
-
-
56149086005
-
Spotlight on anti-CD25: daclizumab in MS
-
Schippling, D.S. and Martin, R. ( 2008) Spotlight on anti-CD25: daclizumab in MS. Int Mult Scler J 15: 94-98.
-
(2008)
Int Mult Scler J
, vol.15
, pp. 94-98
-
-
Schippling, D.S.1
Martin, R.2
-
22
-
-
34250024900
-
Direct inhibition of CD40L expression contributes to clinical efficacy of daclizumab independently of its effects on cell division and Th1/Th2 cytokine production
-
Snyder, J.T., Shen, J., Azmi, H., Hou, J., Fowler, D.H. and Ragheb, J.A. ( 2007) Direct inhibition of CD40L expression contributes to clinical efficacy of daclizumab independently of its effects on cell division and Th1/Th2 cytokine production. Blood 109: 5399-5406.
-
(2007)
Blood
, vol.109
, pp. 5399-5406
-
-
Snyder, J.T.1
Shen, J.2
Azmi, H.3
Hou, J.4
Fowler, D.H.5
Ragheb, J.A.6
-
23
-
-
17644396349
-
Immunology of multiple sclerosis
-
Sospedra, M. and Martin, R. ( 2005) Immunology of multiple sclerosis. Ann Rev Immunol 23: 683-747.
-
(2005)
Ann Rev Immunol
, vol.23
, pp. 683-747
-
-
Sospedra, M.1
Martin, R.2
-
24
-
-
6844236357
-
Interleukin-2-receptor blockade with daclizumab to prevent acute rejection in renal transplantation
-
Vincenti, F., Kirkman, R., Light, S., Bumgardner, G., Pescovitz, M., Halloran, P. et al. (1998) Interleukin-2-receptor blockade with daclizumab to prevent acute rejection in renal transplantation. N Engl J Med 338: 161-165.
-
(1998)
N Engl J Med
, vol.338
, pp. 161-165
-
-
Vincenti, F.1
Kirkman, R.2
Light, S.3
Bumgardner, G.4
Pescovitz, M.5
Halloran, P.6
-
25
-
-
0000167497
-
Emerging therapies: spectrum of applications of monoclonal antibody therapy
-
Waldmann, T., Levy, R. and Coller, B. ( 2000) Emerging therapies: spectrum of applications of monoclonal antibody therapy. Hematology 84: 394-406.
-
(2000)
Hematology
, vol.84
, pp. 394-406
-
-
Waldmann, T.1
Levy, R.2
Coller, B.3
|