Stability-indicating methods for the determination of famciclovir in the presence of its alkaline-induced degradation product

Drug Testing and Analysis

Volumn 2, Issue 4, 2010, Pages 188-199

  Lotfy, Hayam Mahmoud ^a   El Moneim Abosen, Mona M Abd ^b   EL Bardicy, Mohamed Galal ^b  

^a CAIRO UNIVERSITY   (Egypt)

^b Misr University for Science and Technology   (Egypt)

Author keywords

Densitometry; Derivative spectrophotometry; Famciclovir; Ferric hydroxamate; HPLC; Stability indicating method

Indexed keywords

ALKALINITY; CHLORINE COMPOUNDS; DEGRADATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ORGANIC ACIDS; REGRESSION ANALYSIS; SILICA GEL; SPECTROPHOTOMETRY; STABILITY;

ALKALINES; DEGRADATION PRODUCTS; DENSITOMETRY; DERIVATIVE SPECTROPHOTOMETRY; FAMCICLOVIR; FERRIC HYDROXAMATES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC; INDUCED DEGRADATION; PERFORMANCE; STABILITY INDICATING METHOD;

METHANOL;

ALKALI; CHLOROFORM; DIPOTASSIUM HYDROGEN PHOSPHATE; FAMCICLOVIR; FAMCLOVIR; FERRIC ION; HYDROXAMIC ACID; HYDROXYLAMINE; METHANOL; SILICA GEL; UNCLASSIFIED DRUG; 2 AMINOPURINE;

ACCURACY; ARTICLE; DRUG DEGRADATION; DRUG DETERMINATION; DRUG STABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; REGRESSION ANALYSIS; SEPARATION TECHNIQUE; ULTRAVIOLET SPECTROPHOTOMETRY; ANALOGS AND DERIVATIVES; COMPARATIVE STUDY; METABOLISM; PHARMACEUTICS; PROCEDURES; STANDARDS;

2-AMINOPURINE; ALKALIES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; SPECTROPHOTOMETRY, ULTRAVIOLET; TECHNOLOGY, PHARMACEUTICAL;

EID: 77953461279     PISSN: 19427603     EISSN: 19427611     Source Type: Journal    
DOI: 10.1002/dta.119     Document Type: Article

References (30)

1. A. C. Moffat, M. D. Osselton, B. Widdop, L. Y. Galichet, Clarke's Analysis of Drugs and Poisons, 3rd edn, Pharmaceutical Press: London, 2004.
2. S. K. Tyring, Clinical Therapeutics 1998, 20(4), 661.
3. R. Cirelli, K. Herne, M. Crary, P. Lee, S. K. Tyring, Antiviral Research 1996, 29(2-3), 141.
4. C. Arun, S. Tyring, K. Beutner, M. Rause, Antiviral Chemistry & Chemotherapy 2004, 15(5), 251.
5. R. Hodge, D. Sutton, M. Boyd, M. Harnden, R. Jarvest, Antimicrobial Agents & Chemotherapy 1989, 33(10), 1765.
6. G. Srinubabu, B. Sudharani, L. Sridhar, J. Rao, Chem. Pharm. Bull. 2006, 54(6), 819.
7. P. V. Reddy, B. S. Rani, E-J. Chem. 2006, 3(12), 154.
8. S. Nizamuddin, B. Gurupadayya, M. Ravi, Y. Manohara, S. Raju, Indian J. Pharm. Sci. 2007, 69, 451.
9. A. A. Gouda,Z. El-Shafey,N. Hossny,R. ElAzzazy, Acta AMol. Biomol. Spectrosc. 2008, 70(4), 785.
10. M. V. Krishna, P. V. Latha, D. G. Sankar, E-J. Chem. 2007, 4(1), 50.
11. C. Winton, S. Fowels, D. Pierce, A. Hodge, Analytical Proceedings 1990, 27(7), 181.
12. J. Chen, Yaowu Fenxi Zazhi. 2000, 20(3), 180.
13. Y. Zhang, L. Wang, Y. Guo, J. Cui, Zhongguo Yiyao Gongye Zazhi. 2002, 33(9), 454.
14. C. B. Raju, G. I. Panda, G. N. Rao, Chromatographia 2008, 68(9-10), 837.
15. S. Nizamuddin, B. Gurupadayya, M. Ravi, Y. Manohara, S. Raju, J. Pharm. Biomed. Anal. 2009, 50(5), 797.
16. H. Zongyu, J. Ou, Yaowu Fenxi Zazhi. 2000, 20(2), 111.
17. C. Li, Fenxi Ceshi Xuebao. 2006, 25(5), 102.
18. D. K. Bryant, M. D. Kingswood, A. Belengue, J. Chromatogr. A. 1996, 721(1), 41.
19. J. Mills,P. Volberding, L. Corey,AntiviralChemotherapy.1999, 5, 136.
20. ICH, Stability Testing of New Drug Substances and Products, International Conference on Harmonization, Geneva, 1993.
21. J. J. Nevado, J. R. Flores, M. J. Lierena, Anal. Lett. 1994, 27, 1009.
22. B. Niederursel, J. Wolfgang, J. Chromatogr. B. 1997, 692(2), 345.
23. J. A. Feldman, B. J. Robb, J. Pharmaceut. Sci. 2006, 59(11), 1646.
24. M. Abdel Kawy, S. M. Amer, H. M. Lotfy, H. E. Zaazaa, J.Bull. Fac. Pharm. Cairo Univ. 2008, 46(2), 1.
25. N. Grinberg, ModernThin-layer Chromatography,MarcelDekker Inc.: New York, 1990, p. 249.
26. W. Andrea, R. Phyllis, HPLC and CE principles and practice, Academic Press: London, 1997, p. 7.
27. J. A. Adamovics, Chromtographic analysis of pharmaceuticals, 2nd edn, Marcel Dekker Inc.: New York, 1997, pp. 11, 74.
28. The United States Pharmacopeia and National Formulary, the Official Compendia of Standards, Asian Edition, USP 30-NF 25 the United States Pharmacopeial Convention Inc., Rockville, MD, 2007.
29. ICH Q2A Note for guidance on validation of analytical methods: definition and terminology. International Conference on Harmonization, IFPMA, Geneva, 1994.
30. ICH Q2B, Note for guidance on validation of analytical methods methodology. International Conference on Harmonization, IFPMA, Geneva, 1996.