-
1
-
-
66749138107
-
Interview with Pedro Cuatrecasas
-
Cuatrecasas P. Interview with Pedro Cuatrecasas. Nat. Rev. Drug Discov. 8, 446 (2009).
-
(2009)
Nat. Rev. Drug Discov.
, vol.8
, pp. 446
-
-
Cuatrecasas, P.1
-
2
-
-
77953461094
-
Development and application of a high throughput formulation screening strategy in drug discovery
-
In Press
-
Gopinathan S, Nouraldeen A, Wilson AGE. Development and application of a high throughput formulation screening strategy in drug discovery. Curr. Drug Discovery Tech. (2009) (In Press).
-
(2009)
Curr. Drug Discovery Tech.
-
-
Gopinathan, S.1
Nouraldeen, A.2
Wilson, A.G.E.3
-
5
-
-
25844521587
-
Drug delivery: Oral route
-
(3rd Edition). Informa Healthcare London UK
-
Singh BN, Kim KH. Drug delivery: oral route. In: Encyclopedia of Pharmaceutical Technology (3rd Edition). Informa Healthcare, London, UK 1242-1265 (2006).
-
(2006)
Encyclopedia of Pharmaceutical Technology
, pp. 1242-1265
-
-
Singh, B.N.1
Kim, K.H.2
-
6
-
-
33947174194
-
An integrated early formulation strategy - From hit evaluation to preclinical candidate profiling
-
Maas J, Kamm W, Hauck G. An integrated early formulation strategy - from hit evaluation to preclinical candidate profiling. Eur. J. Pharm. Biopharm. 66, 1-10 (2007).
-
(2007)
Eur. J. Pharm. Biopharm.
, vol.66
, pp. 1-10
-
-
Maas, J.1
Kamm, W.2
Hauck, G.3
-
7
-
-
33846290338
-
Preclinical formulations for discovery and toxicology: Physicochemical challenges
-
Neervannan N. Preclinical formulations for discovery and toxicology: physicochemical challenges. Expert Opin. Drug Metabol. Toxicol. 2, 715-731 (2006).
-
(2006)
Expert Opin. Drug Metabol. Toxicol.
, vol.2
, pp. 715-731
-
-
Neervannan, N.1
-
8
-
-
34447646495
-
Developing early formulations: Practice and perspective
-
Li P, Zhao L. Developing early formulations: practice and perspective. Int. J. Pharm. 341, 1-19 (2007).
-
(2007)
Int. J. Pharm.
, vol.341
, pp. 1-19
-
-
Li, P.1
Zhao, L.2
-
9
-
-
0034002261
-
Role of the development scientist in compound lead selection and optimization
-
Venkatesh S, Lipper RA. Role of the development scientist in compound lead selection and optimization. J. Pharm. Sci. 89, 145-154 (2000).
-
(2000)
J. Pharm. Sci.
, vol.89
, pp. 145-154
-
-
Venkatesh, S.1
Lipper, R.A.2
-
10
-
-
0037422391
-
An intravenous formulation decision tree for discovery compound formulation development
-
Lee YC, Zocharski PD, Samas B. An intravenous formulation decision tree for discovery compound formulation development. Int. J. Pharm. 253, 111-119 (2003).
-
(2003)
Int. J. Pharm.
, vol.253
, pp. 111-119
-
-
Lee, Y.C.1
Zocharski, P.D.2
Samas, B.3
-
11
-
-
0036805875
-
Improved oral bioavailability of cyclosporin A in male Wistar rats: Comparison of a Solutol HS 15 containing self-dispersing formulation and a microsuspension
-
Gonzalez RCB, Huwyler J, Walter I, Mountfield R, Bittner B. Improved oral bioavailability of cyclosporin A in male Wistar rats: comparison of a Solutol HS 15 containing self-dispersing formulation and a microsuspension. Int. J. Pharm. 245, 143-151 (2002).
-
(2002)
Int. J. Pharm.
, vol.245
, pp. 143-151
-
-
Gonzalez, R.C.B.1
Huwyler, J.2
Walter, I.3
Mountfield, R.4
Bittner, B.5
-
12
-
-
58149216403
-
Improving glyburide solubility and dissolution by complexation with hydroxybutenyl-b-cyclodextrin
-
Klein S, Wempe MF, Zoeller T et al. Improving glyburide solubility and dissolution by complexation with hydroxybutenyl-b-cyclodextrin. J. Pharm. Pharmacol. 61, 23-30 (2009).
-
(2009)
J. Pharm. Pharmacol.
, vol.61
, pp. 23-30
-
-
Klein, S.1
Wempe, M.F.2
Zoeller, T.3
-
13
-
-
0035289779
-
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
-
Lipinski CA, Lombardo F, Dominy BW, Feeney PJ. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv. Drug Delivery Rev. 46, 3-26 (2001).
-
(2001)
Adv. Drug Delivery Rev.
, vol.46
, pp. 3-26
-
-
Lipinski, C.A.1
Lombardo, F.2
Dominy, B.W.3
Feeney, P.J.4
-
14
-
-
21844459973
-
2-hydroxypropyl-b-cyclodextrin (HP-b-CD): A toxicology review
-
Gould S, Scott RC. 2-hydroxypropyl-b-cyclodextrin (HP-b-CD): a toxicology review. Food Chem. Toxicol. 43, 1451-1459 (2005).
-
(2005)
Food Chem. Toxicol.
, vol.43
, pp. 1451-1459
-
-
Gould, S.1
Scott, R.C.2
-
15
-
-
33845457251
-
Nonclinical vehicle use in studies by multiple routes in multiple species
-
Gad SC, Cassidy CD, Aubert N, Spainhour B, Robbe H. Nonclinical vehicle use in studies by multiple routes in multiple species. Int. J. Toxicol. 25, 499-521 (2006).
-
(2006)
Int. J. Toxicol.
, vol.25
, pp. 499-521
-
-
Gad, S.C.1
Cassidy, C.D.2
Aubert, N.3
Spainhour, B.4
Robbe, H.5
-
16
-
-
33747889758
-
Effect of commonly used vehicles on gastrointestinal, renal, and liver function in rats
-
Pestel S, Martin H-J, Maier G-M, Guth B. Effect of commonly used vehicles on gastrointestinal, renal, and liver function in rats. J. Pharmacol. Toxicol. Methods 54, 200-214 (2006).
-
(2006)
J. Pharmacol. Toxicol. Methods
, vol.54
, pp. 200-214
-
-
Pestel, S.1
Martin, H.-J.2
Maier, G.-M.3
Guth, B.4
-
17
-
-
1242337285
-
Solubilizing excipients in oral and injectable formulations
-
Strickley G. Solubilizing excipients in oral and injectable formulations. Pharm. Res. 21, 201-230 (2004).
-
(2004)
Pharm. Res.
, vol.21
, pp. 201-230
-
-
Strickley, G.1
-
18
-
-
4344645978
-
Can the pharmaceutical industry reduce attrition rates?
-
Kola I, Landis J. Can the pharmaceutical industry reduce attrition rates? Nat. Rev. Drug Discov. 3(8), 711-715 (2004).
-
(2004)
Nat. Rev. Drug Discov.
, vol.3
, Issue.8
, pp. 711-715
-
-
Kola, I.1
Landis, J.2
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