A hypokalemic muscular weakness after licorice ingestion: A case report

Cases Journal

Volumn 2, Issue 9, 2009, Pages

  Meltem, Akkas Camkurt ^a   Figen, Coskun ^a   Nalan, Metin Aksu ^a   Mahir, Kunt ^a   Sebnem, Bozkurt ^a   Mehlika, Isildak ^a   Kasim, Kilic Ahmet ^a   Miyase, Bayraktar ^a  

^a HACETTEPE UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

POTASSIUM; POTASSIUM CHLORIDE;

ADULT; ARTICLE; CASE REPORT; DIFFERENTIAL DIAGNOSIS; DISEASE COURSE; GLYCYRRHIZA; HEART VENTRICLE FIBRILLATION; HUMAN; HYPOCALCEMIA; HYPOKALEMIA; LABORATORY TEST; MAGNETIC RESONANCE ANGIOGRAPHY; MALE; MULTIPLE SCLEROSIS; MUSCLE WEAKNESS; NEUROLOGIC EXAMINATION; NUCLEAR MAGNETIC RESONANCE IMAGING; PARALYSIS; PHYSICAL EXAMINATION; POTASSIUM BLOOD LEVEL; RHABDOMYOLYSIS; SMOKING CESSATION; TREATMENT RESPONSE;

EID: 77953410638     PISSN: 17571626     EISSN: None     Source Type: Journal    
DOI: 10.4076/1757-1626-2-8053     Document Type: Article

References (11)

1. Van den Bosch AE, van der Klooster JM, Zuidgeest DM, Ouwendijk RJ, Dees A: Severe hypokalaemic paralysis and rhabdomyolysis due to ingestion of licorice. Neth J Med 2005, 63:146-148.
2. Kusano E: How to diagnose and treat a licorice-induced syndrome with findings similar to that of primary hyperaldosteronism. Intern Med 2004, 43:5-6.
3. Ohtake N, Kido A, Kubota K, Tsuchiya N, Morita T, Kase Y, Takeda S: A possible involvement of 3-monoglucuronyl-glycyrrhetinic acid, a metabolite of glycyrrhizin(GL), in GL-induced pseudoaldosteronism. Life Sciences 2007, 80:1545-1552.
4. Mumoli N, Cei M: Licorice-induced hypokalemia. Int J Cardiol 2008, 82:208.
5. Hamidon BB, Jeyabalan V: Exogenously-induced apparent hyper-mineralocorticoidism associated with ingestion of 'asam boi. Singapore Med J 2006, 47:156-158.
6. Lin SH, Yang SS, Chau T, Halperin ML: An unusual cause of hypokalemic paralysis: chronic licorice ingestion. Am J Med Sci 2003, 325:153-156.
7. Elinav E, Chajek-Shaul T: Licorice consumption causing severe hypokalemic paralysis. Mayo Clin Proc 2003, 78:767-768.
8. Kageyama Y, Suzuki H, Saruta T: Glycyrrhizin induced mineralocorticoid activity through alterations in cortisol metabolism in the human kidney. J Endocrinol 1997, 135:147-152.
9. Con JW, Rovner DR, Cohen EL: Licorice induced pseudoaldosteronism. Hypertension, hypokalemia, aldosteronopenia, and suppressed plasma renin activity. JAMA 1968, 205:492-496.
10. Yasue H, Itoh T, Mizuno Y, Harada E: Severe hypokalemia, rhabdomyolysis, muscle paralysis and respiratory impairment in a hypertensive patient taking herbal medicines containing licorice. Intern Med 2007, 46:575-578.
11. Draper N, Stewart PM: 11 Beta-hydroxysteroid dehydrogenase and the pre-receptor regulation of corticosteroid hormone action. J Endocrinol 2005, 186:251-271.