Membrane transporters: Structure, function and targets for drug design

Topics in Medicinal Chemistry

Volumn 4, Issue , 2009, Pages 15-51

  Ravna, Aina W ^a   Sager, Georg ^a   Dahl, Svein G ^a   Sylte, Ingebrigt ^a  

^a UNIVERSITY OF TROMSØ   (Norway)

Author keywords

Drug discovery; Drug targets; Membrane proteins; Three dimensional structure; Transporters

Indexed keywords

2 CHLORO N [ALPHA (2 PIPERIDINYL)BENZYL] 3 TRIFLUOROMETHYLBENZAMIDE; 4 AMINOBUTYRIC ACID CARRIER; ABC TRANSPORTER; AMINO ACID TRANSPORTER; CARBOHYDRATE; CARRIER PROTEIN; COTRANSPORTER; DICARBOXYLATE TRANSPORTER; DIPEPTIDE; DIPEPTIDE TRANSPOTER; DOPAMINE TRANSPORTER; EXCITATORY AMINO ACID TRANSPORTER 3; GLUTAMATE TRANSPORTER; GLYCINE TRANSPORTER; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 5; NEUROTRANSMITTER; NEUROTRANSMITTER TRANSPORTER; NORADRENALIN TRANSPORTER; NORADRENALIN UPTAKE INHIBITOR; POLYOL; REBOXETINE; SEROTONIN TRANSPORTER; SEROTONIN UPTAKE INHIBITOR; TIAGABINE; TRICYCLIC ANTIDEPRESSANT AGENT; UNCLASSIFIED DRUG; UNINDEXED DRUG; VESICULAR MONOAMINE TRANSPORTER 2;

AGITATION; AMINO ACID SEQUENCE; ANTIBIOTIC THERAPY; ANXIETY DISORDER; BINDING SITE; BIPOLAR DISORDER; CANCER CHEMOTHERAPY; CANCER RESISTANCE; CANCER THERAPY; CELL DIVISION; CHEMICAL STRUCTURE; CLINICAL TRIAL; CONSTIPATION; DEPRESSION; DIARRHEA; DIFFUSION; DIZZINESS; DRUG ABSORPTION; DRUG ABUSE; DRUG BINDING; DRUG DESIGN; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG RESEARCH; DRUG TARGETING; DRUG TRANSPORT; DRUG WITHDRAWAL; DYSPHORIA; ELECTRON MICROSCOPY; FATIGUE; FLU LIKE SYNDROME; HEADACHE; HUMAN; IMPOTENCE; INSOMNIA; LETHARGY; LIBIDO; LIGAND BINDING; METABOLITE; MIGRAINE; MOLECULAR RECOGNITION; MULTIDRUG RESISTANCE; NAUSEA; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OBSESSIVE COMPULSIVE DISORDER; PANIC; PARESTHESIA; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; RESTLESSNESS; REVIEW; SCHIZOPHRENIA; SIDE EFFECT; SOCIAL PHOBIA; SWEATING; TACHYCARDIA; THREE DIMENSIONAL IMAGING; URINE RETENTION; VERTIGO; VOMITING; X RAY CRYSTALLOGRAPHY; XEROSTOMIA;

EID: 77953424444     PISSN: 18622461     EISSN: 1862247X     Source Type: Book Series    
DOI: 10.1007/7355_2008_023     Document Type: Review

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